Felis catus (domestic cat): 101095973
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Entry
101095973 CDS
T02385
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca04137
Mitophagy - animal
fca04140
Autophagy - animal
fca04141
Protein processing in endoplasmic reticulum
fca04210
Apoptosis
fca04932
Non-alcoholic fatty liver disease
fca05010
Alzheimer disease
fca05012
Parkinson disease
fca05014
Amyotrophic lateral sclerosis
fca05020
Prion disease
fca05022
Pathways of neurodegeneration - multiple diseases
fca05160
Hepatitis C
fca05162
Measles
fca05168
Herpes simplex virus 1 infection
fca05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101095973 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101095973 (EIF2AK3)
04137 Mitophagy - animal
101095973 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
101095973 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
101095973 (EIF2AK3)
05162 Measles
101095973 (EIF2AK3)
05168 Herpes simplex virus 1 infection
101095973 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
101095973 (EIF2AK3)
05012 Parkinson disease
101095973 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
101095973 (EIF2AK3)
05020 Prion disease
101095973 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
101095973 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101095973 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101095973 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101095973 (EIF2AK3)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101095973 (EIF2AK3)
Protein kinases [BR:
fca01001
]
Serine/threonine kinases: Other
PEK family [OT]
101095973 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
101095973
NCBI-ProteinID:
XP_019683111
UniProt:
M3WHG0
LinkDB
All DBs
Position
A3:complement(101656074..101725320)
Genome browser
AA seq
1114 aa
AA seq
DB search
MERATRPGPLVRALLLLQLLLGLAAGTVAAGRAPDLPAPKVEAAFGLGAAAAPTSAARVP
AAGAVAAAEVTVEDAEAVPAAAVEQEPREPEPDDEAELQPRGRSLVIISTLDGRIAALDP
ENRGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVES
LLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDNDEMEQEDILLLQRS
QKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGNKEGSKIISDVEEQ
EAAMMDTVIKVSVADWKVMAFNKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLFDDTSY
ASNDEVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVNNEY
AIVPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYY
LPYYKRERSKRSTQITVRFLDNPNYNKNIRKKDPVLLLHWWKEIVGTILFCIIATTFIVR
RLFHPHPHRQRKESETQCQTESKYDSVSGDAKDSSWNDIKNSGYISRYLTDFEPVQCLGR
GGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLDHPGIVRYFNAWLEA
PPEKWQEKMDEIWLKDESTDWPLSSPSPVDGPSVKICRMDPFSTKEHIEIIAPSSQRRSF
SVGISCGQTSSSESQFSPLELSGTNHGDTSESVDAAYNLQDSCLTECDMEDGTMDGNEEG
HSFELCPSEASLYGRSRERTSSSIVFEDSGCDNASRKEEHKTDRLHIGNHCANKLTPFKH
SSSKSSSEPTFSISPPRPTTLSLDLTKNTAEKLQPSSPKVYLYIQMQLCRKENLKDWMNS
RCTIEERERSMCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTVDDVVKVGDFGLVTAM
DQDEEEQMVLTPMPACARHTGQVGTKLYMSPEQIHGSNYSHKVDIFSLGLILFELLYPFG
TQMERVRILTDVRNLKFPPLFTQKYPREYVMVQDMLSPSPMERPEATNIIENAVFEDLEF
LGKTVLRQRSRSMSSSGTKHSRHCSSSWSPLPST
NT seq
3345 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccacccgcccggggccgctcgtgcgggcgctgctgctgctgcagctgctg
ctggggctcgcggctggcacggtggccgcagggcgcgcccccgacctccccgcgccgaag
gtggaggcggcgttcggcctgggcgccgcggccgctcccacttcagcagcgcgggtgccg
