Felis catus (domestic cat): 101098805
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Entry
101098805 CDS
T02385
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X2
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca04064
NF-kappa B signaling pathway
fca04380
Osteoclast differentiation
fca04650
Natural killer cell mediated cytotoxicity
fca04658
Th1 and Th2 cell differentiation
fca04659
Th17 cell differentiation
fca04660
T cell receptor signaling pathway
fca05135
Yersinia infection
fca05166
Human T-cell leukemia virus 1 infection
fca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
fca05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
101098805 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101098805 (LCK)
04660 T cell receptor signaling pathway
101098805 (LCK)
04658 Th1 and Th2 cell differentiation
101098805 (LCK)
04659 Th17 cell differentiation
101098805 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
101098805 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101098805 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101098805 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
101098805 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
101098805 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101098805 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
fca03036
]
101098805 (LCK)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101098805 (LCK)
Protein kinases [BR:
fca01001
]
Non-receptor tyrosine kinases
SRC family
101098805 (LCK)
Chromosome and associated proteins [BR:
fca03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
101098805 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
SH3_16
Motif
Other DBs
NCBI-GeneID:
101098805
NCBI-ProteinID:
XP_003989862
Ensembl:
ENSFCAG00000012482
UniProt:
A0A2I2UG73
LinkDB
All DBs
Position
C1:24532648..24553712
Genome browser
AA seq
509 aa
AA seq
DB search
MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKATLPMRNGSDVRDPLVTYEGSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDKGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPPGIKLTINKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKER
PEERPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtagctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtgtgt
gagaactgccattacccgatagtcccactggatggcaaggccacgctgcccatgcggaat
ggctctgatgtgagggatccactagttacctacgaaggctccaatcccccagcctcacca
ttgcaagacaacctggttattgctctgcacagctatgagccctctcacgatggagacctg
ggcttcgagaagggtgaacagctccgtatcctggagcagagcggcgagtggtggaaggcg
cagtccctgaccacgggccaggaaggtttcatccccttcaacttcgtggccaaagcgaac
agcctggagcccgaaccctggttcttcaagaacctgagccgcaaggacgcggaacggcag
ctcctggcgcccgggaacacgcacggctccttcctgatccgggagagcgagagcaccgcg
ggatcgttttcactgtccgtgcgggacttcgaccagaaccagggagaggtggtgaaacat
tacaagatccgtaacctggacaaaggcggcttctacatctccccccgcatcacttttcct
ggcctgcacgagctggtccgccattacaccaatgcttcggacgggctgtgcacgcggttg
agtcgcccctgccagacccagaagccccagaagccttggtgggaggacgagtgggaggtt
cccagggagacgctgaagctggtggagcggctgggggctggccagttcggggaggtgtgg
atgggatactacaacgggcacacaaaggtggcagtgaagagcctgaagcagggcagcatg
tcccccgacgccttcctggccgaggccaacctcatgaagcagctacaacaccagaggctg
gtccggctctacgcggtggtcacccaggagcccatctacatcatcacggaatacatggag
aatgggagcctggtggatttcctcaagacccctccaggcatcaagttgaccatcaacaaa
ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagaacggaattac
atccaccgtgacctgagggctgccaacatcctggtgtcggacaccctgagctgcaagatt
gcagactttggcctagcacgcctcattgaggacaatgagtacacagccagggagggggcc
aagtttcccattaagtggacagcaccagaagccattaactacgggacattcaccatcaag
tcggacgtgtggtcttttgggatcctactgacggagattgtcacccatggccgcatccct
tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggtg
cgacctgacaactgcccagaggagctataccacctcatgatgctgtgctggaaggagcgg
ccagaggaacggcccacctttgactacctgcgcagcgtgctggaggacttcttcacggcc
acagagggccagtaccagccccagccctga
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