Francisella philomiragia O#319-067: KU46_128
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Entry
KU46_128 CDS
T03619
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
fpx
Francisella philomiragia O#319-067
Pathway
fpx00010
Glycolysis / Gluconeogenesis
fpx00020
Citrate cycle (TCA cycle)
fpx00620
Pyruvate metabolism
fpx00785
Lipoic acid metabolism
fpx01100
Metabolic pathways
fpx01110
Biosynthesis of secondary metabolites
fpx01120
Microbial metabolism in diverse environments
fpx01200
Carbon metabolism
fpx01210
2-Oxocarboxylic acid metabolism
Module
fpx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
fpx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
KU46_128 (aceE)
00020 Citrate cycle (TCA cycle)
KU46_128 (aceE)
00620 Pyruvate metabolism
KU46_128 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KU46_128 (aceE)
Enzymes [BR:
fpx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
KU46_128 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AJI49719
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Position
complement(131441..134119)
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AA seq
892 aa
AA seq
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MSDFTKDIDVLETQEWLEAFEDVIKREGADRAKFLFEQLLSKGAELGIESAYSTAKIKRY
INSIDVSEQPSYPGDMEIEQRIEAINRWNSAVIVASANKREGSIGGHIGTGAGAMTLYEV
GFNHFWKAPNENHAGDLIFYQGHLSPIVYARSYLEGRITKQQLENFRRQAFDKENAVSSY
PHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRRVWAFCGDGEMDEPE
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSD
WDRLLQDQKGGKKLAQRLSELNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDEDI
QALRRGGHDPIKIYAAYKKAIEQANGKPTLILPMTVKGYGLGEWGESKNIAHNVKKLDTD
ALEHIKNRFNVPATKEDIENYKLVSLPEDSAEMKYLHAKRAALGGYIPARLENKEPLAIP
TYQEFAKNLLEDSGDREFSTTTAFVRILSHLAKDKKLGKHIVPITVDESRTFGMEGLFRQ
LGIYNPKGQQYVPEDKEQVMFYKEAKDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIP
FMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLNGEGLQHEDGHSHIQAGLIPN
CISYDPTYAYELAVILGEGMNRMYVKGEHVYYYITVMNENYSHRAMPAGCEEGIIKGLYK
LEDTKPADKHVQLLGSGSILREVEAAAKMLKDEYGITSNVWSMTSANELHREAKKVAREN
MLHPDAERKESYIEKCLKNEQGPVIASTDYIKLYTDQLREFIPHTYVNLGTDGFGRSDTR
EALRSFFEVDRYHVVVASLYALHLDGKVKASEVKDAIKKYNIDPERVAPLYC
NT seq
2679 nt
NT seq
+upstream
nt +downstream
nt
atgtcggatttcactaaagatattgatgttttagaaacccaagagtggcttgaggctttt
gaagatgtcattaaaagagaaggtgctgatagagctaagtttttatttgaacagttgctt
agtaagggtgctgaacttggtatagaaagtgcttactcaacagcaaaaataaaaagatat
ataaactctatagatgtttctgaacagccaagttatcctggtgatatggaaattgagcaa
agaatcgaagctataaatagatggaattcagcagtaatagtagcatcagctaacaaaaga
gaaggttctatcggtggtcatatcggtactggtgctggtgctatgactctatatgaggtt
ggttttaaccatttttggaaggctccaaatgaaaatcatgctggtgatttgattttctat
caaggacacctttctccaatcgtgtacgctcgttcgtatctggaaggtagaattactaag
cagcaattagagaactttagaagacaagcttttgacaaagaaaacgctgtatcttcatat
ccacatccatatttgcaacctacgtattggcagttcccaacggtatctatgggtctaggt
cctttgcaggcgatttatcaagctagatttatgaagtatcttgaggctagaggtctagct
aagacttctgatcgtcgtgtatgggcgttctgtggtgatggtgagatggatgagccagaa
tcaattggttctattactagagcagggcgtgaaggcttagataacctaatatttgtagtt
aactgtaacttacagagattagatggccttgtaaatggtaatggtaatattgtcgaagaa
ctagcagatgtatttgctggtgctggctggaatgttatcaaggtactatggagtagtgat
tgggatagattactacaagatcaaaaaggcggcaaaaagcttgctcaaagattaagtgaa
ctaaatgatggtcaattccatacaatcaaagctcatggtggtgcagagtgtcgtagagtg
gtatttagtggcgatgaagatcttgaagcattagctaaagatatgacagatgaagatatt
caagcgttacgacgtggtggtcatgatcctatcaagatttatgctgcatataagaaagct
attgagcaagcaaatggtaagccaacacttatcctacctatgactgttaaaggttatggt
ttaggtgagtggggtgaatctaaaaatattgcacacaacgtcaaaaaacttgatacagat
gctcttgagcatatcaaaaatagatttaatgttcctgctacaaaagaagatatcgaaaat
tataaattagtttctttacctgaagattctgctgagatgaagtatcttcatgcgaaaaga
gcagctttaggtggttatattccagcaagattggagaataaagagccattagctattcca
acttatcaagagtttgcaaaaaacttattagaagatagtggtgatagagagttctctact
actacagcttttgtaagaatactatctcacttagcaaaagataagaaattaggtaaacat
atcgtaccaatcacagttgatgaatcacgtacttttggtatggaaggtctattcagacag
ttgggtatttataaccctaaaggtcagcagtatgtacctgaagataaagagcaagtaatg
ttctacaaagaagctaaagatggtcagatcctacaagagggtatcaacgagcaaggtgga
ttctgttcatggatagcagcagctacttcatacagcgttcataaagtgccaatgattcct
ttcatgatttactactctatgttcggtttccaaagatttggagatcttgcatgggcagct
ggtgattctatggcaaaaggttttgtcattggtggtacttctggtcgtacaactctaaat
ggtgaaggtctacagcacgaagatggtcatagccatatccaagctggtctaattcctaac
tgtatttcttatgatcctacttatgcttatgagttagctgtaattcttggcgaaggtatg
aatagaatgtatgttaaaggtgagcatgtatattactatatcactgtaatgaatgagaat
tattctcacagagctatgccagctggttgtgaagaaggtattatcaaagggttgtataag
ttagaagataccaagccagctgataagcatgtgcagttattaggttcaggttctatacta
agagaagttgaggctgctgctaagatgctaaaagatgagtatggtattacttcaaatgtt
tggagtatgacttctgctaatgagcttcatagagaagctaaaaaagtagcaagagaaaat
atgctacatccagatgctgagagaaaagaaagctacatagaaaaatgcttgaagaatgag
caaggccctgtgattgcttctactgattacatcaagctatatacggatcagctaagagaa
tttataccacatacttatgttaacttaggtactgatgggtttggtagatctgatactcgt
gaagctctaagaagtttctttgaggttgatagatatcacgtagttgtagcatcattatat
gctttacatttagatggtaaagtcaaggctagcgaagttaaagatgcgattaagaaatat
aatatagacccagagcgtgtagctccgctatattgctaa
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