Felis catus (domestic cat): 554227
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Entry
554227 CDS
T02385
Symbol
CYP2E1
Name
(RefSeq) cytochrome P450 family 2 subfamily E member 1
KO
K07415
cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00140
Steroid hormone biosynthesis
fca00590
Arachidonic acid metabolism
fca00591
Linoleic acid metabolism
fca00980
Metabolism of xenobiotics by cytochrome P450
fca00982
Drug metabolism - cytochrome P450
fca00983
Drug metabolism - other enzymes
fca01100
Metabolic pathways
fca04932
Non-alcoholic fatty liver disease
fca04936
Alcoholic liver disease
fca05204
Chemical carcinogenesis - DNA adducts
fca05208
Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
554227 (CYP2E1)
00590 Arachidonic acid metabolism
554227 (CYP2E1)
00591 Linoleic acid metabolism
554227 (CYP2E1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
554227 (CYP2E1)
00982 Drug metabolism - cytochrome P450
554227 (CYP2E1)
00983 Drug metabolism - other enzymes
554227 (CYP2E1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
554227 (CYP2E1)
05208 Chemical carcinogenesis - reactive oxygen species
554227 (CYP2E1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
554227 (CYP2E1)
04932 Non-alcoholic fatty liver disease
554227 (CYP2E1)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
fca00199
]
554227 (CYP2E1)
Cytochrome P450 [BR:
fca00199
]
Cytochrome P450, animal type
CYP2 family
554227 (CYP2E1)
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Gene cluster
GFIT
Motif
Pfam:
p450
DUF6361
Motif
Other DBs
NCBI-GeneID:
554227
NCBI-ProteinID:
NP_001041475
UniProt:
Q5KR51
LinkDB
All DBs
Position
D2:87807781..87818837
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AA seq
495 aa
AA seq
DB search
MAALGITVALLVWMATLMLISVWKQIYSSWKLPPGPFPLPIIGNLLQLDFKNVPKSLTKL
AERYGPVFTLYLGSQRTVVLHGYKAVKEVLLDYKNDFSGRGEIYAFEAHKEKGITFNNGP
SWKDTRRLSLSILRDYGMGKLANEERIQREVPFLMEAFRKTQGQPFDPTFVLGYAPCNVI
SDILFRKRFDYTDQTGLRIQKLFNENFHLLSTSWLQLYNIFPSYMRYLPGNHRKVIKNVY
EIKSYTAARVKEHEESLDPNCPRDFTDSLLLEMRKERYTKEPWFTFDNIAATIADLFFAG
TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRLEMPYMDAVVHEIQRF
IDLLPSNLPHEAIQDTMFRGYVIPKGTVVVPTLDSLLFDNQEFPDPEKFKPEHFLNESGK
FKYSDYFKAFSAGKRVCVGEGLARMELFLFLSAILQHFNLKPLVDPKDIDLSPSTIGFAK
IPPRYKLCVIPRSGV
NT seq
1488 nt
NT seq
+upstream
nt +downstream
nt
atggctgccctgggcatcacagttgccctgttggtgtggatggccaccctcatgcttatc
tctgtctggaagcagatctacagcagctggaaactaccccctggccctttcccactgccc
attattgggaatcttctccagttggatttcaagaatgttcccaaatctttaaccaagttg
gcagagcggtatgggcctgtgttcaccttgtacctgggctcccagcgcaccgtagttctg
catggctataaggcggtgaaggaagtcctgctcgactacaagaatgacttttctggcaga
ggagaaatctatgcatttgaggcacacaaggaaaaaggaattacgttcaacaatgggccg
agctggaaggacacccggcgcctgtctctgagcatcctccgggactatggcatggggaag
cttgccaatgaggagcggatccagagggaggtgcccttcctgatggaggcattccggaag
acccaggggcagcccttcgaccccacctttgttctgggctatgctccctgcaacgtcatc
tcggacatcctcttccgcaagcgctttgactacacggaccaaaccgggctgaggatacag
aagctgttcaacgagaacttccacctgctcagcaccagctggctccaattatataacatt
ttcccaagctatatgcgctacctgcctggaaaccatagaaaagtaataaaaaatgtgtat
gaaataaaaagttatactgcagcaagagtgaaggagcacgaggagtcgctggaccccaac
tgcccccgggacttcaccgacagcctgctcctggagatgcggaaggaaagatacaccaaa
gagccttggttcacctttgacaacattgctgccaccatagctgacctgttttttgcgggt
acagagaccaccagcaccactctgagatatgggctcctgattctcatgaaatacccagag
atcgaagagaaactgcatgaagaaatcgacagggtgattgggccaagccgaatccctgcc
atcaaggaccggttagagatgccctatatggatgccgtggtgcatgagattcagcgattc
atcgacctcttgccctccaacctgccccatgaagcaatccaggacacaatgttcagagga
tacgtcatccccaagggtacggtcgtggtcccgacgctggactccctcttgtttgacaac
caagagttccctgatccggagaagtttaagccagagcactttctgaatgaaagtggaaag
ttcaagtatagtgactatttcaaggcattttctgcaggaaagcgggtgtgtgttggagaa
ggcctggctcgcatggagttgttcctgttcttgtccgccattttgcagcactttaacctg
aagcctctcgttgaccccaaggatatcgatctcagtcccagcacaattgggtttgccaaa
atcccaccccgttacaagctctgtgtcattccccgttcgggtgtgtga
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