Felis catus (domestic cat): 493687 Help Entry 493687            CDS       T02385                                  Symbol IL6 Name (RefSeq) interleukin-6 precursor   KO K05405   interleukin 6 Organism fca  Felis catus (domestic cat) Pathway fca01521   EGFR tyrosine kinase inhibitor resistance fca01523   Antifolate resistance fca04060   Cytokine-cytokine receptor interaction fca04061   Viral protein interaction with cytokine and cytokine receptor fca04066   HIF-1 signaling pathway fca04068   FoxO signaling pathway fca04151   PI3K-Akt signaling pathway fca04218   Cellular senescence fca04620   Toll-like receptor signaling pathway fca04621   NOD-like receptor signaling pathway fca04623   Cytosolic DNA-sensing pathway fca04625   C-type lectin receptor signaling pathway fca04630   JAK-STAT signaling pathway fca04640   Hematopoietic cell lineage fca04657   IL-17 signaling pathway fca04659   Th17 cell differentiation fca04668   TNF signaling pathway fca04672   Intestinal immune network for IgA production fca04931   Insulin resistance fca04932   Non-alcoholic fatty liver disease fca04933   AGE-RAGE signaling pathway in diabetic complications fca04936   Alcoholic liver disease fca05010   Alzheimer disease fca05020   Prion disease fca05022   Pathways of neurodegeneration - multiple diseases fca05132   Salmonella infection fca05133   Pertussis fca05134   Legionellosis fca05135   Yersinia infection fca05142   Chagas disease fca05143   African trypanosomiasis fca05144   Malaria fca05146   Amoebiasis fca05152   Tuberculosis fca05161   Hepatitis B fca05162   Measles fca05163   Human cytomegalovirus infection fca05164   Influenza A fca05166   Human T-cell leukemia virus 1 infection fca05167   Kaposi sarcoma-associated herpesvirus infection fca05168   Herpes simplex virus 1 infection fca05169   Epstein-Barr virus infection fca05171   Coronavirus disease - COVID-19 fca05200   Pathways in cancer fca05202   Transcriptional misregulation in cancer fca05321   Inflammatory bowel disease fca05323   Rheumatoid arthritis fca05332   Graft-versus-host disease fca05410   Hypertrophic cardiomyopathy fca05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:fca00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     493687 (IL6)    04668 TNF signaling pathway     493687 (IL6)    04066 HIF-1 signaling pathway     493687 (IL6)    04068 FoxO signaling pathway     493687 (IL6)    04151 PI3K-Akt signaling pathway     493687 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     493687 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     493687 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     493687 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     493687 (IL6)    04620 Toll-like receptor signaling pathway     493687 (IL6)    04621 NOD-like receptor signaling pathway     493687 (IL6)    04623 Cytosolic DNA-sensing pathway     493687 (IL6)    04625 C-type lectin receptor signaling pathway     493687 (IL6)    04659 Th17 cell differentiation     493687 (IL6)    04657 IL-17 signaling pathway     493687 (IL6)    04672 Intestinal immune network for IgA production     493687 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     493687 (IL6)    05202 Transcriptional misregulation in cancer     493687 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     493687 (IL6)    05161 Hepatitis B     493687 (IL6)    05171 Coronavirus disease - COVID-19     493687 (IL6)    05164 Influenza A     493687 (IL6)    05162 Measles     493687 (IL6)    05168 Herpes simplex virus 1 infection     493687 (IL6)    05163 Human cytomegalovirus infection     493687 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     493687 (IL6)    05169 Epstein-Barr virus infection     493687 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     493687 (IL6)    05135 Yersinia infection     493687 (IL6)    05133 Pertussis     493687 (IL6)    05134 Legionellosis     493687 (IL6)    05152 Tuberculosis     493687 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     493687 (IL6)    05144 Malaria     493687 (IL6)    05142 Chagas disease     493687 (IL6)    05143 African trypanosomiasis     493687 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     493687 (IL6)    05321 Inflammatory bowel disease     493687 (IL6)    05332 Graft-versus-host disease     493687 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     493687 (IL6)    05020 Prion disease     493687 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     493687 (IL6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     493687 (IL6)    05410 Hypertrophic cardiomyopathy     493687 (IL6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     493687 (IL6)    04932 Non-alcoholic fatty liver disease     493687 (IL6)    04931 Insulin resistance     493687 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     493687 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     493687 (IL6)    01523 Antifolate resistance     493687 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:fca04052]     493687 (IL6) Cytokines and growth factors [BR:fca04052]  Cytokines   Interleukins    493687 (IL6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IL6 GCSF IL11 DUF4924 IL23 Sec16 Motif Other DBs NCBI-GeneID:  493687 NCBI-ProteinID:  NP_001009211 EnsemblRapid:  ENSFCTG00005010729 LinkDB All DBs Position A2:115008819..115014044 Genome browser AA seq 208 aa AA seqDB search MTFLSTSAFSPLAFSLGLLLVVATAFPTPGPLGGDATSNRLPLTSADKMEELIKYILGKI SALKKEMCDNYNKCEDSKEALAENNLNLPKLAEKDGCFQSGFNQETCLTRITTGLQEFQI YLKFLQDKYEGDKENAKSVYTSTNVLLQMLKRKGKNQDEVTIPVPTVEVGLQAKLQSQEE WLRHTTIHLTLRRLEDFLQFSLRAVRIM NT seq 627 nt NT seq  +upstreamnt  +downstreamnt atgaccttcctctccacaagcgccttcagtccactcgccttctccctggggctgctcctg gtggtggctactgctttccctaccccgggacccctgggaggagatgccacctcaaataga ctaccactcacctctgcagacaaaatggaagaactcattaagtacatcctcggcaaaatc tctgcactgaaaaaggagatgtgtgacaactataacaaatgtgaggacagcaaggaggca ctggcagaaaacaacctgaatcttccgaaactggcagaaaaagatggatgcttccaatct gggttcaatcaggagacctgcctgacaagaatcactactggtcttcaggagtttcagata tacctgaaattcctccaggacaagtatgagggtgataaggaaaatgccaagtctgtgtac accagtactaacgtcctgctccagatgctgaagcgtaagggaaagaatcaggatgaggta accatccctgtcccaaccgtagaagttggcctgcaggctaagctgcagtcacaggaagag tggctgaggcatacaacaattcacctcacccttcgaaggctggaggacttccttcagttc agcctcagggctgttcggataatgtaa

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