KEGG   Felis catus (domestic cat): 493760
Entry
493760            CDS       T02385                                 
Symbol
VWF
Name
(RefSeq) von Willebrand factor precursor
  KO
K03900  von Willebrand factor
Organism
fca  Felis catus (domestic cat)
Pathway
fca04151  PI3K-Akt signaling pathway
fca04510  Focal adhesion
fca04512  ECM-receptor interaction
fca04610  Complement and coagulation cascades
fca04611  Platelet activation
fca04613  Neutrophil extracellular trap formation
fca05165  Human papillomavirus infection
fca05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    493760 (VWF)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    493760 (VWF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    493760 (VWF)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    493760 (VWF)
   04611 Platelet activation
    493760 (VWF)
   04613 Neutrophil extracellular trap formation
    493760 (VWF)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    493760 (VWF)
   05165 Human papillomavirus infection
    493760 (VWF)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:fca03110]
    493760 (VWF)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:fca04147]
    493760 (VWF)
Chaperones and folding catalysts [BR:fca03110]
 Intramolecular chaperones
  Others
   493760 (VWF)
Exosome [BR:fca04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   493760 (VWF)
SSDB
Motif
Pfam: VWD VWA C8 VWA_N2 TIL VWC Pacifastin_I MCR_beta_N
Other DBs
NCBI-GeneID: 493760
NCBI-ProteinID: NP_001233208
UniProt: A0A061DD19
LinkDB
Position
B4:complement(41211845..41349251)
AA seq 2813 aa
MFPARPARVLLALALTLPGILCAKETVGRSSMARCSLFGGDFINTFDESMYSFMGDCSYL
LAGDCQKHSFSLIGDFQNGKRVSLSVYLGEFFDIHLFVNGTVLQGNQNISMPYASNGLYL
ETEAGYYKLSSETHGFVARIDGSGNFQILLSDRYFNKTCGLCGNFNIFAEDDFRTQEGTL
TSDPYDFANSWALSSGEQQCKRASPPSSPCNISSEEMQKGLWEQCQLLKSASVFARCHPL
VDPEPFVALCEKILCTCAQGLRCPCVALLEYARACAQQGMVLYGWTDHTACRPACPAGME
YKECVSPCARTCQSLHVKEVCQEQCVDGCSCPEGQLLDEGRCMESAECSCVHAGKRYPPG
ASLSQDCNTCICRNSLWVCSNEECPGECLVTGQSHFKSFDNRYFTFSGVCQYLLAQDCQD
HTFSVVIETVQCADDPDAVCTRSVTVRLPRLHNSLVKLKHGGGVSMDGQDVQIPLLQGDL
RIQHTVMASVRLSYGEDLQMDWDGRGRLLVMLSPIYAGKTCGLCGNYNGNRGDDFVTPAG
LAEPLVEDFGNAWKLHGDCEDLQKQHSDPCSLNPRLTRFAEQSCALLTSSKFEACHRVVN
PLPYVQNCRYDVCSCSDGKDCLCSAVANYAAACARRGVHIGWREPSFCALNCPQGQVYLQ
CGTPCNMTCRSLSYPDEDCNEICLEGCFCPAGLYLDERGHCVPKAQCPCYYDGEIFQPED
IFSDHHTTCYCEDGFMHCTTSGAPGSLLPDTFLSSPLSHRSKRSLSCRPPMVKLVCPADN
PRAEGLECAKTCQNYDLQCMSTGCVSGCLCPPGMVRHENRCVALERCPCFHQGREYAPGE
TVKIDCNTCVCRDRKWNCTDHVCDATCSAIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS
NPGTFRILVANEGCSYPSVKCKKRITILVGGGEIELFDGEVNVMKPMMDETHFEVVESGH
YVILLLGKALSVIWDHRLSISVALKQTYQEKVCGLCGNFDGIQNNDFTTSSLQVEEDPVD
