Francisella tularensis subsp. holarctica LVS: FTL_0309
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Entry
FTL_0309 CDS
T00331
Name
(GenBank) pyruvate dehydrogenase, E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ftl
Francisella tularensis subsp. holarctica LVS
Pathway
ftl00010
Glycolysis / Gluconeogenesis
ftl00020
Citrate cycle (TCA cycle)
ftl00620
Pyruvate metabolism
ftl00785
Lipoic acid metabolism
ftl01100
Metabolic pathways
ftl01110
Biosynthesis of secondary metabolites
ftl01120
Microbial metabolism in diverse environments
ftl01200
Carbon metabolism
ftl01210
2-Oxocarboxylic acid metabolism
Module
ftl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ftl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
FTL_0309
00020 Citrate cycle (TCA cycle)
FTL_0309
00620 Pyruvate metabolism
FTL_0309
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FTL_0309
Enzymes [BR:
ftl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
FTL_0309
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
CAJ78750
UniProt:
A0AAI8BG66
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Position
295558..298239
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AA seq
893 aa
AA seq
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MSDFTKDIDVLETQEWLEAFEDVIKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNY
VNSIDVSEQPSYPGDIELEQKIEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEV
GFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITAEQLENFRKQAFNGQNAVSSY
PHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPE
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSD
WDKLLQDPRGGKKLAQRLSELNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDI
QALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYGLGEWGESKNIAHNVKKLDTD
ALEHIKNRFNVPASKEDIENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALEIP
SYKDFAKSLLDDSGDREFSTTTAFVRILSYLAKDKNLGKHIVPITVDESRTFGMEGLFRQ
LGIYNPHGQQYVPEDKQQVMFYKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIP
FMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLNGEGLQHEDGHSHIQAGLIPN
CISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYFHRAMPEGCEEGIIKGLYK
LDEEKKPASKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVARA
NMLHPTAEKKESYIEKCFKNEQGPVIASTDYIKLYTDQLREFIPHTFVNLGTDGFGRSDT
RAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEKYNIDPERMAPFYS
NT seq
2682 nt
NT seq
+upstream
nt +downstream
nt
atgtcggatttcactaaagatattgatgttttagaaacccaagaatggcttgaggctttt
gaagatgtcataaaaagagaaggtgctgatagagccaagtttttatttgaacaattactt
gctaaaggttccgagcttggtataaaaagtgcttactcaactgctaaagttaagaactat
gtcaactctatagatgtctctgaacaaccaagttatccaggagatatagagcttgaacaa
aagattgaagctatcaatagatggaactctacagttatagtagctgcagctaataagaaa
gatggttctataggtggacatattggtactggtgccggcgctatgacgctttatgaagta
ggtttcaaccatttttggaaagcacccaatgatgaacatgctggtgatttgatattctat
caaggacatctttctcctattgtttatgcgcgttcattcctagaaggtagaataactgca
gaacagttagaaaactttagaaagcaagcatttaatgggcaaaatgcggtatcttcatat
cctcatccttatctacaaccgacttattggcagttcccaactgtttctatggggttagga
ccacttcaagctatttatcaagctagatttatgaagtatctagaggctaggggtttagca
aaaacatctgatcgcaaagtttgggcattctgtggtgatggcgagatggatgagccagaa
tcaattggttctatcactagagcaggtcgtgaagggctggataaccttatatttgtagtt
aattgtaatctacaaaggctagatggtctggtaaatggtaatggtaatattgttgaagaa
ttagcagatgtatttgctggtgctggttggaatgttatcaaggtgttgtggagtagtgac
tgggataaattattacaagatccaagaggtggtaaaaaacttgctcaaaggttaagtgaa
ttaaatgatggacaattccatacaattaaagctcatggtggtgctgagtgtcgtagagtt
gtctttagcggtgatgaagatttagaagcgctagctaaggatatgacagatgatgatatt
caagcattacgtcgtggaggccatgatccattgaaaatttatgcagcatataagaaggcg
gtagagaatccaaatggtcgtccaacactaattcttcctatgactgttaagggctatggt
ttaggggagtggggtgagtcaaaaaatattgcccacaatgtcaaaaaacttgatactgat
gcacttgagcacatcaaaaatagattcaatgtcccggcttcaaaagaggatatcgaaaac
tatagactcatcaagctagatgaaaattcgcctgagatgaaatatctacactctaagaga
aaagacctaggtggttatattcctaagagattggagaataagcaagcattagagattcca
agctataaagattttgctaagagcttattggatgatagtggtgatagagaattttcaact
actaccgcatttgtaagaatattatcctacttggcaaaagataagaatctagggaagcat
attgtaccaatcacggtagacgagtcacgtacttttggtatggagggcttgtttaggcag
ttaggtatctataacccacatggtcagcaatatgtgccagaagataaacagcaagtaatg
ttctataaagagtctgtagatggtcagattttacaagaaggtattaatgagcaaggaggt
ttttgttcttggattgccgcagctacttcatatagcgtacacaaggttccaatgattcct
ttcatgatttactactcaatgtttggtttccaaagatttggtgatcttgcttgggcagct
ggcgattcgatggcaaaaggttttgtaattggtgggacttcaggacgtacaactctaaat
ggcgaaggtttgcagcatgaagatggtcatagccatatccaagctggtcttatacctaat
tgtatctcttatgatcctacatatgcttatgaattagctgtaatccttggcgaaggtatg
aagagaatgtatgttgatggtgatcatgtatattactatattacagtaatgaatgagaac
tactttcatagagcgatgccagagggctgtgaagaaggtatcatcaagggcttatataag
ttagatgaagagaaaaagccagcatctaagcatgtacagctattgggttctggttctatt
ctaagagaagttgaagctgcagctaagatgctaaaagaagagtatggaattacttctaat
gtttggagtatgacttcagcaaatgagctttatagagaagctaaagatgtagctagagct
aatatgcttcacccaacagcagagaaaaaagaaagctatatcgagaagtgctttaaaaat
gagcaaggtcctgtaatcgcttctacggactatattaagctttatactgatcagttaaga
gaatttataccgcatacttttgtgaacttaggtacagacggctttggtagatctgatact
cgagcagcgctaagaagtttctttgaggttgatagatatcatgtcgttgttgcttcatta
tatgctctatatttagatggcaaagttgaggctagcgaagttaaagctgcgattgagaag
tacaatatagatccagagcgtatggcacctttttatagctaa
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