Felis catus (domestic cat): 101101375 Help Entry 101101375         CDS       T02385                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism fca  Felis catus (domestic cat) Pathway fca00230   Purine metabolism fca01100   Metabolic pathways fca01522   Endocrine resistance fca04015   Rap1 signaling pathway fca04020   Calcium signaling pathway fca04022   cGMP-PKG signaling pathway fca04024   cAMP signaling pathway fca04062   Chemokine signaling pathway fca04072   Phospholipase D signaling pathway fca04081   Hormone signaling fca04082   Neuroactive ligand signaling fca04114   Oocyte meiosis fca04211   Longevity regulating pathway fca04213   Longevity regulating pathway - multiple species fca04261   Adrenergic signaling in cardiomyocytes fca04270   Vascular smooth muscle contraction fca04371   Apelin signaling pathway fca04540   Gap junction fca04611   Platelet activation fca04713   Circadian entrainment fca04714   Thermogenesis fca04720   Long-term potentiation fca04723   Retrograde endocannabinoid signaling fca04724   Glutamatergic synapse fca04725   Cholinergic synapse fca04727   GABAergic synapse fca04750   Inflammatory mediator regulation of TRP channels fca04911   Insulin secretion fca04912   GnRH signaling pathway fca04913   Ovarian steroidogenesis fca04914   Progesterone-mediated oocyte maturation fca04915   Estrogen signaling pathway fca04916   Melanogenesis fca04918   Thyroid hormone synthesis fca04921   Oxytocin signaling pathway fca04923   Regulation of lipolysis in adipocytes fca04925   Aldosterone synthesis and secretion fca04926   Relaxin signaling pathway fca04927   Cortisol synthesis and secretion fca04928   Parathyroid hormone synthesis, secretion and action fca04934   Cushing syndrome fca04935   Growth hormone synthesis, secretion and action fca04970   Salivary secretion fca04971   Gastric acid secretion fca04972   Pancreatic secretion fca04976   Bile secretion fca05032   Morphine addiction fca05142   Chagas disease fca05146   Amoebiasis fca05163   Human cytomegalovirus infection fca05166   Human T-cell leukemia virus 1 infection fca05200   Pathways in cancer fca05207   Chemical carcinogenesis - receptor activation fca05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:fca00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     101101375 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     101101375 (ADCY1)    04371 Apelin signaling pathway     101101375 (ADCY1)    04020 Calcium signaling pathway     101101375 (ADCY1)    04072 Phospholipase D signaling pathway     101101375 (ADCY1)    04024 cAMP signaling pathway     101101375 (ADCY1)    04022 cGMP-PKG signaling pathway     101101375 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     101101375 (ADCY1)    04081 Hormone signaling     101101375 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     101101375 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     101101375 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101101375 (ADCY1)    04062 Chemokine signaling pathway     101101375 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     101101375 (ADCY1)    04923 Regulation of lipolysis in adipocytes     101101375 (ADCY1)    04912 GnRH signaling pathway     101101375 (ADCY1)    04913 Ovarian steroidogenesis     101101375 (ADCY1)    04915 Estrogen signaling pathway     101101375 (ADCY1)    04914 Progesterone-mediated oocyte maturation     101101375 (ADCY1)    04921 Oxytocin signaling pathway     101101375 (ADCY1)    04926 Relaxin signaling pathway     101101375 (ADCY1)    04935 Growth hormone synthesis, secretion and action     101101375 (ADCY1)    04918 Thyroid hormone synthesis     101101375 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     101101375 (ADCY1)    04916 Melanogenesis     101101375 (ADCY1)    04925 Aldosterone synthesis and secretion     101101375 (ADCY1)    04927 Cortisol synthesis and secretion     101101375 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101101375 (ADCY1)    04270 Vascular smooth muscle contraction     101101375 (ADCY1)   09154 Digestive system    04970 Salivary secretion     101101375 (ADCY1)    04971 Gastric acid secretion     101101375 (ADCY1)    04972 Pancreatic secretion     101101375 (ADCY1)    04976 Bile secretion     101101375 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     101101375 (ADCY1)    04727 GABAergic synapse     101101375 (ADCY1)    04725 Cholinergic synapse     101101375 (ADCY1)    04720 Long-term potentiation     101101375 (ADCY1)    04723 Retrograde endocannabinoid signaling     101101375 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101101375 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     101101375 (ADCY1)    04213 Longevity regulating pathway - multiple species     101101375 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     101101375 (ADCY1)    04714 Thermogenesis     101101375 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101101375 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     101101375 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101101375 (ADCY1)    05163 Human cytomegalovirus infection     101101375 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     101101375 (ADCY1)    05142 Chagas disease     101101375 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     101101375 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     101101375 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     101101375 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     101101375 (ADCY1) Enzymes [BR:fca01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      101101375 (ADCY1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6688 Motif Other DBs NCBI-GeneID:  101101375 NCBI-ProteinID:  XP_006929124 LinkDB All DBs Position A2:62038742..62150888 Genome browser AA seq 1132 aa AA seqDB search MAGAPRGRGGGGGGGGGGAGEPGGAERAARPGGRRGLRACDEEFACPELEALFRGYTLRL EQAATLKALAVLSGLAGALALAELLGAPGPAAGLARGSHPAHCVLFLALLVVTNVRSLQV PQLQQVGQLALLFSLTFALLCCPFALGRPAGTLAGAASGPATADQGVWQLLLVTFVSYAL LPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLSVNMYGVFVRILAE RSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYI QRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYC VSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQY DVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKAHNIETFFI VPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVLTCEDDDKR RALRTASEKLRNRSSFSANAVYTTPGTRVNRYIGRLLEARQTELEMADLDFFTLKYKQAE RERKYHQLQDEYFTSAVVLALVLAALFGLVYLLIIPQNLVLLLLLAFCICFLVACVLYLH VTRVQCFPGCLTIQIRTVLCIFVVVLIYSVAQGCVVGCLPWSWSSTPNGSLVVLTPSGRN AVLPAAPCESAPHALLCGLVGTLPLAVFLRVSSLPKMILLFVLTTSYILVLELSGYTRAP GGGVASGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMERVKLDNKR ILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIELDGNNMGVECLR LLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTTGTKAKKGISSHLSTLADFA IEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQ GRIQVTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQARERKVCGYGR AGLQGRLGTGPPPVSSMAGLPVRAGMGALQGSGLPPCPHGQHLPPGAAGKEA NT seq 3399 