Felis catus (domestic cat): 101101086
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Entry
101101086 CDS
T02385
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca04010
MAPK signaling pathway
fca04020
Calcium signaling pathway
fca04151
PI3K-Akt signaling pathway
fca05200
Pathways in cancer
fca05216
Thyroid cancer
fca05223
Non-small cell lung cancer
fca05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101101086 (RET)
04020 Calcium signaling pathway
101101086 (RET)
04151 PI3K-Akt signaling pathway
101101086 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101101086 (RET)
05230 Central carbon metabolism in cancer
101101086 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
101101086 (RET)
05223 Non-small cell lung cancer
101101086 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101101086 (RET)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101101086 (RET)
Protein kinases [BR:
fca01001
]
Receptor tyrosine kinases (RTK)
RET family
101101086 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD1
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
101101086
NCBI-ProteinID:
XP_023096467
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All DBs
Position
D2:complement(49769512..49821275)
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AA seq
1117 aa
AA seq
DB search
MAKATATAGAARLRLLLLLPLLGEAPLGLYFARDAYWEKLYVDQPAGMPLLYVHALRDMP
EEVPAFRLGQHLYGIAYRARLHENEWIRIEEDTGLLYLNRSLDHSTWDKLSIRNGGFPVL
TIYLQVFLSPTSLREGECQWPSCARVYFSFVNTSFPACGSLKPRELCFPETSVSFRIREN
RPPGTFHQFRLLPVQFLCPNISVAYRLLEGENLPFHCAPDSLEVSTRWPLDRELREKYEL
VAACTVRVGARKEEVVMVPFPVTVYDEDDSAPTFLGGIDTASAVVEFKRKEGTVVAKIRV
FDADVVPASGELLKRYTNTLLSGDAWVLQTFRIEHSPNETLAQANGSFVRATVHDYRLVL
NRSLPISENRSLQLTVLVNDSDFQGPGEGTLFLHFNVSVLPVSLHLPSTYTFTVSRRARR
FAQIGKVCVENCQEFSGIHVQYRLQLSSTNCSVLGVVTSAEDTSGNLFVNDTEALQRPDC
SQLRYTVVAADRPTRKQTQALLVVTVEGTYVAEEPGCPLSCAVSKRRPECEECGGLGSLT
GRCEWRQGDGKGITRNFSTCSPSIKTCPDGHCDAVESRNVNICPQDCLRGGSIIGGHEPG
ERWGIKAGFGICNCFPEEKKCFCEPEDSQEPLCDELCRTVIAAAVLFSFVVSMLLSTFCI
HRYHKNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSMDSMENQVSVDAFKIPEDPKW
EFPRKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFN
LLKQVNHPHVIKLYGACSQDGPLFLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRSSSY
LDNPEERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSR
DVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP
ERLFNLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKNRDYLD
LAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPEESPVPL
TRADGTNTVCPRYANDSVYANWMVSPSAAQLMDAFDS
NT seq
3354 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggcgacggccggcgccgcgaggctgcggttgctgctgctgctgccg
ctgctcggcgaagctccgctgggactctacttcgccagggatgcttactgggagaaactc
tacgtggaccagccagctggcatgcccctgctctacgtccatgccctgcgggacatgccg
gaggaggtgcccgccttccgcctgggccagcacctctacggcatcgcctaccgtgcaaga
ctgcatgagaacgaatggattcgcatcgaggaggacactggccttctctaccttaaccgg
agcctggatcacagcacctgggacaagctcagcatccgcaatggcggcttccctgtgctc
accatctacctccaggtcttcctgtcacctacatccctgcgtgagggcgagtgccaatgg
