Francisella sp. LA112445: FIP56_08520
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Entry
FIP56_08520 CDS
T08878
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
frl
Francisella sp. LA112445
Pathway
frl00010
Glycolysis / Gluconeogenesis
frl00020
Citrate cycle (TCA cycle)
frl00620
Pyruvate metabolism
frl00785
Lipoic acid metabolism
frl01100
Metabolic pathways
frl01110
Biosynthesis of secondary metabolites
frl01120
Microbial metabolism in diverse environments
frl01200
Carbon metabolism
frl01210
2-Oxocarboxylic acid metabolism
Module
frl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
frl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
FIP56_08520 (aceE)
00020 Citrate cycle (TCA cycle)
FIP56_08520 (aceE)
00620 Pyruvate metabolism
FIP56_08520 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FIP56_08520 (aceE)
Enzymes [BR:
frl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
FIP56_08520 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QIW10739
UniProt:
A0A7M3TDD4
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Position
complement(1765355..1768033)
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AA seq
892 aa
AA seq
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MSDFTKDIDALETQEWLEAFEDVVKREGVDRAKFLFEQLLTKGSELGIQSAYSTAKVKSY
INSIDVSEQPSYPGDMELEERIEAVNRWNSAVMVAAANKKDGSIGGHIGTGAGAMTLYEV
GFNHFWKAPNDNHAGDLIFYQGHLSPIVYARSFLEGRITEKQLENFRRQAFDGENAVSSY
PHPHLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAETADRKVWAFCGDGEMDEPE
SMGAITRAGREGLDNLIFVINCNLQRLDGLVNGNGNIVEELANSFMGAGWDVIKVLWSSD
WDKLLQDPKGGKKLAQRLSELNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMSDADI
ASLRRGGHDPLKIYAAYKKATETKNGRPILILPMTVKGYGLGEWGESKNIAHNVKKLDTD
ALEHIKNRFNVPATKDDVESYRLIKLPEDSPEMKYLHSKRKDLGGYIPKRLENNQALEVP
SYKEFAKSLLDDSGDREFSTTTAFVRILSHLAKDKKIGKHIVPITVDESRTFGMEGLFRQ
LGIYNPQGQQYVPEDKKQVMFYKESKDGQILQEGINEQGGLSSWLAAATSYSVHKVPMIP
FMIYYSMFGFQRFGDLAWAAGDSMAKGFLLGGTSGRTTINGEGLQHEDGHSHIQAGLIPS
CISYDPTYAYELAVIMGEGLKRMYVDGEHVFYYITVMNENYSHRAMPEGVEEGILKGLYK
LEDNKPADKHVQLMGSGTILREVEAASKMLKEEYGITSNVWSMTSANELYRDAKNVARTN
MLHPTDKKKESYIEQCFKNEQGPVVASTDYIKLYTDQLREFIPSTFVSLGTDGYGRSDSR
AALRSFFEVDRYHVVVASLYALHLDGKVEASEVKAAIEKYNIDPERVAPFYS
NT seq
2679 nt
NT seq
+upstream
nt +downstream
nt
atgtcggatttcactaaagatattgatgctttggagactcaagaatggcttgaggctttt
gaagatgtcgttaaaagagaaggcgttgatagagctaagtttttatttgaacagctttta
actaaaggttcagagttaggcatacaaagtgcttattctacagctaaggttaagagttac
attaactctatcgatgttagtgagcaacctagctatccaggagatatggagctagaagag
cgaattgaggccgtaaatagatggaactctgctgttatggttgcagcagctaataaaaaa
gatggctcaataggtggtcatattggtactggtgctggtgctatgactctttatgaggtt
ggttttaaccatttctggaaagctccaaatgataatcatgcaggtgatttgatattctat
caaggacatctttctccaatcgtgtatgcgcgttcattcttagaaggtagaataacagag
aaacagttagaaaactttagaagacaagcttttgatggtgagaatgcagtatcttcgtat
ccgcatccacatctacaacctacatattggcagttcccaacagtttctatgggtctaggc
cctcttcaagctatttatcaagctagatttatgaagtatttagaagctagaggattagct
gaaactgcagatcgtaaagtttgggctttctgtggtgatggtgagatggatgaaccagaa
tcaatgggtgctatcactagagctggtagagaaggtttagataatcttattttcgttatt
aactgtaacctacaaagattagatggtcttgtaaatggtaatggtaacattgttgaagag
cttgctaattcatttatgggtgcaggatgggatgttattaaagtcctctggagtagtgat
tgggataaattattacaagacccaaaaggcggtaagaaattagcacaaagattaagtgag
cttaatgatggacaattccatacaattaaagctcatggtggtgctgaatgtcgtagagtt
gtatttagtggagatgaagatctagaagctttagcgaaagatatgtctgatgctgatatt
gcttctcttcgtcgcggaggtcatgatccattaaagatctatgctgcgtataagaaagct
actgaaactaaaaatggtcgtccaatacttatattgccaatgactgttaaaggttatggt
ctaggtgagtggggcgagtcaaaaaatattgctcataatgttaagaagctagatacagat
gcacttgagcatattaaaaatagatttaatgttccagcaacaaaagatgatgttgagagc
tatagacttatcaagttacctgaagattctccagagatgaaatatcttcattctaagaga
aaagatttaggtggttatattcctaagagattagaaaataatcaagctttagaagttcct
agttacaaagaatttgctaaaagcctattagatgatagtggtgatagagagttttctaca
acaactgctttcgttagaatattgtctcatttagcaaaagacaaaaagattggaaaacat
attgtaccaataacagttgatgagtcacgtacttttggtatggaaggcttatttagacaa
ttaggtatatataatccacaaggtcaacagtatgtaccagaagataaaaagcaagttatg
ttctataaagaaagtaaagatggacaaattttgcaagaaggtattaacgagcagggtgga
ttaagctcttggttagccgcagctacttcttatagtgtgcacaaggtacctatgattcca
tttatgatctattactcaatgtttggtttccaaagatttggagatcttgcttgggctgct
ggagactctatggcaaaaggtttcttgcttggaggaacatctggtcgtacgacaattaat
ggtgaaggcttacagcacgaagatggacatagccatattcaagctggacttattcctagc
tgtatatcatatgaccctacatatgcttatgaattagcggtgatcatgggtgaaggtctt
aagagaatgtatgtggatggtgagcatgttttctactatattacagtaatgaatgaaaac
tattctcatagagcaatgcctgaaggtgttgaagaaggtattcttaaaggtttatataaa
ctagaagataacaaacctgctgataagcacgttcaattaatgggttctggtactatctta
agagaggttgaagcagcttctaaaatgctgaaagaagaatatggtataacttctaatgtt
tggagtatgacttctgcaaatgagctatatagagatgctaaaaatgtagctagaacaaac
atgcttcacccaacagataagaaaaaagaaagttatattgagcaatgctttaaaaatgag
caaggcccagttgttgcatctactgattatattaaattatatactgatcagcttagagag
tttatcccaagtacatttgtaagcttaggtactgatggatatggtagatctgatagtaga
gcagctttacgtagcttctttgaagtagatagatatcatgtggttgttgcatcattatat
gctttacatttagatggtaaagttgaggctagtgaagttaaagcggcaattgaaaagtac
aatatagacccagagcgtgtagctccattttatagctaa
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