Ferrovum myxofaciens: HO273_04250
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Entry
HO273_04250 CDS
T06614
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
fmy
Ferrovum myxofaciens
Pathway
fmy00010
Glycolysis / Gluconeogenesis
fmy00020
Citrate cycle (TCA cycle)
fmy00620
Pyruvate metabolism
fmy00785
Lipoic acid metabolism
fmy01100
Metabolic pathways
fmy01110
Biosynthesis of secondary metabolites
fmy01120
Microbial metabolism in diverse environments
fmy01200
Carbon metabolism
fmy01210
2-Oxocarboxylic acid metabolism
Module
fmy_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
fmy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HO273_04250 (aceE)
00020 Citrate cycle (TCA cycle)
HO273_04250 (aceE)
00620 Pyruvate metabolism
HO273_04250 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HO273_04250 (aceE)
Enzymes [BR:
fmy01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HO273_04250 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
QKE39705
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Position
956100..958766
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AA seq
888 aa
AA seq
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MASPPKDHDSDPQETQEWLDALNGVLCTEGPERAHFLLERLVDKARRSGAFLPYSANTAY
LNTIPPALEEPMPGNPEMEYRIRSLIRWNALAMVVRANKGGEELGGHIASFQSAATLYDV
GFDYFFRAPTPEHGGDVLYTQGHSAPGIYARAFLEGRLSEEQLAHFRREVEGKGLSSYPH
PWLMPDFWQMPTVSMGLGPLMSIYQARFMKYLQNRGLAQTEGRKVWAFMGDGEMDEPESL
GAISLAARENLDNLIFVVNCNLQRLDGPVRGNGKIIQELEADFRGAGWNVIKVIWGSPWD
ALIAKDTSGLLLQRMMEAVDGEYQSFKAHDGAYVRQHFFGKYPELLRLVANMSDDEIWHL
SRGGHDAFKVYNAYLAAVRHSDQPTVILAKTIKGYGMGEAGEGQNITHQQKKMGESALKQ
FRNRFKIPIDDAVIAAAPFYRPADDSPEIRYLQERRQALGGYLPVRHSASAPLDIPPLEY
FAPLLEASGERHLSTTMAFVRLLNLLIRDETLSQRIVPIVPDESRTFGMEGMFRSLGIYS
SVGQLYEPQDHDQLMYYRESVNGQILQEGINEAGAFSSWIAAATSYSTHGVTTLPFYIFY
SMFGFQRVGDLAWAAGDMQCRGFLIGGTAGRTTLNGEGLQHQDGHSQVHASFIPNCISYD
PTYAYELAVIIQDGLHRMFHAQENVFYYLTTMNENYAHPALPEGAREGILKGMYLLHERA
ASRGPCVQLLGSGTILREVEAAAQLLATDWGVSSNVWSCPSFNELAREGQNVLRHNRHHP
TEPAQIPYVTQCLKDTRGPVIAATDYIKTFTEQIRAFVPRRFVTLGTDGFGRSDTRAQLR
HFFEVDRYYVVEAALHALADEGVIPLSQVAEAQRKYALDPAKPNPLKV
NT seq
2667 nt
NT seq
+upstream
nt +downstream
nt
atggcatcaccccccaaggatcacgattcagatccccaggaaacacaggaatggctggat
gcgctgaatggcgtgctctgtacggagggaccggaacgggcccatttcctgcttgaacga
ttggtggacaaggctcgtcgttcgggggccttcctgccctatagtgccaatacggcctac
ctcaataccattcctccagcgctcgaagaacccatgcccgggaacccggaaatggaatac
cgcatccgttccctgattcgctggaatgccttggccatggtggtacgggccaacaagggt
ggggaagaactgggtgggcatatcgccagttttcagtcggcggccactctgtatgatgtg
ggcttcgactacttttttcgtgcacctaccccggagcatgggggggatgtgctctacacc
caaggtcactcggccccgggcatttatgcccgcgcctttctggaaggacgcctgagcgaa
gaacaactggcccacttccgccgcgaagtggagggcaaggggttatccagttacccccat
ccctggctcatgcccgatttttggcaaatgcccaccgtctccatgggacttggtcccctc
atgtccatttatcaggcccgtttcatgaaatacctgcaaaaccgcgggttggcccagacc
gaaggacgcaaggtgtgggctttcatgggcgatggagagatggacgaacccgaatctctg
ggcgccatttccttggccgcccgagaaaatcttgacaacctgatcttcgtggtgaattgt
aacctgcaacgtctcgacggtcccgtgcgcggaaatggcaaaatcattcaggaactggaa
gcggattttcgcggggctggctggaacgtcatcaaagtgatctggggaagcccctgggat
gccctcattgccaaggacaccagtggcttgctgctgcagcgcatgatggaagccgtggat
ggggaataccaaagtttcaaggcacacgatggcgcctacgtgcgtcagcattttttcggc
aaatatcccgagttgctgcgcctggtggccaacatgtccgatgacgagatctggcatctg
tcgcgcggcggacacgacgccttcaaggtctataatgcctacctggcggcggtgcgtcac
agtgaccaacccacggtgattctggccaagaccatcaaaggctatggcatgggcgaagcg
ggcgaagggcaaaacatcacccaccaacaaaagaagatgggcgaaagcgccctcaagcag
ttccgtaaccgcttcaagatccccatcgacgatgccgtaatcgccgctgcccccttctac
cgccctgccgatgacagcccggagatccgttatctgcaggaacggcgccaggctctgggc
ggctatctgccggtgcggcacagtgccagtgcgcctctggacatcccccccctggaatat
tttgcacccttgctggaagccagtggcgaacgtcatctatccaccaccatggccttcgtg
cgtctccttaatctactcatccgcgatgagacactgagtcagcgcatcgtccccattgtt
cccgacgaatcccgtaccttcggcatggagggcatgttccgtagcctgggcatctattct
tccgtggggcaattgtacgaaccccaggatcatgatcaactgatgtactaccgcgaaagc
gtgaatggtcagatccttcaggaagggatcaatgaagccggcgctttctcttcctggatc
gccgccgccacgtcttattccacccatggcgtcaccactctcccgttctatattttttat
tccatgttcggttttcagcgcgtcggtgatctggcctgggcggcaggggacatgcagtgt
cgcggcttcctcatcggcgggacggcgggacggaccaccctgaatggcgaagggttgcag
caccaggacggacacagtcaggttcatgcctccttcattcccaactgtatctcctacgac
cctacctatgcctatgaactggcggtcatcattcaagacggcctgcatcgcatgttccac
gctcaggaaaacgtcttttactacctcaccaccatgaatgaaaactatgcccaccctgcg
cttcccgagggggcacgggaaggcattctcaaaggcatgtacctattgcatgaacgggcg
gcatccaggggcccttgcgtccagttgctgggatcgggcaccatcctgcgcgaagtggag
gcagctgcccaactgttggccacggactggggcgtgtcgagcaacgtgtggagttgcccc
agtttcaatgaattggccagagaaggtcaaaatgtcctgcgccacaaccgtcatcacccc
acagaaccggctcagattccctacgtcacccagtgtctgaaagacacccgtgggccggtg
attgcggccaccgactacatcaaaaccttcacggaacaaatccgtgccttcgtaccccgt
cgtttcgtaaccctgggtaccgatggatttggccgttccgacacgcgcgcccaattgcgc
cattttttcgaagtagatcgttactatgtggtggaagccgcactccatgccttggctgac
gagggcgtaatccccctgtcccaggtggccgaagcgcaacgaaaatatgctctcgacccc
gccaaaccgaatccgctgaaggtctga
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