Felis catus (domestic cat): 101092339 Help Entry 101092339         CDS       T02385                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism fca  Felis catus (domestic cat) Pathway fca04062   Chemokine signaling pathway fca04151   PI3K-Akt signaling pathway fca04217   Necroptosis fca04550   Signaling pathways regulating pluripotency of stem cells fca04630   JAK-STAT signaling pathway fca04658   Th1 and Th2 cell differentiation fca04659   Th17 cell differentiation fca05161   Hepatitis B fca05162   Measles fca05166   Human T-cell leukemia virus 1 infection fca05169   Epstein-Barr virus infection fca05200   Pathways in cancer fca05203   Viral carcinogenesis fca05223   Non-small cell lung cancer fca05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:fca00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101092339 (JAK3)    04151 PI3K-Akt signaling pathway     101092339 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101092339 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     101092339 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     101092339 (JAK3)    04659 Th17 cell differentiation     101092339 (JAK3)    04062 Chemokine signaling pathway     101092339 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101092339 (JAK3)    05203 Viral carcinogenesis     101092339 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     101092339 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101092339 (JAK3)    05161 Hepatitis B     101092339 (JAK3)    05162 Measles     101092339 (JAK3)    05169 Epstein-Barr virus infection     101092339 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     101092339 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:fca01001]     101092339 (JAK3) Enzymes [BR:fca01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      101092339 (JAK3) Protein kinases [BR:fca01001]  Non-receptor tyrosine kinases   JAK family [OT]    101092339 (JAK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 Jak1_Phl Kdo ABC1 APH Kinase-like Haspin_kinase Motif Other DBs NCBI-GeneID:  101092339 NCBI-ProteinID:  XP_023102969 Ensembl:  ENSFCAG00000007517 LinkDB All DBs Position A2:complement(13178918..13194986) Genome browser AA seq 1106 aa AA seqDB search MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA SGILPVYHSLFALATEDLSYWYPPSHIFSVEDASTQILLYRLRFYFPNWFGLEKCHRFGL RKDLASAILDLPVLEHLFAQHRNDLVSGRLAVGLSLKEQGECLSLAVLDLARMAREQAQQ PEELLKTVSYKACLPPDLRDLIQGLSFVTRKRIRRTVRRALGRVTACQADRHSLMAKYIM DLERLDPARAAETFLVSLPGAAGGQDAPGLLRVAGDSGIHWSPGGHEALQPFCDFPEIVD ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTSDSRHFFC KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSFLLTVCVQTP LGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLAACWDAGLHVDGVALNLTSCCAPRPK EKSNLIVVRRGCSTPTSSLVWPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR HEAVDGEARETEVLLKVMDAKHRNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSVMVQ EFVRLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GIPMPISTLDPAKKLQFYEERQHLPAPKWMELATLIQQCMAYEPGQRPSFRAIIRDLNSL ITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYGNKNCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPGEVHELMKLCWAP SPQDRPTFSALGPQLDTLWSGSRGVA NT seq 3321 nt NT seq  +upstreamnt  +downstreamnt atggcgcctccaagtgaggagacacccctgatccctcagcgttcctgcagcctctcgtct tcagaggctggtgccctgcacgtgctgctgccccctcggggccccggacccccacaacgc