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggaggcggcggcggaggcggaggcggcgcgggc gagcccgggggcgcggagcgggcggcccggccgggcggccggcgcgggctgcgggcgtgc gacgaggagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctg gagcaggcggctacgctgaaggcgctggcggtgctcagcgggctggcgggcgcgctggcg ctggccgagctgctgggcgcgccggggcccgcggccggcctggcccggggctcgcacccc gcgcactgcgtgctcttcctggcgctgctcgtggtcaccaacgtgcgctcgctgcaggtg ccccagctgcagcaggtcggccagctggcgctgctcttcagcctcaccttcgcgctgctg tgctgccccttcgcgctcggccgccccgcggggaccctcgccggcgccgcttcggggccg gcgaccgccgaccagggcgtgtggcagctcctgctggtcaccttcgtgtcctatgccctg ctgcccgtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcgcacttg ctggtcacggccaccttggtacccgccaagcgcccgcgtctctggaggacgcttggtgcc aacgccctgctcttcctcagcgtgaacatgtatggggtgtttgtgcgcatcctggctgag cgctcccagcggaaagccttcctgcaagcccggaactgcatcgaagatcggctgaggctg gaggatgagaacgagaagcaggagcggctgctcatgagccttctgccccggaatgttgcc atggagatgaaggaggacttcctgaagccccccgagaggattttccacaagatttacatc cagcggcatgacaacgtgagcatcctctttgcggacattgtgggcttcacgggcctggca tcgcagtgcacggcacaggagctggtgaagctcctcaacgagctgttcggcaagtttgat gaactggccacggagaatcactgtcgccgcatcaagatcctaggggactgttactactgt gtgtctggcctcacccagcccaagaccgaccacgcccactgctgcgtggagatgggcctg gacatgatcgacaccatcacgtctgtggccgaggccaccgaggtggacctgaacatgcgc gtggggctgcacacaggcagggtcctctgcggggtcctgggcctgcgcaagtggcagtac gacgtgtggtccaacgacgtgactctggccaacgtcatggaggcagccggcctacctggg aaggtccacatcacgaagacgaccctagcgtgcctgaacggggactacgaggtggagccg ggtcacggacatgagaggaacagttttctgaaagctcacaacatcgagaccttctttatc gtgccgtcacatcggcggaagatatttccagggctgatcctctctgacataaaaccagcc aagaggatgaagttcaagaccgtgtgctacctgctcgtgcagctgatgcactgtcggaag atgttcaaggcagagatcccgttctctaacgtcctgacgtgtgaggacgacgacaagcgg agggcgctgagaaccgcgtcggagaaactgcgaaaccgctcttcgttctccgcaaacgcc gtctacaccaccccgggcacgcgcgtcaacaggtacatcggccgcctcctggaagcgcgc cagacggagctggagatggcggacttggacttcttcaccctcaagtacaagcaggctgag cgggagcgcaagtaccaccagctccaggacgagtattttaccagcgccgtcgttctggcc ctcgtcctggccgccttgttcggcctcgtctacctgctcatcatcccacagaacctggtc ctcctgctgctgctggccttctgtatctgcttcctggtggcctgcgtcttgtacctgcac gtcacccgggtccagtgttttccagggtgcctgacgattcagatccgtaccgtcttgtgt atcttcgtcgtggtcttaatctactccgtggcccaaggatgtgtggtgggctgcctgccc tggtcctggagctccacccccaacgggtccctggtggtcctgacgcccagcggccgcaac gccgtgctgcctgccgcgccctgtgagtcggcgccccacgccctgctctgcggccttgtg ggtaccctcccgctggctgtcttcctgcgggtgtcctccctgcccaaaatgatcctgctc tttgtgctcacgacgtcctacatcctggtcctggagctcagcggctacaccagggccccc gggggcggcgtggcgtcggggcgcagtttcgagccgatcatggccatcctgctgttttcc tgcaccctggccctgcacgcccgtcaggtggacgtcaagctgcggctggactacctctgg gcagcacaggcagaggaggagagagatgacatggagagggtgaagttggacaacaagagg attctcttcaacctcctgccggcccacgtggctcagcacttcctcatgtccaacccccgc aacatggacctgtactaccagtcctactcacaggtgggcgtcatgtttgcttccatcccc aacttcgacgacttctacatcgagctggacggcaacaacatgggggtggagtgtctgcgt ctcctgaacgagatcatcgcagacttcgacgagctcatggacaaagacttttacaaggac ttggagaagatcaagaccatcgggagcacctacatggccgctgtggggctggcgcccacc actgggaccaaggccaagaagggcatctcctcccacctgagcacactggctgacttcgcc atcgagatgttcgacgtcctggatgaaatcaactaccagtcttacaacgactttgtgctc cgtgtgggcatcaacgtaggccctgtggtggccggggtgatcggggctcggaggccgcag tacgacatctgggggaacacagtcaacgtggccagtcggatggacagcaccggcgtccag ggcagaatccaggtgactgaggaggttcaccggctgctgcgccgggggacctaccgcttc gtgtgccgcgggaaggtcagcgtcaagggcaagggtgagatgctgacgtacttcctggaa ggcaggacggatggaaacggctcccaagccagggagcggaaagtgtgtggctacgggcga gccggcctccagggcagactgggcacgggcccacccccggtgtcctccatggccggcctc ccggtcagagccgggatgggggctctgcagggctcagggctccccccctgcccccacggc cagcacctgccccccggagcagctgggaaggaggcttag

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