FGNSWKVSPRCADTRKVPLDSSPATCHSNVMKQTMVDSSCRILTSDIFQDCNRLVDPDPF
LDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVAWRTATLCPQSCEERNLHENGY
ECEWRYNSCAPACPITCQHPEPLACPVQCVEGCHAHCPPGKILDELLQTCIDPKDCPVCE
VAGRRLASGKKITLNPDDPEHCQICHCDGVNLTCEACREPGGLVVPPTEGPVRATTPYVE
DTPEPPLHDFYCSRLLDLVFLLDGSSKLSEAEFEVLKAFVVGMMERLHISQKRIRVAVVE
YHDGSHAYIQLKDRKRPSELRRIASQVKYAGSEVASTSEVLKYTLFQIFGKIDRPEASRI
ALLLMASQEPQRLARNLIRYVQGLKKKKVIMIPVGIGPHANLKQIHTIEKQAPENKAFVL
SGVDELEQQRDKIINYLCDLAPEAPAPTQHPPMVPVTVGPGLMGVSSSGPKRNPTVLDVV
FVLEGSDKIGEANFNKSREFMEEVIRRMDVGQDGIHITVLQYSYMVTVEYTFREAQSKGE
VLQQVREIRYRGGNRTNTGLALQYLSEHSFSASQGDREQAPNLVYMVTGNPASDEIRRMP
GDIQVVPIGVGPHANLWELEQLGWPNAPILIQDFGVLPREAPDLVLQRCCSGDGLQIPTL
SPTPDCSQPLDVILLLDGSSNLPASYFDEMKSFAKAFISKANIGPQLTQVSVLQYGSITT
IDVPWNVAYEKVHLLSLVDLMQQEGGPSRIGDALGFAVRYVTSEVHGARPGASKVVVILV
TDVSMDLVDAAADAARSNRVTVIPIGIGDRYDEAQLRILAGPKASSNVVKLQRIEDLPTM
VTLGNSFFHKLCSGFLGVCVDEEGNEKRPGDIWTLPDQCHTVTCLPGGQTLLKSHRVNCD
RGPRPSCPNSQPPLRVEETCGCRWTCPCVCMGSSTRHIVTFDGQNFKLTGSCSYVLFQNK
EQDLEVILHNGACIPEXRQACTKSIEVKHDGLSVELHSDMQLTVNGRLVSVPYVGGDIEV
NVYGTIMYEMRFNHLGHIFTFTPQNNEFQLQLSPKTFASKMYGLCGICDENGANDFMLRD
GTVTTDWKVLIQEWTVQQPGKTCQPVPEEQCPVSSSSHCQLLLSALFAECHQLLAPATFY
AMCQQDSCHQEQVCEAIALYAHLCRTKGVCVDWRRSNFCAMSCPPSLMYNHCERGCPRLC
EGNTSSCGDHPSEGCFCPSHQVLLEGSCVPEEACTQCVSEDGVRHQFLETWVPSHQPCQI
CMCLSGRKVNCTTQPCPTARAPTCGPCEVARLRQSAEQCCPEYECVCDLSSCDVPLVPPC
EGGLQMTLTNPGECRPNFTCACRKDECRRESPPSCPPHRTPTLRKTQCCDEYECACSCVN
STVSCPLGYLASTVTNDCGCTTTTCFPDKVCVHRGTIYPVGQFWEEGCDVCTCTDMEDAV
MGLRVAQCSQKPCEDNCRSGFTYVLHEDECCGRCLPTACEVVTGSLRGDSQSHWRNVGSH
WASPDNPCLINECVRVKEEVFVQQRNVSCPQLDIPTCPVGFQLSCKASECCPTCHCEPLE
ACMLNGTIIGPGKSLMIDVCTTCHCTIQVGPVSGFKLECRKTTCEACPLGYKEQKNQGEC
CGRCLPVACTIQLRGGQTVMLKRDETLQDGCDSHICKVNERGEYIWEKRVTGCPPFDEHK
CLAEGGKIMKIPGTCCDTCEETECKDITARLQYVKVGNCKSEEEVDIHYCEGKCASKALY
SIDMEDVQDQCSCCSPTRTEPMRVPLRCTNGSLVYHEVLNAMQCTCSPRKCSK
NT seq 8442 nt   +upstreamnt  +downstreamnt
atgtttcctgccagacctgcgagagtgctgcttgctctggccctcaccttgccagggatc
ctttgtgcaaaagagactgttggcagatcgtcgatggctcgatgcagcctctttggaggt
gacttcatcaacacctttgatgaaagcatgtacagctttatgggagactgcagttacctc
ctggccggggactgtcagaaacactccttctcgcttattggggacttccaaaatggcaag
agagtaagcctctctgtgtatcttggggaattttttgacatccatttgtttgtcaatggt
actgtgctgcaggggaaccaaaacatctccatgccctacgcctccaacgggctgtatcta
gagactgaggctgggtactacaagctgtccagtgagacccacggctttgtggccagaatt
gatggcagtggcaattttcaaatcctgctgtcagacagatacttcaacaagacctgtggg
ctctgtggcaactttaacatctttgctgaggatgatttcaggactcaagaagggaccttg
acctcggacccctacgactttgccaactcctgggccctgagcagtggggaacaacagtgc
aaacgagcatcccctcccagcagcccgtgcaacatctcatctgaggaaatgcagaagggc
ctgtgggagcagtgtcagcttctgaagagtgcctcggtgtttgcccgctgccaccccctg