ctgtccttctcctttggggaccattcagctgaagagctatgtgtttgggctgctaaggcc agtggcatcctgcctgtgtaccactccctctttgctctggccacggaggacctgtcctac tggtaccccccgagccacatcttctccgtggaggatgcaagcacccaaatcctgctctac aggctccgcttttacttccccaactggtttgggttggagaaatgccaccgcttcgggcta cggaaggacttggccagtgccatccttgacctgccagtcctggagcacctcttcgcccag caccgaaatgacctggtgagcggccgcctcgccgtgggcctcagtctcaaggagcagggt gaatgtctcagcctggcagtgctggacctggctcggatggcccgtgagcaggctcagcag cctgaggagctgctgaagaccgtcagctacaaggcctgcctgccccccgatctgcgcgac ctgatccagggcctgagcttcgtgacgcggaagcgtatccggaggactgtgcgtcgggcc ctgggccgcgtgaccgcctgccaggctgacaggcactcgctcatggccaagtacatcatg gacctggagaggctggacccggccagggccgccgagaccttcctcgtgagcctccccggg gctgctggtggccaggatgctccggggctgctccgagtggctggtgacagcggcatccac tggagtccgggaggacacgaggccctccagcccttctgcgactttccagaaattgtggac atcagcatcaagcaggctcctcgtgttggccccgccggggagcaccgcctggtcaccgtc accaggacggacaaccagatcctggaggccgagttcccggggctgcccgcggccctgtcc ttcgtggcgctcgtggatggctacttccggctgacttccgactccaggcacttcttctgc aaggaggttgcgccgccgcggctgctggaggaggtggccgaacagtgccacggtcccatc accctggattttgccatcaacaagctcaagaccgggggctcccttcccggctcctatgtt ctccgccgcagcccccaggatttcgacagcttcctcctcactgtctgcgtccagaccccc ctgggtcctgattacaagggctgcctcatccggtgtgaccccacgggaaccttctccctg gctggcctcggccggccccacagcagtcttcgagagctcttggcagcctgctgggatgct gggctgcacgtggatggggttgcgctgaacctcacctcctgctgcgcccccagacccaaa gaaaagtccaacctgatcgtggtgcggagaggttgcagcactcccacatcatcccttgtt tggccccaatcccagtgtcagctgagtcagatgacgtttcacaagatccccgctgacagc ctggagtggcacgagaacctgggtcacgggtccttcaccaagatttaccgaggttgtcgc catgaggctgtggacggggaagcccgggagacagaggtgctactcaaagtgatggatgcc aagcacagaaactgcatggagtccttcctggaagcagcgagcctgatgagccaagtgtcg tatcagcacctcgtgttgctccacggcgtgtgcatggctggagacagtgtcatggtgcag gaatttgtgcgcctgggagccctggatacatatctgcgcaagtctggccacctggtacca gccagctggaagctgcaggtgatcaaacagctggcctatgccctcaactatctggaagac aaaggcctcccccatggcaatgtctcagcccggaaggtgctcttggctcgggagggggct gacgggaacctgcccttcatcaagttgagtgaccctggtgtcagccccactgtgctgagc ctggagatgctcactgacaggatcccctgggtggcccctgagtgtctccaggaggcccgg acccttggcttggaagctgacaagtggggtttcggtgccacagtctgggaagtgttcagc gggatcccgatgcccatcagtaccctggatcctgccaagaagctccagttttacgaggaa cggcagcaccttcccgcccccaagtggatggagctggccaccctgatccaacagtgcatg gcctatgagccaggccagaggccctccttccgtgccatcatccgtgacctgaacagcctc atcacttcagattatgagctcctctcagaccccacacctggtgccttggcgccccgtgat gggctgtggaatggcgcccagctctacgcctgccaggaccctaccatttttgaggagaga catctcaagtacatctcacagctgggcaagggcaactttggcagcgtggagctgtgccgc tatgacccgctgggcgacaacacgggcgccctagtggctgtgaagcagcttcagcacagc gggccagaccagcagagggacttccagcgggagatccagatcctcaaagccctccacagc gacttcattgtcaagtaccgcggtgtcagctatggcccgggccgccagagcctgcggctg gtgatggagtacctgcccagcggctgcctgcgcgacttcctgcagcgacaccgcgcgcgc ctggacgccagccgcctgctcctctacgcctcgcagatctgcaagggcatggagtacctg ggctcccgccgctgcgtgcaccgcgacctggcggcccgtaacatcctggtggagagcgag acgcacgtcaagatcgccgactttggcctcgccaagctgctgccgctcgacaaagactac tacgtggtccgcgagcccggccagagccccatcttctggtacgccccagagtccctctct gacaacatcttctcgcgccaatcggacgtctggagcttcggggtcgtcctgtacgaactt ttcacctacggcaacaagaattgcagcccctcagccgagttcctccggatgatgggatgt gagcgagacgtccccgccctctgccgcctcctggagctgctggctgagggccagaggctg cccgcgcctcctgcctgccccggtgaggttcatgagctcatgaagctgtgctgggccccg agcccgcaagatcggccaacattcagtgccctgggcccccagctggatacactgtggagt ggaagccggggggtagcatag

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