Candidatus Protofrankia datiscae: FsymDg_2524
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Entry
FsymDg_2524 CDS
T01530
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
fsy
Candidatus Protofrankia datiscae
Pathway
fsy00010
Glycolysis / Gluconeogenesis
fsy00020
Citrate cycle (TCA cycle)
fsy00620
Pyruvate metabolism
fsy00785
Lipoic acid metabolism
fsy01100
Metabolic pathways
fsy01110
Biosynthesis of secondary metabolites
fsy01120
Microbial metabolism in diverse environments
fsy01200
Carbon metabolism
fsy01210
2-Oxocarboxylic acid metabolism
Module
fsy_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
fsy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
FsymDg_2524
00020 Citrate cycle (TCA cycle)
FsymDg_2524
00620 Pyruvate metabolism
FsymDg_2524
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FsymDg_2524
Enzymes [BR:
fsy01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
FsymDg_2524
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AEH09890
UniProt:
F8B294
LinkDB
All DBs
Position
2989321..2992110
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AA seq
929 aa
AA seq
DB search
MAKDSGRRFSVITDGLPSQLPDIDPSETGEWLESLDSVIDEQGRGRARFLMLKLLERARE
KAVGVPGLTSTDFINTIPPEQEPWFPGDEHIERRIRAYVRWNAAIMVSRANRPEYGVGGH
IATYASSAALYEVGFNHFFRGKDNLTGGPGGDSGDQVFIQGHASPGIYARAFLEGRLTAA
QLDAFRRESEPGGLSSYPHPRLMPDFWEFPTVSMGLGPIHAIYQARFNRYLLNRRIKDTS
GSRVWAFLGDGEMDEPESIGALGIAAREELDNLIFVVNCNLQRLDGPVRGNGKIMQELES
LFRGAGWNVIKVVWGRDWDPLLAKDTDGVLVHRMNTTPDGQFQTYTTSSGAYIREHFFGV
DARLRRMVKDLSDDELRKLSRGGHDYHKLYAAYKAATEHAGQPTVILAHTIKGWTLGKDF
EARNATHQMKKLSKADLKEFRDRLYLDIPDSELESGLPPYFHPGPDSEEIQYMGERRAAL
DGTLPRRVVRARPLPQPPESIFGDLRRGSGKQPVATTMAFVRLLKDLIKTKEMGARFVPV
IPDEARTFGMDAMFPTAKIYSPHGQRYEAVDRELLLSYQESESGQMLHEGINEAGSMGSV
IAAGTAYATHGVHMIPVYVFYSMFGFQRTGDQMWALGDQLGRGFLLGATAGRTTLNGEGL
QHQDGHSLLLASTNPACVAYDPAFAFEVAHIVRDGLDRMYGERGEDVFYYLTVYNESFPQ
PAEPAGVDPAQVLAGMYLFRPFAEAGLPVRPPADTGSPDAGSSAGGSSDAEPPRAQLLAS
GTGMRWALDAQELLANDFGVQADVWSVTSWNELRREALSCEEHNLLNPDSVERRPYVTRL
LQGAPGPVIAVSDWMRAVPDQISRWIPQDYSSLGTDGYGRSDTRAALRRHFHVDAESITV
ATLEALTRHGAIKATVVEDAIRRYRLREA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
gtggcgaaggacagcggcaggaggttctcggtcatcaccgacgggcttcccagccagttg
ccggacatcgacccgtccgaaaccggcgaatggctggagtccctggactcggtgatcgac
gagcagggccgtggccgggcccgattcctcatgctgaagctgctggaacgggcccgggag
aaggctgtcggagtgcccggactcaccagcaccgatttcatcaacaccatcccgccggag
caggaaccgtggttccccggggacgagcacatcgaacggcgcatccgggcctatgtccgc
tggaacgctgccatcatggtaagccgtgcgaaccggcccgaatacggcgtcggcggacat
