Felis catus (domestic cat): 493755 Help Entry 493755            CDS       T02385                                  Symbol TNF Name (RefSeq) tumor necrosis factor precursor   KO K03156   tumor necrosis factor superfamily, member 2 Organism fca  Felis catus (domestic cat) Pathway fca01523   Antifolate resistance fca04010   MAPK signaling pathway fca04060   Cytokine-cytokine receptor interaction fca04061   Viral protein interaction with cytokine and cytokine receptor fca04064   NF-kappa B signaling pathway fca04071   Sphingolipid signaling pathway fca04150   mTOR signaling pathway fca04210   Apoptosis fca04217   Necroptosis fca04350   TGF-beta signaling pathway fca04380   Osteoclast differentiation fca04612   Antigen processing and presentation fca04620   Toll-like receptor signaling pathway fca04621   NOD-like receptor signaling pathway fca04622   RIG-I-like receptor signaling pathway fca04625   C-type lectin receptor signaling pathway fca04640   Hematopoietic cell lineage fca04650   Natural killer cell mediated cytotoxicity fca04657   IL-17 signaling pathway fca04660   T cell receptor signaling pathway fca04664   Fc epsilon RI signaling pathway fca04668   TNF signaling pathway fca04920   Adipocytokine signaling pathway fca04930   Type II diabetes mellitus fca04931   Insulin resistance fca04932   Non-alcoholic fatty liver disease fca04933   AGE-RAGE signaling pathway in diabetic complications fca04936   Alcoholic liver disease fca04940   Type I diabetes mellitus fca05010   Alzheimer disease fca05014   Amyotrophic lateral sclerosis fca05020   Prion disease fca05022   Pathways of neurodegeneration - multiple diseases fca05132   Salmonella infection fca05133   Pertussis fca05134   Legionellosis fca05135   Yersinia infection fca05140   Leishmaniasis fca05142   Chagas disease fca05143   African trypanosomiasis fca05144   Malaria fca05145   Toxoplasmosis fca05146   Amoebiasis fca05152   Tuberculosis fca05160   Hepatitis C fca05161   Hepatitis B fca05163   Human cytomegalovirus infection fca05164   Influenza A fca05165   Human papillomavirus infection fca05166   Human T-cell leukemia virus 1 infection fca05168   Herpes simplex virus 1 infection fca05169   Epstein-Barr virus infection fca05170   Human immunodeficiency virus 1 infection fca05171   Coronavirus disease - COVID-19 fca05205   Proteoglycans in cancer fca05310   Asthma fca05321   Inflammatory bowel disease fca05322   Systemic lupus erythematosus fca05323   Rheumatoid arthritis fca05330   Allograft rejection fca05332   Graft-versus-host disease fca05410   Hypertrophic cardiomyopathy fca05414   Dilated cardiomyopathy fca05417   Lipid and atherosclerosis fca05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:fca00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     493755 (TNF)    04350 TGF-beta signaling pathway     493755 (TNF)    04064 NF-kappa B signaling pathway     493755 (TNF)    04668 TNF signaling pathway     493755 (TNF)    04071 Sphingolipid signaling pathway     493755 (TNF)    04150 mTOR signaling pathway     493755 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     493755 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     493755 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     493755 (TNF)    04217 Necroptosis     493755 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     493755 (TNF)    04620 Toll-like receptor signaling pathway     493755 (TNF)    04621 NOD-like receptor signaling pathway     493755 (TNF)    04622 RIG-I-like receptor signaling pathway     493755 (TNF)    04625 C-type lectin receptor signaling pathway     493755 (TNF)    04650 Natural killer cell mediated cytotoxicity     493755 (TNF)    04612 Antigen processing and presentation     493755 (TNF)    04660 T cell receptor signaling pathway     493755 (TNF)    04657 IL-17 signaling pathway     493755 (TNF)    04664 Fc epsilon RI signaling pathway     493755 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     