KEGG   Felis catus (domestic cat): 493797
Entry
493797            CDS       T02385                                 
Symbol
TLR2
Name
(RefSeq) toll-like receptor 2
  KO
K10159  toll-like receptor 2
Organism
fca  Felis catus (domestic cat)
Pathway
fca04145  Phagosome
fca04151  PI3K-Akt signaling pathway
fca04613  Neutrophil extracellular trap formation
fca04620  Toll-like receptor signaling pathway
fca05132  Salmonella infection
fca05134  Legionellosis
fca05140  Leishmaniasis
fca05142  Chagas disease
fca05144  Malaria
fca05145  Toxoplasmosis
fca05146  Amoebiasis
fca05152  Tuberculosis
fca05161  Hepatitis B
fca05162  Measles
fca05168  Herpes simplex virus 1 infection
fca05169  Epstein-Barr virus infection
fca05170  Human immunodeficiency virus 1 infection
fca05171  Coronavirus disease - COVID-19
fca05205  Proteoglycans in cancer
fca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
fca05321  Inflammatory bowel disease
fca05323  Rheumatoid arthritis
fca05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    493797 (TLR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    493797 (TLR2)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    493797 (TLR2)
   04620 Toll-like receptor signaling pathway
    493797 (TLR2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    493797 (TLR2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    493797 (TLR2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    493797 (TLR2)
   05161 Hepatitis B
    493797 (TLR2)
   05171 Coronavirus disease - COVID-19
    493797 (TLR2)
   05162 Measles
    493797 (TLR2)
   05168 Herpes simplex virus 1 infection
    493797 (TLR2)
   05169 Epstein-Barr virus infection
    493797 (TLR2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    493797 (TLR2)
   05134 Legionellosis
    493797 (TLR2)
   05152 Tuberculosis
    493797 (TLR2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    493797 (TLR2)
   05144 Malaria
    493797 (TLR2)
   05145 Toxoplasmosis
    493797 (TLR2)
   05140 Leishmaniasis
    493797 (TLR2)
   05142 Chagas disease
    493797 (TLR2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    493797 (TLR2)
   05321 Inflammatory bowel disease
    493797 (TLR2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    493797 (TLR2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:fca04131]
    493797 (TLR2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:fca04147]
    493797 (TLR2)
   04054 Pattern recognition receptors [BR:fca04054]
    493797 (TLR2)
   04090 CD molecules [BR:fca04090]
    493797 (TLR2)
   00536 Glycosaminoglycan binding proteins [BR:fca00536]
    493797 (TLR2)
Membrane trafficking [BR:fca04131]
 Endocytosis
  Phagocytosis
   Toll-like receptors
    493797 (TLR2)
Exosome [BR:fca04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   493797 (TLR2)
Pattern recognition receptors [BR:fca04054]
 Membrane-bound pattern recognition receptors
  Toll-like receptors
   493797 (TLR2)
CD molecules [BR:fca04090]
 Proteins
  493797 (TLR2)
Glycosaminoglycan binding proteins [BR:fca00536]
 Hyaluronan
  Cell surface receptors
   493797 (TLR2)
SSDB
Motif
Pfam: LRR_8 LRR_4 TIR TIR_2 LRR_1 LRR_5 LRR_9 LRRCT LRR_6
Other DBs
NCBI-GeneID: 493797
NCBI-ProteinID: XP_003984979
UniProt: M3X0I5
LinkDB
Position
B1:complement(73801560..73813298)
AA seq 784 aa
