KEGG   Candidatus Protofrankia datiscae: FsymDg_0989
Entry
FsymDg_0989       CDS       T01530                                 
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 subunit
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
fsy  Candidatus Protofrankia datiscae
Pathway
fsy00020  Citrate cycle (TCA cycle)
fsy00630  Glyoxylate and dicarboxylate metabolism
fsy00785  Lipoic acid metabolism
fsy01100  Metabolic pathways
fsy01110  Biosynthesis of secondary metabolites
fsy01120  Microbial metabolism in diverse environments
fsy01200  Carbon metabolism
fsy01210  2-Oxocarboxylic acid metabolism
Module
fsy_M00009  Citrate cycle (TCA cycle, Krebs cycle)
fsy_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:fsy00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    FsymDg_0989
   00630 Glyoxylate and dicarboxylate metabolism
    FsymDg_0989
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    FsymDg_0989
Enzymes [BR:fsy01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     FsymDg_0989
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     FsymDg_0989
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     FsymDg_0989
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     FsymDg_0989
SSDB
Motif
Pfam: E1_dh 2-oxoacid_dh Transket_pyr OxoGdeHyase_C 2-oxogl_dehyd_N
Other DBs
NCBI-ProteinID: AEH08494
UniProt: F8AXZ5
LinkDB
Position
complement(1151193..1154948)
AA seq 1251 aa
MAAPTVPESGPDFGPNEWLVFEIYQQYLADPESVSPQWREFLSDYRPEGVNGQPGVAGPV
PPAVADGAVPAAGGVPDAVPAGQPATAPTAATPVTPAAPVASAAPVASAPAATAVPAATA
VPTAGQSAPAADGGVPTSPLRGAAARVVANMETSLHVPTATSVRAVPAKLLADNRIVINR
HLARSRGGKVSFTHLIGYAMVRALQATPVMNHSYTEVGGKPALVTPEHVNLGIAIDLVKG
SSRQLVVVAIKQAETMDFSQFWLTYEDLIRRARTNKITADDFANVTITLTNPGGIGTVHS
VPRLMQGQGTIIGVGAMEYPAEFQGASQETLSRLAVSKIITLTSTYDHRIIQGAQSGEYL
RRIHQLLLGADDFYEEVFRSLRVPYEPVQWVADITSSHEGDLDHGTRVLELIHAYRVRGH
LMADTNPLEFAIRSHPDLDIISHGLTLWDLDREFPVDGFAGQRTMTLRDILGVLRDSYCR
RVGIEYMHIQEPDERVWIQQRVERSAERPDPAEQLHVLERLGAAEAFESFLQTKYVGQRR
FSLEGGESAIPLLDEVLQRASEAGMDEVAFGMAHRGRLNVLANIIGKSYRQIFAEFEGYV
DPQTAHGSGDVKYHLGAEGVYTTPDGREVAVSLVSNPSHLEAVDPVLEGVVRAKQDLLNK
GPEGFTVLPVLIHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHLVINNQVGFTTSPVSSR
SSVYATDVARMVQAPIFHVNGDDPEACVRVARLAVEFRQAFHKDVVIDMVCYRRRGHNEM
DEPSFTQPLMYDTIATKRSVRKLYTEALIGRGDITPAEAEQAMKDYSAQLEKAFAETRDT
TSRPASQPRLVTTPAEAAAAAAVSTAVSLDVVKKIIDTQTTLPEGFTVHPRLRPQLERRA
QMVATGAIDWACAETIAFGSILLDGRPIRLAGQDSRRGTFGQRHAVLVDRHTGEEYSPLK
SLEVESGAGTFYVHDSLLSEFAAMGFEYGYSVARPDALVLWEAQFGDFANGAQSIIDEFI
AAGEAKWGQRSAVGLLLPHGYEGQGPDHSSARVERFLSLCAENNMLVSAPSSPASYFHLL
RRQALSPVRRPLVVFTPKSMLRLKAATSTVEELTGGSWLPVIDDASVGDHAGIRRVLLSS
GKVYYDLLATRAKKEITGTALVRVEQLYPTPVAELRAVLATYPNLTEVTWVQEEPANQGA
YPHMAIHLPEALPAGLVLRRASRNASAAPASGSSSRHEKEQAELLGQAFAG
NT seq 3756 nt   +upstreamnt  +downstreamnt
gtggcagcaccgacggtacccgagtccggccccgacttcggccccaacgagtggctggta
ttcgagatctaccagcagtacctcgccgatccagagagcgtctcgccacagtggcgcgag
ttcctctccgactaccggccagagggtgtcaacggccagccaggcgtggcggggcccgtc
ccgccagccgtcgccgacggtgcggtaccggccgcgggcggtgtccccgacgcggtccca
gccggccagccggccaccgcgccgaccgccgcgaccccggtgacccccgcggctcccgtg
gccagcgcggctcccgtggccagcgcgccagcggcaacagccgtaccagcggcaacagcc
gtaccaacggccggccagagcgctcccgccgcggacggtggcgtcccgacgtcaccgttg
cgaggcgccgccgcccgcgtcgtcgcgaacatggagacgtccctgcatgtccccacggcg
acgtcggtgcgggcggtgcccgccaagctgctcgcggacaaccggatcgtcatcaaccgg