gctgcgggggccgtggctgcggccgaggtgacggtggaggacgccgaagcagtgccggcg
gccgcggtcgagcaggagccgcgggagccggagcccgacgacgaggccgagctacagccg
cgaggcagatcattagtgatcatcagcactttagatgggcgaattgctgccttggatcct
gagaatcgtggtaaaaaacagtgggatttggacgtgggatccggctccttggtttcatcc
agcctcagcaaaccagaggtatttgggaataagatgatcattccttccctggatggagac
ctctttcagtgggaccgggaccgtgagagcatggaaactgttccttttacagttgaatca
cttcttgaatcttcttataaatttggagacgatgttgttttggttggaggaaagtctctc
actacatacggactcagtgcatatagtggaaaggtgaggtatatctgctcagctctgggt
tgtcgccagtgggataatgatgaaatggaacaagaagacatcctgcttctgcagcgctcc
cagaaaaccgttagagctgttggacctcgcagtggcaatgagaagtggaatttcagtgtt
ggccactttgaacttcggtatattccagacatggaaactagagccggatttattgaaagc
accttaaagcccagtgggaacaaagaagggtctaaaattatttcagatgtggaagaacag
gaagctgccatgatggacacagtgataaaggtgtcggttgcagactggaaggttatggcg
tttaataagaagggaggacatctggaatgggaataccagttttgtactcccattgcatct
gcctggttggttaaggacggaaaagtcattcccatcagtctttttgatgatacaagttat
gcatctaatgatgaagttttagaagatgaagaagacattgtagaagctgctcgaggagcc
acagaaaacagcgtttacttgggaatgtacagaggtcagctgtatctgcagtcatcagtc
agaatttcagaaaagtttcctacaagtcccaaggccttggaatctgtcaataatgaatat
gcaattgttcctttgccaacaatcaaatggaagcccttaattcattccccatccagaact
cctgtcttggtagggtctgatgaattcgacaaatgtcttagcaacgataagttttctcac
gaagagtacagcaacggtgcgctttcaatcttgcaatacccatatgataatggttattac
ctaccatactacaagagggagaggagcaaacggagcacacagatcacagtccgatttctc
gataacccaaattacaacaagaacattcgcaaaaaggatcccgttctcctcttacactgg
tggaaagaaatagtcggaactattctattttgtatcatagcaacaacttttatcgtgcgt
aggcttttccatcctcatcctcacagacaaaggaaggaatcggaaactcagtgtcagact
gaaagtaaatacgattctgtaagtggagacgccaaggacagtagctggaatgacataaaa
aattctggatatatatcgcgatatctaacagattttgagccggttcagtgcctgggacgc
ggtgggtttggagttgtctttgaagccagaaataaagttgatgactgcaattatgctatc
aagagaatccgtctccccaacagggaattggctcgggaaaaggtaatgcgagaagttaaa
gccttagccaagcttgaccatccaggaattgtgagatatttcaatgcttggttggaggca
ccaccagagaagtggcaagaaaaaatggatgaaatctggctgaaagatgaaagcacagac
tggccactcagctctcctagtccagtggatggaccatccgttaaaatatgcagaatggac
cctttctctacaaaggaacatattgagatcatagctccttcttcacaaaggaggtctttt
tcagtagggatttcctgtggccagacaagttcatctgagagccagttctctccactggaa
ttatcaggaacgaaccacggagataccagtgaatcagtggatgcagcctacaacctccag
gacagttgccttacagagtgtgatatggaagacggtaccatggacggcaatgaggagggg
cactcctttgaactttgtccttctgaagcttctctttatggaaggtcaagggagcgaaca
tcctcttctatagtgtttgaagactctggctgcgataatgcatccaggaaagaagagcac
aaaactgaccgcctgcatattggcaaccattgtgctaataaactgactccttttaagcat
tccagtagcaaatcttcttccgaacctaccttctctatttctcctccaagaccgaccact
ttgagtttagatctcactaaaaacactgcagaaaagctccagcccagttcaccgaaggtg
tatctttacattcagatgcagctgtgcagaaaggaaaacctcaaagactggatgaacagt
cggtgcaccatagaggagagagagaggagcatgtgtctgcacatcttcctgcagatcgca
gaggccgtagagtttctgcacagtaaagggctcatgcacagggacctcaagccttccaac
atattctttacagtggacgatgtggtcaaggtcggagactttggactagtgactgcaatg
gaccaggacgaggaagagcagatggttctgaccccaatgccagcgtgtgccagacacaca
ggacaagtagggaccaaactgtatatgagcccagagcagattcatggaagcaactactct
cataaagtggacatcttttctttaggcctcattctgtttgaactgctgtacccattcggc
actcagatggagagagtcaggatcttaactgatgtaagaaatctcaaatttccaccactg
tttactcagaaatatcctcgtgagtatgtgatggttcaagacatgctctctccatccccc
atggaacggcctgaagctaccaacattattgaaaatgctgtatttgaagacttggaattt
ctaggaaaaactgtactcagacagaggtctcgctccatgagttcatcaggaacaaaacat
tcaagacactgcagcagctcctggagccctttgccaagcacttag
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