MSRVLWTVWVLGAVTSLSKEVAPHQTSLSCDSTGVCEGHSRSLNSIPSGLTAAVRSLDLS
NNEITYIGNSDLQGCVNLRALRLESNEINTIEEDSFFSLGSLEHLDLSYNHISNLSSSWF
RPLSSLKFLNLLGNPYKSLGQTPLFSQLTTLRILKVGNIYSFTAIQEKDFAGLTFLEELE
IDASNLQKYEPESLKSIQNISHLALRMKQPDLLLEIFVDLLSSVEHLELRDTHLNTLHFS
KASINETNTSIKKWTFRNMKITDGSFSELVKLLNYVSGVLEVEFEDCTLHGLGDFDVSDM
GKIGSVGGIETLTVRRLVIPYFYSFRDLSSVYSLTERVKRVTVESSKVFLVPCLLSQHLK
SLEYLDLSDNLMVEEYLRNAACEHAWPLLQTLILRQNRLKSLEKTGETLLTLKNLINLDI
SKNSYLSMPETCQWPEKLKYLNLSNTRIYSLTRCIPWTLEILDISNNNLDSFSLTLPQLK
ELYISRNKLKTLPDASFLPTLQVMRISRNAINTFSKEQLDSFQRLTTLEAGGNNFICSCE
FLSFTREQQALAQILTDWPDNYLCDSPFYVRGQRVQDTHLPASECHRAALVSVVCCVLFL
LILLTGVLCHRFHGLWYLKMMWAWLQAKRKPRKAPQRDLCYDAFVSYSERDSHWVENLMV
QELEHFEPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTIFVLSENFVKSEWCKYELDFS
HFRLFDENNDAVILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPTDEAQQEGFWLNLRT
AIKS
NT seq 2355 nt   +upstreamnt  +downstreamnt
atgtcacgtgttttgtggacagtatgggtcttgggggctgtaaccagcctctccaaggaa
gtggcccctcatcagacttctctgtcctgtgactccacgggcgtctgcgagggccactcc
agatctttaaactccatcccttcaggactcacggcggctgtgagaagccttgacctctcc
aacaatgagatcacctacattggcaacagtgacctgcagggctgtgtgaacctcagggct
ctgaggctggagtctaatgaaattaacacgatagaggaagattcttttttttccctgggg
agtctcgaacatttggacttatcctataatcacatatctaatttatcatcctcgtggttc
aggcccctttcttccttaaagttcttaaacttgctgggaaatccttacaaatcacttggg
caaacacctcttttttctcagctcacaactttgcgaattctgaaagtgggaaatatttac
agtttcactgcgattcaggaaaaggattttgctgggctgacttttcttgaggaacttgag
attgatgcttcaaatctccagaagtatgagccagagagtttgaagtccattcagaacatc
agccatctggcccttcgtatgaaacagcctgatttgctgctggagatttttgtagatctt
ttaagttctgtggaacatttggaactgagagatactcatttgaacactttacatttttca
aaagcatccatcaatgaaacaaatacgtcgattaaaaagtggacgtttagaaacatgaaa
atcactgatggaagttttagcgaacttgtaaaactgttgaattacgtttctggagtgtta
gaagtagagtttgaggactgtactctccatgggcttggcgactttgacgtatctgacatg
ggcaaaattggaagtgtaggtgggatagagacattaacagtacggaggttggtcattcca
tacttctactcgtttcgtgatctgagtagtgtgtattcacttacagaaagagttaaaaga
gtcacagtagaaagcagtaaggtgtttctggttccttgtttactttcacaacatttaaaa
tcattagaatatttggatctcagtgacaatttaatggttgaagaatacttgagaaatgcc
gcctgtgagcatgcctggcccctcctacaaaccttaattttaaggcaaaatcgtttgaaa
tcattagaaaaaaccggagaaactttgcttactctgaaaaacttgattaaccttgatatt
agtaagaacagttatctttctatgcctgaaacttgtcagtggccagaaaagttgaaatat
ttgaacttatccaacaccagaatatacagcttaacccgatgcatcccctggacactggaa
attttagatattagcaataacaatctcgattcattttctctgactttgccacaactcaaa
gaactttatatttccagaaataagttgaagactctaccagatgcctccttcttacccacg
ttacaggtcatgagaatcagcagaaatgcaataaacactttctctaaggagcaacttgat
tcttttcaaagactgacgactttggaagctggcggcaacaatttcatttgctcctgtgaa
ttcctgtctttcacgcgggagcagcaagcactggcccagatcctgaccgactggccagac
aattacctgtgtgactctccattctacgtgcggggccagcgggttcaggacacccatctc
ccagcttctgaatgccacagggcagctctggtgtctgtcgtgtgctgtgtccttttcctg
ttgatcctgctcacgggggttctgtgccaccgtttccacgggctgtggtacctgaaaatg
atgtgggcttggctccaggccaaaaggaagcccaggaaagctccccagcgggacctctgt
tatgacgcctttgtgtcttacagcgagcgggattcccactgggtggagaaccttatggtc
caggagctggagcacttcgagcctcccttcaagttgtgtcttcacaagcgggacttcatt
cccggcaaatggattatcgacaacatcatcgactccatcgagaagagccacaaaaccatc
tttgtgctttctgaaaactttgtgaagagcgagtggtgcaagtacgagctggacttctcc
cacttccgtctgtttgatgagaacaacgatgctgtcattctcattcttctggagcccatt
gagaaaaaggccatcccccagcgtttctgtaagctgcggaagataatgaacaccaagacc
tacctggagtggcccacagacgaagctcagcaggaagggttttggttaaacttgagaact
gcaataaagtcctag

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