Felis catus (domestic cat): 101091840
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Entry
101091840 CDS
T02385
Symbol
HSD17B4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2 isoform X2
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00120
Primary bile acid biosynthesis
fca01040
Biosynthesis of unsaturated fatty acids
fca01100
Metabolic pathways
fca01212
Fatty acid metabolism
fca04146
Peroxisome
Module
fca_M00861
beta-Oxidation, peroxisome, VLCFA
fca_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
101091840 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
101091840 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
101091840 (HSD17B4)
Enzymes [BR:
fca01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
101091840 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
101091840 (HSD17B4)
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GFIT
Motif
Pfam:
adh_short
MFE-2_hydrat-2_N
MaoC_dehydratas
adh_short_C2
SCP2
KR
Alkyl_sulf_C
FAS1_DH_region
Epimerase
HerA_C
Motif
Other DBs
NCBI-GeneID:
101091840
NCBI-ProteinID:
XP_006927609
UniProt:
M3W9K8
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Position
A1:97752796..97840141
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AA seq
736 aa
AA seq
DB search
MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFRGVGKGSSAADKVVE
EIRSKGGKAVANYDSVEAGEKVVKTALDAFGRIDVVVNNAGILRDGSFARISDEDWDIIH
RVHLRGSFRVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYSAAKLGLLGLSNTIAL
EGKKSNIHCNTIAPTAGSRMTQTVMPEDLLETLKPDYVAPLVLWLCHESCEENGGLFEVG
GGWIGKLRWERSLGAIVRQKNQPMTPEGVKANWKKICDFENATKPQRIQESVGSIIGVVS
KIDSDGGVSTNHTSHAASTAPSGFAGAIGYKFPPFSSAYTELETIMYALGVGASVKEPKD
MKFIYEGSSDFSCLPTFGVIVAQKPLVDGGLGEVPELPVSLEKVLHGEQYLELYKPLPRS
GNLKCEAVIADVLDKGSGLVILMDVYSYFEKELICYNQFSLFLVGSGGIGGKRTSDKVKE
AVAVPNRPPDAVLTDVTSLNQAALYRLSGDWNPLHIDPNFSSFAGFDKPILHGLCTFGFS
ARHVLQKFADNDASRFKAIKVRFSKPVYPGQTIKTEMWKEGNRIHFQTKIHETGDIIISN
AYVDLVPASGISAKTSSAREELQSTLVFEEIGRRLRDIGHEVVKKVDAVFEWHITKDGNT
AAKWTIDLKNGSGKVYQGPAVGSADTTFTLSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
LLSQKLQMILKDYAKL
NT seq
2211 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgccgctgcgattcgacgggcgggtggtactggtcaccggcgcggggggagga
ctgggccgagcctatgccctggcgtttgcagaaagaggtgcatcagttgttgtgaatgac
ctaggtggggacttcaggggagttggtaaaggctcctctgctgctgataaggttgttgaa
gaaataagaagtaaaggtggaaaagccgtggccaactatgattcagtagaagcaggagag
aaggttgtgaagacagcactggacgcttttggaagaatagatgttgtggtcaacaatgct
ggaattctgagggatggttcttttgctagaataagtgatgaagactgggatataatccat
agagtccatttacgaggctcattccgagtgacccgggcggcttgggatcatatgaagaaa
cagaagtttgggaggattattatgacttcatcagcttcaggaatatacggcaactttggc
caggccaattatagtgctgcgaagctgggtcttctgggcctttcaaacactattgcactt
gaaggcaagaaaagcaacattcactgtaacactattgcccctacagctggatcccggatg
acccagacagttatgcctgaagatctcctggaaactttgaagcctgattacgtggcgccc
ttggtcctttggctttgccatgagagctgtgaggaaaacggtggcttgtttgaggttgga
ggaggatggattggaaaattacgctgggagcggtcccttggagccatcgtaagacagaag
aatcaacccatgacccctgagggggtgaaggctaattggaagaagatctgtgactttgag
aacgccaccaagccccagagaattcaagaatcagttggcagtataattggagttgtaagt
aaaatcgattcagatggaggagtttcgacaaatcatacgagtcacgcagcatcgacagca
ccatcaggatttgctggagccattggctataaattccctccattttcttctgcttacacg
gagctggaaactattatgtatgcccttggcgtgggagcatcggtgaaggagccaaaagat
atgaaatttatatacgaaggaagctctgacttctcctgtttgcctacatttggagttatc
gtagctcagaaacctttagtagatggagggttgggagaggttcctgagcttccggtcagc
ttggaaaaggttctccatggggagcagtacttggagttgtataaaccacttcccagatca
ggaaacttaaaatgtgaagctgttattgccgacgtcctagataaaggatctggtttagta
attcttatggatgtctattcttattttgagaaggaacttatatgttacaatcagttctct
ctcttcctcgttggctctggaggcattggtggaaaacggacgtcagacaaagtcaaggaa
gctgtagctgtgcctaatagacctcctgatgctgtacttacagatgtcacctcacttaat
caggctgctttgtaccgcctcagtggcgactggaatcccttacacattgatcctaacttc
tctagtttcgctggttttgacaagcccatattacatggattatgtacatttggattttct
gccaggcatgtattacagaagtttgcagataatgatgcatcaagattcaaggcaattaag
gttcgtttttcaaaaccagtatatccaggacagactataaaaactgagatgtggaaagaa
ggaaatagaattcatttccaaaccaagattcatgaaaccggagacatcatcatttcaaat
gcgtatgtggatcttgtgccagcatctggtatttcagctaagacatcctctgcgcgtgag
gagcttcagagtaccctggtgtttgaggaaataggtcgccgccttagggatatcgggcat
gaggtggtgaagaaagtggatgctgtgtttgagtggcacatcactaaagatggaaacact
gcagccaagtggactattgacctaaaaaatggttctggaaaagtctatcaaggccctgca
gtaggctctgcggatacgaccttcacactttcagacgaagatttcatggaggtagtcctg
ggcaagcttgaccctcagaaggcattctttagtggcagactgaaggccagagggaacatc
ttgctgagccagaagcttcagatgattcttaaagactatgccaagctgtga
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