catctggctcgttcccgcggcggcaaggtgtccttcacgcacctgatcggctacgccatg
gtcagggcgctgcaggccaccccggtgatgaaccactcctacaccgaggtcggtggcaag
cccgccctggtcacgccggaacacgtcaacctgggcatcgccatcgacctggtcaagggc
tcctcgcgccagctggtcgtcgtcgcgatcaagcaggccgagacgatggacttcagccag
ttctggctcacctacgaggacctcatccggcgcgcccggacaaacaagatcacggcggac
gacttcgccaacgtgacgatcacgctgaccaaccccggcggcatcggcaccgtgcactcg
gtgccccgcctgatgcagggccaggggacgatcatcggggtcggcgcgatggagtacccg
gccgagttccagggcgcctcccaggagaccctgtcgagactggccgtctcaaagatcatc
actctgaccagcacctacgaccaccggatcatccagggtgcgcagtccggcgagtacctg
cgccgcatccaccagctgctgctgggcgcggacgacttctacgaggaggtcttccgctca
ttgcgcgtcccgtacgagccggtgcagtgggtcgccgacatcacctcgtcccacgagggc
gatctcgaccacggcacccgggtgctggaactgatccacgcctaccgggtccgcggccac
ctgatggccgacaccaacccgctcgagttcgccatccgcagccaccccgacctcgacatc
atcagccacgggctgaccctgtgggacctcgaccgcgagttccccgtcgacggcttcgcc
ggccagcggacgatgaccctgcgcgacattctgggcgtcctgcgggactcctactgccgc
cgggtcggcatcgagtacatgcacatccaggagccggacgagcgggtctggatccagcag
cgggtcgaacgctccgccgagcgtcccgacccagccgagcagctgcacgtcctcgagcgg
ctgggcgcggccgaggcgttcgagtccttcctgcagaccaagtacgtcgggcagcggcgc
ttctccctcgaaggcggggagtcggcaatcccgctgctggacgaggtcctgcaacgggcc
tccgaggccggcatggacgaggtcgccttcgggatggcccaccgtggccgtctcaacgtc
ctggcgaacatcatcggcaagtcctaccggcagatcttcgccgagttcgaggggtacgtc
gacccgcagaccgcgcacggctcgggtgacgtcaagtaccacctcggtgccgagggcgtc
tacaccactcccgacggccgcgaggtggcggtctccctggtgtccaacccctcccacctg
gaggcggtcgacccggtgctcgaaggcgtcgtccgtgccaaacaggacctgctcaacaag
ggtccggagggcttcaccgtcctgcccgtgctcatccacggggacgccgccttcgccggc
cagggcgtggtcgccgagacgctgaacctctcccagctgcgcggctaccgcaccggcggc
accgtgcatctcgtcatcaacaaccaggtcgggttcacgacctcgccggtgtccagccgg
tcgtcggtgtacgccaccgacgtcgcccggatggtgcaggccccgatcttccacgtcaac
ggggacgaccccgaggcgtgtgtgcgcgtcgcgcggctggccgtcgagttccggcaggcg
ttccacaaggacgtcgtgatcgacatggtgtgctaccggcggcgcggccacaacgagatg
gacgagccgtcgttcacccagccgctgatgtacgacaccatcgccaccaagcggtcggtg
cgcaagctctacacggaggccctgatcggccgtggcgacatcaccccggccgaggccgag
caggccatgaaggactactcggcgcagctggagaaggcgttcgcggaaacccgcgacacc
accagccggccggccagccagccccggctggtgacgaccccggcggaggccgccgccgcg
gccgccgtgtccaccgccgtgtcgctggacgtcgtcaagaagatcatcgacacccagacc
acgctgccggagggcttcaccgtccacccgaggctgcgcccgcagctcgagcgccgggcc
cagatggtcgccaccggggcgatcgactgggcgtgcgccgagaccatcgcgttcggttcg
atcctgttggacgggcggcccatccgcctcgccgggcaggacagccggcgcggcaccttc
ggccagcggcacgcggtcctggtcgaccggcacaccggcgaggagtactcgccgctgaag
tcgctggaggtcgagtcgggcgccggcaccttctacgtccacgactcgctgctgtccgag
ttcgccgcgatgggcttcgagtacggctactcggtggcccggccggacgcgctcgtgctg
tgggaggcccagttcggtgacttcgccaacggcgcccagtcgatcatcgacgagttcatc
gcggcgggcgaggccaagtgggggcagcgcagcgcggtcggcctgctgctcccgcacggc
tacgagggccaggggccggaccactcctcggcgcgcgtcgaacgcttcctcagcctgtgc
gccgagaacaacatgctggtgtcggccccgtccagcccggcgagctacttccacctgctg
cgccggcaggcgctctcgcccgtgcgccgcccgctggtcgtcttcacccccaagtcgatg
ctgcggctgaaggcggcgacgtcgacggtcgaggagctgaccggcgggtcgtggctgccg
gtcatcgacgacgcgagcgtcggtgaccacgccggcatccgccgggtgctgctgtccagc
gggaaggtctactacgatctgctggccacacgggccaagaaggagatcaccggcaccgcg
ctcgtccgggtcgaacagctctacccgaccccggtcgcggagctgcgcgcggtgctggcg
acctacccgaacctcaccgaggtgacctgggtgcaggaggaacccgccaaccagggtgcc
tacccgcacatggccatccatctgccggaggcgctgcccgccggcctggtgctgcgccgg
gcctcccgtaacgcgtcggccgcgccagcctccggctcctcctcgcggcacgagaaggag
caggcggagctgctcggacaggcgttcgccgggtag

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