gtggaccccgagccttttgtggccctgtgtgaaaagattctgtgcacgtgtgcccagggg
ctgcggtgcccatgcgtggccctcttggagtatgcccgggcctgtgcccagcaggggatg
gtcttgtacggctggaccgaccacactgcatgccgaccggcatgtcctgctggcatggag
tataaggaatgcgtgtccccttgcgccagaacttgccagagcctgcacgtcaaagaagtg
tgtcaggagcaatgcgtggacggctgcagctgccctgagggacagctcctggatgaaggc
cgctgcatggaaagtgctgagtgttcgtgtgtgcacgccgggaagcggtaccctccagga
gcctccctctcgcaggactgcaacacctgcatttgccgaaatagcctgtgggtctgcagc
aatgaagaatgcccaggggagtgtctcgtcacaggacaatcccacttcaagagctttgac
aacaggtacttcaccttcagtggagtctgccagtatctgctggcgcaggactgccaggac
cacaccttctctgttgtcatagagactgtccagtgcgctgatgaccctgatgctgtctgc
acccgctctgtcactgtccgcctgcccagactgcacaacagccttgtgaagctgaagcat
gggggaggagtctccatggatggccaggacgtccagatccctctcctgcaaggtgacctc
cgcatccagcacaccgtgatggcgtccgtgcgcctcagctatggggaggacctacagatg
gactgggatggccgtgggaggctgctggtgatgctgtcccccatctatgccgggaagacg
tgcggcctgtgtgggaattacaatggcaacaggggtgacgacttcgtcacgcctgctggc
ctggccgagcccctggtggaggacttcgggaacgcctggaagctgcacggggactgtgag
gacctgcagaagcagcacagtgatccgtgcagcctcaacccgcgcctgaccaggtttgcg
gagcagtcgtgcgctctgttgacgtcctccaagttcgaggcctgccaccgcgtcgtgaac
cctctgccctacgtgcagaactgccgctatgacgtctgctcctgctccgacggcaaagac
tgtctctgcagcgccgtggccaactacgccgcagcctgtgcccggagaggcgtgcacatc
gggtggcgggagcccagcttctgtgcgctgaactgcccacagggccaggtgtacctgcag
tgtgggaccccttgcaacatgacctgtcgctccctttcttacccggatgaggactgcaat
gagatctgcctggaaggctgcttctgccccgcagggctgtacctggatgagaggggacac
tgtgtgcccaaggcccagtgcccctgttactatgatggcgagatcttccagcccgaggac
atcttctcagaccatcacaccacgtgctactgtgaggatggcttcatgcactgtaccaca
agtggagccccaggaagcctgctgcctgacactttcctcagcagccccctgtctcaccgc
agcaaaaggagcctgtcctgtcggccccccatggtcaagttggtgtgccctgctgacaac
ccgagggctgaagggctcgagtgtgccaagacctgccagaactacgacctgcaatgcatg
agcacgggctgcgtgtccggctgcctctgtcccccgggcatggtccggcatgaaaacaga
tgtgtggccctggaaaggtgtccctgcttccaccaaggcagagaatacgccccaggagaa
acggtgaaaattgactgcaacacttgtgtctgtcgggaccggaagtggaactgcacggac
catgtgtgtgacgccacgtgctctgccatcggcatggcgcactacctcaccttcgacggg
ctcaaatatctgttccctggagagtgccagtatgttctggtgcaggattactgtggcagt
aaccctggtaccttccggatcctggtggcgaatgaggggtgcagctacccatcagtgaaa
tgcaagaagcggatcaccatcctggtgggaggaggcgagattgaactgtttgatggggag
gtgaatgtgatgaagcccatgatggatgagacccactttgaggtggtggagtctggtcac
tatgtcattctgctgctgggcaaggccctctctgtgatctgggaccaccgcctgagcatc
tccgtggctctgaagcagacataccaggagaaagtgtgtggtctatgtgggaattttgat
ggcatccagaacaatgacttcaccaccagcagcctccaagtggaagaagatcccgtggac
tttgggaattcctggaaagtgagcccgcggtgtgccgacaccaggaaagtaccactggac
tcatcccctgctacctgtcacagcaacgtcatgaagcagacaatggtggattcctcctgc
aggatcctcaccagtgatattttccaggactgcaacaggctggtggaccctgacccattc
ctggatgtttgcatctacgacacttgctcctgtgagtccattggggactgtgcctgcttc