493755 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     493755 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     493755 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     493755 (TNF)    05170 Human immunodeficiency virus 1 infection     493755 (TNF)    05161 Hepatitis B     493755 (TNF)    05160 Hepatitis C     493755 (TNF)    05171 Coronavirus disease - COVID-19     493755 (TNF)    05164 Influenza A     493755 (TNF)    05168 Herpes simplex virus 1 infection     493755 (TNF)    05163 Human cytomegalovirus infection     493755 (TNF)    05169 Epstein-Barr virus infection     493755 (TNF)    05165 Human papillomavirus infection     493755 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     493755 (TNF)    05135 Yersinia infection     493755 (TNF)    05133 Pertussis     493755 (TNF)    05134 Legionellosis     493755 (TNF)    05152 Tuberculosis     493755 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     493755 (TNF)    05144 Malaria     493755 (TNF)    05145 Toxoplasmosis     493755 (TNF)    05140 Leishmaniasis     493755 (TNF)    05142 Chagas disease     493755 (TNF)    05143 African trypanosomiasis     493755 (TNF)   09163 Immune disease    05310 Asthma     493755 (TNF)    05322 Systemic lupus erythematosus     493755 (TNF)    05323 Rheumatoid arthritis     493755 (TNF)    05321 Inflammatory bowel disease     493755 (TNF)    05330 Allograft rejection     493755 (TNF)    05332 Graft-versus-host disease     493755 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     493755 (TNF)    05014 Amyotrophic lateral sclerosis     493755 (TNF)    05020 Prion disease     493755 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     493755 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     493755 (TNF)    05418 Fluid shear stress and atherosclerosis     493755 (TNF)    05410 Hypertrophic cardiomyopathy     493755 (TNF)    05414 Dilated cardiomyopathy     493755 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     493755 (TNF)    04940 Type I diabetes mellitus     493755 (TNF)    04936 Alcoholic liver disease     493755 (TNF)    04932 Non-alcoholic fatty liver disease     493755 (TNF)    04931 Insulin resistance     493755 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     493755 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     493755 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:fca04052]     493755 (TNF)    00536 Glycosaminoglycan binding proteins [BR:fca00536]     493755 (TNF) Cytokines and neuropeptides [BR:fca04052]  Cytokines   Tumor necrosis fators    493755 (TNF) Glycosaminoglycan binding proteins [BR:fca00536]  Heparan sulfate / Heparin   Cytokines    493755 (TNF) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  493755 NCBI-ProteinID:  NP_001009835 UniProt:  P19101 LinkDB All DBs Position B2:30418662..30420419 Genome browser AA seq 233 aa AA seqDB search MSTESMIRDVELAEEALPKKAGGPQGSGRCLCLSLFSFLLVAGATTLFCLLHFGVIGPQR EELPHGLQLINPLPQTLRSSSRTPSDKPVAHVVANPEAEGQLQRLSRRANALLANGVELT DNQLKVPSDGLYLIYSQVLFTGQGCPSTHVLLTHAISRFAVSYQTKVNLLSAIKSPCQRE TPEGAEAKPWYEPIYLGGVFQLEKGDRLSTEINLPAYLDFAESGQVYFGIIAL NT seq 702 nt NT seq  +upstreamnt  +downstreamnt atgagcactgaaagcatgatccgggacgtggagctggccgaggaggcactccccaagaag gcagggggcccccagggctccggaaggtgcttgtgcctcagcctcttctccttcctcctc gtcgcaggagccaccacactcttctgcctgctgcactttggagtgatcggcccccagagg gaagagctcccacatggcctgcaactaatcaaccctctgccccagacactcagatcatct tctcgaactccgagtgacaagccagtagcccatgtagtagcaaaccccgaagctgaaggg caactccagcggctgagccggcgtgccaatgccctcctggccaatggcgtggagctgaca gacaaccaactgaaggtgccctcagacgggctgtacctcatctactcccaggtcctcttc acgggccaaggatgtccttccacacatgtgctcctcacccacgccatcagccgctttgcc gtttcctaccagaccaaggtcaacctcctctctgccatcaagagcccttgccagagggag accccagagggggctgaggccaagccctggtatgagcccatctacctgggaggggtcttc caactggagaagggtgatcgactcagcactgagatcaatctgcctgcctatcttgacttt gccgagtctgggcaagtctactttgggatcattgccctgtga

DBGET integrated database retrieval system