atcgcgacatacgcgtccagcgccgctctctatgaggtgggattcaaccacttcttccgc
ggcaaggacaacctgaccggcgggcccggcggcgactcgggcgaccaggtgttcattcag
ggacacgcctcgccgggtatctacgcccgggcctttctcgagggccggctgaccgcggcg
cagctcgacgcgttccgccgggagagcgagcccggtgggctgtcctcctatccgcatccc
cgtctcatgcccgatttctgggagttcccgaccgtctcgatgggcctcgggccgatccac
gccatctaccaggcccggttcaaccgctatctgctgaaccggcggatcaaggacacttcc
ggcagccgggtgtgggccttcctcggtgacggcgaaatggacgagcccgagtcgatcggc
gcgctcggcatcgccgcgcgcgaggagctcgacaacctcatcttcgtcgtgaactgcaat
ctgcagcgcctcgacgggccggtccgcggcaacgggaaaatcatgcaggagctggagtcg
ctgttccgcggcgccggctggaacgtcatcaaggtggtctggggccgcgactgggacccg
ctgctggccaaggacaccgacggggtgctcgtccaccggatgaacaccaccccggacggc
cagttccagacctatacgacatcgtccggcgcgtacatccgggaacatttcttcggggtg
gacgcgcggctgcgccgtatggtcaaggacctgtccgacgacgagctgcgcaaactctcc
cgcggcgggcacgactaccacaagctgtacgcggcctacaaggcggcgaccgagcacgcg
ggccagcccaccgtcatcctcgcccacaccatcaagggctggacgctgggcaaggacttc
gaggcgcgtaacgccacgcaccagatgaagaaactctccaaggctgatctcaaggagttc
cgcgaccggctctatctggacattcccgactccgagctggagagcggcctgccgccctac
ttccatcccggcccggattcggaggagatccagtacatgggggaacggcgggccgctctg
gacggcacgctgccgcgacgggtcgtgcgcgcccggcctctcccgcagccgccggagtcc
atcttcggtgacctgcgccggggctcgggcaagcagccggtggccaccacgatggccttc
gtccggctgctcaaggacctgatcaagacgaaggagatgggcgcccggttcgtcccggtc
attccggacgaggcacgtaccttcggtatggacgccatgttcccgaccgccaagatctac
tcaccgcacggccaacgttacgaggccgtggaccgtgagctcctgctttcctaccaggag
tccgagtccggccagatgctgcacgagggaatcaacgaggccggttcgatgggatcggtc
atcgccgcgggcaccgcatatgccacccacggggtgcacatgattccggtgtacgtgttc
tactcgatgttcggattccagcggaccggcgaccagatgtgggcgctcggtgaccagctc
ggccgcggcttcctgctcggtgccaccgcgggccgcacgaccctcaacggcgaggggctt
cagcaccaggacggccactccctgctgctcgcctcgacgaacccggcgtgtgtggcctac
gacccggcgttcgccttcgaggtcgcccacatcgtccgggacggcctcgaccgcatgtac
ggcgaacgcggcgaggacgtcttctactacctgaccgtctacaacgagtcgttcccgcag
ccggccgagccggccggagtcgacccggcgcaggtactcgccggcatgtacctgttccgg
ccgttcgccgaggcgggcctgccggtacggccgccggccgacaccggctcccccgacgcc
ggctcctcggcgggcggctcgtcggacgccgagccgccccgtgcgcagctgctggccagc
ggcaccgggatgcgctgggcgctggacgcccaggagctgctcgcgaacgacttcggcgta
caggcggacgtgtggtcggtgacctcctggaacgagctgcgccgcgaggcgctcagctgc
gaggaacacaacctgctcaacccggactcggtggaacgccggccgtacgtgacccggctc
ctgcagggggcacccgggccggtgatcgccgtcagtgactggatgcgtgcggtaccggac
cagatctcccgctggattccccaggactactcctccctgggcaccgacgggtacggacgc
tcggacacccgggcggcgctgcgccgccacttccacgtcgacgccgagtcgatcacggtg
gcgaccctggaagctctgacccgccacggtgcgatcaaggcgacggtcgtcgaggacgcg
atccgccggtaccggctgcgggaggcgtga
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