Felis catus (domestic cat): 101094304
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Entry
101094304 CDS
T02385
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X2
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00590
Arachidonic acid metabolism
fca01100
Metabolic pathways
fca01523
Antifolate resistance
fca04726
Serotonergic synapse
fca04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
101094304
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
101094304
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101094304
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101094304
Enzymes [BR:
fca01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
101094304
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
101094304
NCBI-ProteinID:
XP_023099328
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Position
E1:2023632..2034933
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AA seq
664 aa
AA seq
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MGRYRIGVATGAWLFSGSHNRVQLWLVGARGEARLELRLRPARGQEEEFEREVPKDLGPL
QFVKLRKHHSLVDDAWFCDCITVRGPGACEEATFFPCYRWVQGQDVLSLPEGTARLAGDN
ALDVFQKHREKELKERRRLYCWATWKEGLPRTIAAERQDDLPPNSRFHEEKRLDFEWALK
AGALEMVLKRVYTLLSSWSRLEDFDQIFWGQKSDLAERVHHCWRDDELFGYQFLNGANPM
VLRRSASLPSRLVLPSGTEALGAQLERELQSGSLFEADFSLLDGIPANVIRGEKQYLAAP
LVMLQMRPEGKLLPVVIQIQPPSPSCPAPPLFLPSDPPLAWLLAKIWVRNSDFQLHQLQY
HLLNTHLVAEVIAVATMRCLPGLHPVFKLLIPHIRYTLEINTRARSQLISEGGIFDKAVS
TGGGGHVHLLRRAMAQLTYSSLCPPDDLAARGLLGIPSALYAHDALRLWEIIARYVQGIV
RLFYHRDDIVRGDPELQAWCREITEVGLCQAQDRGFPASFQSQSQLCHFLTMCVFTCTAQ
HGAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVKMATVMGSLPDIRQACLQMTITWHLGR
RQPDMVPLGHHKEKYFSSPKAKAVLSQFQTDLENLEREITARNAQVDLPYDYLRPSRIEN
SVTI
NT seq
1995 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatcggcgtggccaccggcgcctggctcttctccgggtcgcacaac
cgcgtgcagctgtggctggtcggggcgcgcggggaggcgcggctggagctgcggctgcgg
ccggcacggggccaggaggaggagttcgagcgcgaagtccccaaggacctggggcccctg
cagttcgtgaagctgcgcaaacaccactcgctggtggacgacgcttggttctgcgactgc
atcaccgtgcgcggccccggagcctgcgaggaggccaccttcttcccctgctaccgctgg
gtgcaaggccaggacgtgctgagcctgcccgagggcaccgcgcgcctggcaggagacaat
gccttggacgtgttccagaagcatcgggagaaagagctgaaggagagacgaagactgtac
tgctgggccacctggaaggaagggttaccccggacgatagcggcagaacgccaggacgat
ctgcctccaaactcgaggttccatgaggaaaagaggctggacttcgagtgggcgctgaag
gcaggggctctggagatggtcctcaagcgcgtttacaccctcctgagctcctggagccgc
ctggaggattttgaccagatcttctggggccagaagagcgacctggctgagagggttcac
cactgctggcgggacgatgaacttttcggctaccagttcctcaacggcgccaaccccatg
gtgctgagacgctccgcctccctgccctctcggctggtgctgccctcggggaccgaggcg
ctgggggcccagctggagagagaactccagagcggttccctgtttgaggctgacttcagc
ctgctggacggaatcccggccaacgtgatccgaggagagaagcagtacctggccgccccc
ctcgtgatgctccagatgcggcccgaggggaagctgctgcccgtggtcatccagatccag
ccccccagccccagctgccccgcgcccccgctgttcctgccctcggatcccccgctcgcc
tggctcctggcaaagatctgggtccgcaattccgatttccaactgcaccagctccagtat
catctgctcaacactcacctggtggccgaggtcatcgccgtggccaccatgaggtgcctc
ccagggctgcaccccgtcttcaagctcctgatcccgcacatccgctataccttggaaatc
aacacccgggccagatcccagctcatctcggaaggaggaatatttgataaggcggtgagc
actggcggagggggccacgtgcacttgctccgtcgggccatggcccagctgacctacagc
tccctctgtcctcctgacgacctggctgcgcggggcctgctgggaatcccaagtgccctc
tacgcccacgacgccctacggctctgggagatcattgcccggtacgtgcagggcatcgtc
cgccttttctaccacagggacgacatcgtgagaggggaccctgagctgcaggcctggtgc
cgggagatcaccgaggtggggctgtgccaggcccaggaccgaggtttccccgcctccttc
cagtcccagagtcagctctgtcatttccttacgatgtgcgtcttcacttgcactgcccag
cacggggccatcaaccagggccagctggactggtacgcctgggtccctaacgccccgtgc
accatgcggatgcccccacccacgaccaaggaagacgtgaagatggccacagtgatgggc
tcactacctgacatccgacaggcctgtcttcaaatgaccatcacgtggcacctgggtcgc
cgccagccagacatggtacctctggggcaccacaaagaaaagtatttctcaagccccaag
gccaaggctgtactaagccaattccaaacagatctggaaaacttagaaagagagatcaca
gcccggaatgcacaagtggacctgccctacgactacctgaggcccagccgcatagagaac
agtgttaccatctga
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