cccagctgtgcccgtgtgtacttctcctttgtcaacacctccttcccggcttgtggttcc
ctcaaaccccgggagctctgctttcctgagacaagtgtctccttccgcatcagagagaat
aggcctcctggcactttccaccagttccgcctgctgcctgtgcagttcctctgtcccaac
atcagcgtggcctacaggctcctagaaggtgagaacctgcccttccactgcgccccggac
agcctggaagtgagcacgcgctggcccctggatcgcgagctgcgggagaagtacgagctg
gtggctgcttgcacggtgcgcgtcggcgcacgcaaggaggaggtggtgatggtgcccttc
cccgtgaccgtgtatgatgaggacgactcggcgcccaccttcctcgggggcatcgacacc
gccagcgctgtggtggagttcaagaggaaggagggcactgtggtggccaaaatacgtgtc
ttcgatgcagacgtggtgccagcatccggggagctcctgaagcgatacacaaacacacta
ctctctggggatgcctgggtcctccagacattccgtatcgagcactcccccaacgagacc
ttggcccaggccaacggcagctttgtgcgggcaactgtgcatgactacaggctggttctc
aaccggagcctccccatctcggagaaccgctccctgcagctgaccgtgctggtcaatgac
tcggacttccagggccccggggagggcaccctcttcctccacttcaacgtgtccgtgctg
cctgtcagcttgcacttgcccagcacctacaccttcactgtgagcaggcgggcccgccgc
tttgcccagattgggaaagtctgtgtggaaaactgccaagagttcagcggcatccacgtg
cagtacaggctgcagctctccagcaccaactgcagtgtcctgggggtggtcacctcagcc
gaggacacctcagggaaccttttcgtgaacgacacagaagccctgcagcggcccgattgc
tctcaactccggtacacggtagtggctgccgaccggccaacccgcaagcagacccaggcc
ctgctggttgtcaccgtggaggggacatatgtggctgaggagccaggctgccccctgtcc
tgtgcagtcagcaagagacgccctgaatgtgaggagtgcggcggcctgggctctctgacg
ggcaggtgcgagtggagacagggagatggcaaaggaatcaccaggaacttctccacctgc
tcccccagcatcaagacctgccccgacggccactgtgatgccgtggagagcagaaatgtc
aacatctgcccccaggactgcctccggggcggcagcatcattggtgggcatgagccaggg
gagcgctgggggattaaagctggcttcggtatctgcaactgtttcccagaggagaagaag
tgcttctgcgaacctgaagacagccaggagccgctgtgtgacgagctctgccgcacggtg
atcgcggccgctgtgctcttctccttcgtcgtctccatgctgctctccaccttctgcatc
caccgctaccacaagaacgcccacaagccacccattgcctctgctgagatgaccttccgc
cggcctgcccaggccttcccggtcagctactcctcgtccggcgcccgccggccctctatg
gactccatggagaaccaggtctctgtggacgccttcaagatcccggaggatccaaagtgg
gaattccctcgaaagaacttggttcttgggaaaaccctgggagaaggcgaatttggaaaa
gtggttaaggcgacagccttccggctgaaaggcaaagcagggtacacaactgtggccgtg
aagatgctgaaagagaacgcttccccaagtgagctgcgggacctgctgtcagagttcaac
ctcctgaagcaggtcaaccacccacatgtcatcaagctgtacggggcctgcagccaggac
ggcccgctcttcctcattgtggagtatgccaagtacggttccctgcggggcttcctccga
gagagccgcaaggcggggcccggctacgtgggcagcggaggcagccgcagctccagctac
ctggacaaccccgaggagcgggccctgaccatgggcgacctcatctccttcgcctggcag
atctctcgggggatgcggtacctggctgagatgaagcttgtccatcgggacttggcagcc
agaaatgtcctggtagctgaggggcggaagatgaagatttcggattttggcctgtcccga
gacgtttatgaagaggattcctatgtgaagaggagcaagggtcggattccagtcaaatgg
atggcaattgagtctcttttcgatcatatctacaccacccaaagtgatgtgtggtccttt
ggtgtcctgctgtgggagattgtgactctggggggcaacccctaccctgggatccctccg
gagcggcttttcaacctcctgaagacaggctaccggatggagaggcccgacaactgcagt
gaggagatgtacggtctcatgctgcagtgttggaagcaggaaccagacaagaggccagtg
tttgctgacatcagcaaagacctggaaaagatgatggttaagaacagagactacttggac
ctggctgcctccaccccatccgactccctgctttatgacgacggcctctcggaggaggag
acgcccctggtggactgtaataatgctcccctccctcgagccctcccctccacgtggatt
gaaaacaaactctatggcatgtcagacccgaactggcctgaagagagtcctgtaccactc
acgagagctgatggcactaacactgtgtgtccaagatatgcaaatgatagtgtatatgct
aactggatggtttcaccctcagcggcacaattaatggacgcatttgatagttaa
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