tgtgacaccattgctgcctacgcccacgtgtgtgcccagcacggcaaggtggtggcctgg
aggacagccacattgtgtccccagagctgcgaggagaggaatctccacgagaacgggtat
gagtgtgaatggcgctataacagctgtgccccggcctgtcccatcacgtgccagcatcct
gagccactggcgtgcccggtgcagtgtgtggaaggctgccatgcacactgccctccgggg
aaaatcctggatgagcttttgcagacctgcatcgaccccaaagactgtcctgtgtgtgag
gtggctggtcgtcgcttggcctcagggaagaaaatcaccttgaaccccgatgaccctgag
cactgccaaatttgtcattgtgatggtgtcaacctcacctgtgaggcctgcagggagcct
ggaggcctagtggtgccccccacagaaggcccggtcagagccaccaccccatacgtggag
gacaccccagagccgcccctccacgacttctattgcagcaggcttctggacctggttttc
ctgctagacggctcctccaagctgtccgaggctgagttcgaagtgctgaaggcctttgtg
gtgggcatgatggagcgtctgcacatctctcagaagcggatccgtgtggccgtggtggag
taccatgacggctcccacgcctacatccagctcaaggaccggaagcggccctcagagcta
cggcgcattgccagccaggtgaagtatgcaggcagtgaggtggcctccaccagcgaggtc
ttgaagtacactctgttccagatctttggcaagattgatcgccctgaagcatcccgcatt
gccctgctcctgatggccagccaggagccccagaggctggcccggaatttgatccgttac
gtgcagggcctgaagaagaagaaagtcatcatgatcccggtgggcatcgggccccatgcc
aacctcaagcagatccacaccattgagaagcaggcccccgagaacaaggcctttgtgctc
agtggtgtggacgagctggagcagcaaagggataaaattatcaactacctctgtgacctt
gcccccgaagcgcctgcccctacccagcatccccctatggtaccagtcactgtgggtcca
gggctcatgggggtttcatcctcgggacccaaaaggaaccccacagttctggacgtggtg
tttgtcctggaagggtccgacaaaattggtgaggccaactttaacaagagcagggagttc
atggaggaggtgattcggcgcatggatgtgggccaggacggcatccacatcacagtgctg
cagtactcgtacatggtgactgtggagtacaccttcagggaggcccagtccaagggtgag
gtcctgcagcaggtgcgggagatccggtaccggggtggcaataggaccaacactggactg
gccctgcagtacctgtctgaacacagcttctcagccagccagggggaccgggagcaggca
cctaacctggtctacatggtcactggaaaccccgcctccgatgagatcaggcggatgcct
ggagacatccaggtggtacccatcggagtgggccctcatgccaacctgtgggagctggag
cagctcggctggcccaacgcccccatcctcatccaggactttggcgtgctcccccgagag
gctcctgatctggtgctgcagaggtgctgctctggagacgggctgcagatccctaccctc
tcccccaccccagactgcagccagcccctggatgtgatcctcctcctggatggctcctcc
aacttgccagcttcttattttgatgaaatgaagagttttgctaaggctttcatttcaaaa
gccaacatagggcctcagctcactcaggtgtcagtgctgcagtatggaagcatcaccacc
atcgacgtgccgtggaatgtggcctatgagaaagtccatttgctgagcctcgtggacctc
atgcagcaggagggaggccccagccgaattggggatgctttgggctttgctgtgcgatat
gtcacctcagaagtccacggtgccaggcctggagcctcgaaggtggtggtcatcctggtc
acggatgtctccatggatttggtggacgctgcagccgatgcagccaggtccaaccgagtg
acagtgatccccattggaattggggatcggtatgatgaggcccagctgaggatcttggca
ggcccaaaggccagctccaatgtggtgaagctccagcgaatcgaagaccttcccaccatg
gtcaccctaggaaattccttcttccacaagctatgctctgggttccttggcgtttgcgtg
gatgaggaagggaatgagaagagacccggggacatctggaccctgccagaccagtgtcac
acagttacttgcctgccaggtggccagaccttgctgaagagtcatcgagtcaactgtgac
cgaggccccaggccatcatgtcccaacagccagccccctctcagggtggaggagacttgt
ggctgccgctggacctgcccctgtgtgtgcatgggcagctctacccggcacattgtgacc
