KEGG   Fervidobacterium islandicum: NA23_00130
Entry
NA23_00130        CDS       T04215                                 
Name
(GenBank) dihydrofolate reductase family protein
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
fia  Fervidobacterium islandicum
Pathway
fia00670  One carbon pool by folate
fia00790  Folate biosynthesis
fia01100  Metabolic pathways
fia01240  Biosynthesis of cofactors
fia04981  Folate transport and metabolism
Module
fia_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:fia00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    NA23_00130
   00670 One carbon pool by folate
    NA23_00130
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    NA23_00130
Enzymes [BR:fia01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     NA23_00130
SSDB
Motif
Pfam: DHFR_1 RibD_C
Other DBs
NCBI-ProteinID: AMW31909
UniProt: A0AAI8CI05
LinkDB
Position
31166..31723
AA seq 185 aa
MKGKVVDTRIRLLAVTDVRGTIAINENDRTDWGSPEDKRLFKEITTRSGLVVMGRKTYEA
IGKRLPGRYNVVLSTKGVFSCGEPDLVLNGNVSQIIQELRNRGFEDVCVIGGQTLFSQFL
NAGLVTDLHLTIEPIILPDGLNLFSNIDKHYSLRFEKAQILNSKGTIYVHYRIGELGNKI
QGLKI
NT seq 558 nt   +upstreamnt  +downstreamnt
atgaaagggaaggtggttgatacgagaatcagattgctggcagtgacagatgtaagggga
actatcgcaattaatgaaaacgatagaacggattggggaagtccggaggacaaaagactt
ttcaaagaaataaccacccgctcaggtcttgttgttatgggcagaaagacctacgaagcg
attggtaaaagattgcccggaaggtacaacgttgttctgagcacaaagggcgtgttttct
tgtggagagcctgatttggtactaaacgggaacgtttcgcagataattcaggaacttagg
aaccgaggttttgaagacgtgtgcgttatcggtggtcagactttgttttctcaatttcta
aacgctggtcttgtaacagacttacacttgacaatagaaccgataatcctacctgacggg
ttgaatcttttttcaaatattgacaaacactactcattacgctttgaaaaagctcagatt
ctgaattctaagggaactatctacgtgcattatcgaattggagagcttggaaacaaaata
cagggtttgaaaatctga

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