| Entry |
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| Symbol |
aceE
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| Name |
(GenBank) pyruvate dehydrogenase (acetyl-transferring)
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| KO |
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| Organism |
fth Francisella tularensis subsp. holarctica OSU18
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| Pathway |
| fth01110 | Biosynthesis of secondary metabolites |
| fth01120 | Microbial metabolism in diverse environments |
| fth01210 | 2-Oxocarboxylic acid metabolism |
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| Module |
| fth_M00307 | Pyruvate oxidation, pyruvate => acetyl-CoA |
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| Brite |
KEGG Orthology (KO) [BR:fth00001]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
FTH_0310 (aceE)
00020 Citrate cycle (TCA cycle)
FTH_0310 (aceE)
00620 Pyruvate metabolism
FTH_0310 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FTH_0310 (aceE)
Enzymes [BR:fth01000]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
FTH_0310 (aceE)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
297139..299820
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| AA seq |
893 aa
MSDFTKDIDVLETQEWLEAFEDVIKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNY
VNSIDVSEQPSYPGDIELEQKIEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEV
GFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITAEQLENFRKQAFNGQNAVSSY
PHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPE
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSD
WDKLLQDPRGGKKLAQRLSELNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDI
QALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYGLGEWGESKNIAHNVKKLDTD
ALEHIKNRFNVPASKEDIENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALEIP
SYKDFAKSLLDDSGDREFSTTTAFVRILSYLAKDKNLGKHIVPITVDESRTFGMEGLFRQ
LGIYNPHGQQYVPEDKQQVMFYKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIP
FMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLNGEGLQHEDGHSHIQAGLIPN
CISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYFHRAMPEGCEEGIIKGLYK
LDEEKKPASKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVARA
NMLHPTAEKKESYIEKCFKNEQGPVIASTDYIKLYTDQLREFIPHTFVNLGTDGFGRSDT
RAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEKYNIDPERMAPFYS |
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| NT seq |
2682 nt +upstreamnt +downstreamnt
atgtcggatttcactaaagatattgatgttttagaaacccaagaatggcttgaggctttt
gaagatgtcataaaaagagaaggtgctgatagagccaagtttttatttgaacaattactt
gctaaaggttccgagcttggtataaaaagtgcttactcaactgctaaagttaagaactat
gtcaactctatagatgtctctgaacaaccaagttatccaggagatatagagcttgaacaa
aagattgaagctatcaatagatggaactctacagttatagtagctgcagctaataagaaa
gatggttctataggtggacatattggtactggtgccggcgctatgacgctttatgaagta
ggtttcaaccatttttggaaagcacccaatgatgaacatgctggtgatttgatattctat
caaggacatctttctcctattgtttatgcgcgttcattcctagaaggtagaataactgca
gaacagttagaaaactttagaaagcaagcatttaatgggcaaaatgcggtatcttcatat
cctcatccttatctacaaccgacttattggcagttcccaactgtttctatggggttagga
ccacttcaagctatttatcaagctagatttatgaagtatctagaggctaggggtttagca
aaaacatctgatcgcaaagtttgggcattctgtggtgatggcgagatggatgagccagaa
tcaattggttctatcactagagcaggtcgtgaagggctggataaccttatatttgtagtt
aattgtaatctacaaaggctagatggtctggtaaatggtaatggtaatattgttgaagaa
ttagcagatgtatttgctggtgctggttggaatgttatcaaggtgttgtggagtagtgac
tgggataaattattacaagatccaagaggtggtaaaaaacttgctcaaaggttaagtgaa
ttaaatgatggacaattccatacaattaaagctcatggtggtgctgagtgtcgtagagtt
gtctttagcggtgatgaagatttagaagcgctagctaaggatatgacagatgatgatatt
caagcattacgtcgtggaggccatgatccattgaaaatttatgcagcatataagaaggcg
gtagagaatccaaatggtcgtccaacactaattcttcctatgactgttaagggctatggt
ttaggggagtggggtgagtcaaaaaatattgcccacaatgtcaaaaaacttgatactgat
gcacttgagcacatcaaaaatagattcaatgtcccggcttcaaaagaggatatcgaaaac
tatagactcatcaagctagatgaaaattcgcctgagatgaaatatctacactctaagaga
aaagacctaggtggttatattcctaagagattggagaataagcaagcattagagattcca
agctataaagattttgctaagagcttattggatgatagtggtgatagagaattttcaact
actaccgcatttgtaagaatattatcctacttggcaaaagataagaatctagggaagcat
attgtaccaatcacggtagacgagtcacgtacttttggtatggagggcttgtttaggcag
ttaggtatctataacccacatggtcagcaatatgtgccagaagataaacagcaagtaatg
ttctataaagagtctgtagatggtcagattttacaagaaggtattaatgagcaaggaggt
ttttgttcttggattgccgcagctacttcatatagcgtacacaaggttccaatgattcct
ttcatgatttactactcaatgtttggtttccaaagatttggtgatcttgcttgggcagct
ggcgattcgatggcaaaaggttttgtaattggtgggacttcaggacgtacaactctaaat
ggcgaaggtttgcagcatgaagatggtcatagccatatccaagctggtcttatacctaat
tgtatctcttatgatcctacatatgcttatgaattagctgtaatccttggcgaaggtatg
aagagaatgtatgttgatggtgatcatgtatattactatattacagtaatgaatgagaac
tactttcatagagcgatgccagagggctgtgaagaaggtatcatcaagggcttatataag
ttagatgaagagaaaaagccagcatctaagcatgtacagctattgggttctggttctatt
ctaagagaagttgaagctgcagctaagatgctaaaagaagagtatggaattacttctaat
gtttggagtatgacttcagcaaatgagctttatagagaagctaaagatgtagctagagct
aatatgcttcacccaacagcagagaaaaaagaaagctatatcgagaagtgctttaaaaat
gagcaaggtcctgtaatcgcttctacggactatattaagctttatactgatcagttaaga
gaatttataccgcatacttttgtgaacttaggtacagacggctttggtagatctgatact
cgagcagcgctaagaagtttctttgaggttgatagatatcatgtcgttgttgcttcatta
tatgctctatatttagatggcaaagttgaggctagcgaagttaaagctgcgattgagaag
tacaatatagatccagagcgtatggcacctttttatagctaa |
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