tttgatggacagaatttcaagctgactggcagctgttcctatgtcctctttcaaaacaag
gagcaggacctggaggtgattctccataatggtgcctgcatccctgagaygaggcaggcc
tgcacgaagtccattgaggtgaaacatgacggcctctcagttgagctccacagtgacatg
cagctgacagtgaatggaagactggtctctgtcccatatgtgggtggggacatagaagtc
aatgtctatggcaccatcatgtatgagatgagattcaaccatcttggccacatcttcaca
ttcactccacaaaacaatgagttccagctgcagctcagccccaagacctttgcttcgaag
atgtatggtctctgtgggatctgcgatgagaacggggccaatgacttcatgctgagggat
ggcacggtcaccacagactggaaggtgctcatccaggaatggacggtacagcagccaggg
aagacgtgccagcctgttcccgaggaacagtgtcctgtctccagcagttcccactgccag
ctcctcctctcagccctgtttgccgaatgccaccagcttctggcaccagccaccttttac
gccatgtgccagcaggacagttgccaccaggagcaagtgtgtgaggcgattgccctgtac
gcccacctctgtcggaccaaaggagtctgtgttgactggaggaggagtaatttctgtgct
atgtcatgcccaccatccctgatgtataaccactgtgagcgtggctgcccccggctctgt
gaggggaatacgagctcctgtggggaccatccctcagaaggctgcttctgcccctcacat
caagtcctgctggaaggtagctgtgtccccgaggaggcctgtacccagtgtgtcagtgag
gatggagtccggcaccagttcctggaaacctgggtcccatcccaccagccctgccagatc
tgcatgtgcctcagtgggcggaaggtcaactgtacgacacagccctgccccaccgccaga
gctcccacatgcggcccctgtgaagtggcccgcctccgccagagtgcagagcagtgctgc
ccggagtatgagtgtgtgtgtgacctgtcgagctgtgatgtgccattggtgcctccctgt
gaaggtggcctccagatgaccctgaccaatcccggcgagtgcagacccaacttcacatgt
gcctgcaggaaggacgagtgcagaagggagtccccgccctcttgccccccacaccggacg
ccgacccttcggaagacccagtgctgtgatgagtatgagtgtgcttgcagctgcgtcaat
tccacggtgagctgcccactggggtacctggcctccactgtcaccaacgactgtggctgc
accacgacaacctgcttccctgacaaggtgtgtgtccaccgaggcaccatctaccctgtg
ggccagttctgggaggagggctgtgacgtgtgcacctgcaccgacatggaagatgctgtg
atgggtctgcgcgtggcccagtgctcccagaagccctgtgaggacaactgtcggtcgggc
ttcacttatgtcctccatgaagacgagtgctgtggaaggtgtttgccaactgcctgtgaa
gtggtgactggttcactgcggggggactcccagtctcactggaggaatgttggctctcac
tgggcctcccctgacaacccctgcctcatcaatgagtgtgtccgagtgaaggaagaggtc
tttgtgcaacagagaaatgtctcctgcccccagctggacatccctacctgccctgtgggc
ttccagctgagttgtaaggcgtcagagtgttgccccacctgtcactgcgagccactggag
gcctgcatgctcaatggcaccatcattgggcctgggaaaagtctgatgattgacgtgtgc
acgacctgccactgcaccatccaggtggggcccgtctctggattcaagctggagtgcagg
aagaccacctgtgaggcctgccccctgggttacaaggaacagaagaaccaaggtgaatgc
tgtggcagatgtctgcctgtggcttgcaccatccagctaagaggaggccagaccgtgatg
ttgaagcgtgatgagacactccaggatggctgtgatagtcacatctgcaaggtcaatgag
agaggagagtacatttgggagaagagggtcacaggctgcccgccctttgatgaacacaag
tgtctggccgagggagggaaaatcatgaaaattccaggcacctgctgtgacacatgtgag
gagacagaatgcaaggatatcactgccaggctgcagtatgtcaaagtgggaaactgtaag
tctgaagaggaagtggacattcattactgcgagggtaaatgtgccagcaaagccttgtac
tccatcgacatggaggatgtgcaggaccagtgctcctgctgctcgcccactcggacggag
cccatgcgggtgcccctgcgctgcaccaatggctccctcgtctaccatgaagtcctcaac
gccatgcagtgcacgtgctcccccaggaagtgcagcaagtga

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