KEGG   Felis catus (domestic cat): 101087073
Entry
101087073         CDS       T02385                                 
Symbol
PTPN6
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 6 isoform X2
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
fca  Felis catus (domestic cat)
Pathway
fca04520  Adherens junction
fca04630  JAK-STAT signaling pathway
fca04650  Natural killer cell mediated cytotoxicity
fca04660  T cell receptor signaling pathway
fca04662  B cell receptor signaling pathway
fca05140  Leishmaniasis
fca05205  Proteoglycans in cancer
fca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    101087073 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    101087073 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    101087073 (PTPN6)
   04660 T cell receptor signaling pathway
    101087073 (PTPN6)
   04662 B cell receptor signaling pathway
    101087073 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101087073 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101087073 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    101087073 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:fca01009]
    101087073 (PTPN6)
Enzymes [BR:fca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     101087073 (PTPN6)
Protein phosphatases and associated proteins [BR:fca01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    101087073 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase HGAL
Other DBs
NCBI-GeneID: 101087073
NCBI-ProteinID: XP_003988392
Ensembl: ENSFCAG00000004287
LinkDB
Position
B4:41990888..42005680
AA seq 595 aa
MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDF
YDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQA
ETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGG
SETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEETA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHTRVILQGRDSNIPGSD
YINANYVKNQLLSPDENAKTYIASQGCLETTVNDFWQMAWQENTRVIVMTTREVEKGRNK
CVPYWPEVGTQRAYGPYTVTNCGEHDTAEYKLRTLQVSPLDNGDLVREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDC
DIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVIQSQKGRESEYGNIT
YPLAMKNAHAKASRTSSKHKEDVYENLHSKNKKEDKVKKQRSADKEKSKGSLKRK
NT seq 1788 nt   +upstreamnt  +downstreamnt
atggtgaggtggtttcaccgagacctcagtgggctggatgcagagacgctgctcaagggc
cgcggggtccatgggagcttcttggctcggcccagtcgcaagaaccagggcgacttctcc
ctctccgtcagggtcggggatcaggtgacccacattcggatccagaactcgggagatttc
tatgacctgtacggaggggagaagtttgcgacactgacggagctggtggagtactacaca
cagcagcagggtgtcctgcaggaccgggatggcaccatcatccacctcaagtacccactg
aactgctccgaccccaccagcgagaggtggtaccacggtcacatgtctggggggcaggca
gagacactgctgcaggccaagggtgagccctggacgtttctcgtgcgtgagagtctcagc
cagcctggagattttgtgctgtccgtgctcagcgaccagcccaaggctggcccaggctcc
ccactcagagtcactcatatcaaggtcatgtgtgagggtggacgctacacggtgggtggc
tcagagacctttgacagcctcacagacctggtggagcatttcaagaagacggggattgag
gaggcctcgggtgccttcgtctacctgcggcagccgtactatgccactcgggtgaacgca
gctgacattgagaatcgggtgttggaactcaacaagaagcaggagtcggaggagacagcc
aaagccggcttttgggaggagttcgagagtctgcagaagcaggaggtaaagaacttgcac
cagcggctggaaggccagaggccagagaacaagagcaagaaccgttacaagaacattctt
ccgttcgaccacacccgagtgatcctgcagggacgtgacagcaacatccctgggtccgac
tatatcaatgccaactacgtcaagaaccagctgctaagccccgatgagaacgctaagacc
tacatcgccagccagggctgcctggagaccacagtcaacgacttctggcagatggcatgg
caggagaacacccgcgtcattgtcatgaccacccgagaggtggagaaaggccggaacaaa
tgtgtgccatattggccagaggtgggcactcagcgcgcttatggaccgtacacagtaacc
aattgcggggagcacgacacagctgagtacaaactccgtaccttgcaggtctccccgctg
gacaatggggacctggttcgggagatctggcactatcagtacctgagctggcctgaccat
ggcgtccccagcgagcctgggggtgtcctcagcttcctggatcagatcaaccagcggcag
gagagtctgcctcacgcgggacccatcattgtgcactgcagcgcaggcattggccgcacg
ggcaccatcatcgtcatcgacatgctcatggaaagcatctccaccaaggggttggactgt
gacatcgacatccagaagaccatccagatggtgcgggcgcagcgctccggcatggtgcag
accgaggcgcagtacaagttcatctatgtggccatcgcccagttcattgaaaccaccaag
aagaagctggaggtcattcagtcccagaagggccgggagtcagagtacgggaacatcacc
taccccttagccatgaagaacgcccatgccaaggcatcccgcacctcttccaaacacaag
gaggatgtatatgagaacttgcacagtaagaacaagaaggaagacaaggtgaagaagcag
cggtcggcggacaaggagaagagcaagggttccctcaagaggaaatga

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