KEGG   Francisella tularensis subsp. tularensis WY96-3418: FTW_0501
Entry
FTW_0501          CDS       T00495                                 
Symbol
ligA
Name
(GenBank) DNA ligase, NAD-dependent
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
ftw  Francisella tularensis subsp. tularensis WY96-3418
Pathway
ftw03030  DNA replication
ftw03410  Base excision repair
ftw03420  Nucleotide excision repair
ftw03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:ftw00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    FTW_0501 (ligA)
   03410 Base excision repair
    FTW_0501 (ligA)
   03420 Nucleotide excision repair
    FTW_0501 (ligA)
   03430 Mismatch repair
    FTW_0501 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ftw03032]
    FTW_0501 (ligA)
   03400 DNA repair and recombination proteins [BR:ftw03400]
    FTW_0501 (ligA)
Enzymes [BR:ftw01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     FTW_0501 (ligA)
DNA replication proteins [BR:ftw03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     FTW_0501 (ligA)
DNA repair and recombination proteins [BR:ftw03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     FTW_0501 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     FTW_0501 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     FTW_0501 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      FTW_0501 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 Nlig-Ia PTCB-BRCT DNA_ligase_ZBD HHH BRCT_2 RNA_ligase
Other DBs
NCBI-ProteinID: ABO46420
UniProt: A4IWW8
LinkDB
Position
491882..493918
AA seq 678 aa
MTPNEFFSIKYHILAKAELKAYIDKLADYLSQQSYLYHTLDKPIISDSDYDKLFRLLQDL
VNDNPQFKPINSVLDRVGGEVLAGFETIKHKKKMTSLANVFSLEELRDFYDKIEYDIELE
CEPKMDGLAISIFYKNGKFDYAVTRGDGIQGEKVSENVKTIRNVPLKLNTSNPPEELEVR
GEIILDKQSFLSLNEYMQTHENKTFANPRNAAAGSIRMLDSKVVAKRPLKLYSYGIGYFS
KDFVYPETQFELMQLLQSFGFTISDNMFLAKNFSEVEEYHHKMSHQRADLAYDIDGLVFK
VNNIKLQDTIGYTARGPKWAIAYKFPAEEVESEVLNVEFQVGRTGAITPVARLKPVAVGG
VIVSNATLHNINEIKRKDIRVGDRVIVRRAGDVIPEVVKSLPQYRKSDAQMVEMPTNCPV
CDSKIENVNDQAIYRCTGGWHCQAQTTERLKHFVSRKAMDIDKLGAKLIEQLVAANLIKY
PADIYKLNFEQLTGLERMAAKSSQNVLDSITKSKEPSLARFIFAIGIKDIGEVSSDALAN
HFGSLESFRDAKFEELIEINDIGEIMANNIVSFWHDSLNIKIVEEFLAIGIKIQNPVKVE
HAYNESFTGKTVVITGSFENYGRTELTQLLKSIGAKVTSSVSKKTDMVICGDNAGSKLTK
AQELGVEVILEDNLKDLL
NT seq 2037 nt   +upstreamnt  +downstreamnt
atgactccaaacgaatttttttctataaaatatcatattttagctaaagcagaattaaaa
gcttacatagacaaattagctgattatcttagtcaacagagctatttgtatcatacctta
gataagccaattatttctgactctgattatgataagctgtttagattacttcaagattta
gttaatgacaatccccaatttaagccgataaattcagtattagatcgtgttggaggtgag
gttttagcagggtttgaaactatcaagcataaaaagaaaatgacatctttggcaaatgtt
tttagtctagaggagttgcgtgatttttatgacaagatagagtatgatattgagcttgaa
tgtgaaccaaaaatggacggtctagcaatcagcattttttataaaaatggtaagtttgat
tatgctgttacacgtggtgatggtattcagggtgaaaaagtttcagaaaatgttaaaact
atccgcaatgtcccacttaaactaaatacttcaaaccctccagaagaactagaagttcgt
ggtgagattatcttagataagcaaagttttctatctcttaatgagtatatgcaaactcat
gagaataaaacttttgcaaatccgcgaaatgcagcagctggaagtattcgtatgcttgac
tcaaaagttgtagcaaagcgaccacttaaactttatagctatggtattggctatttttct
aaagactttgtatatcctgaaacccagtttgaactaatgcagctactccaaagttttggc
tttacaattagtgataatatgtttttggcaaaaaatttctcagaggttgaggagtatcac
cataagatgagtcatcagcgtgctgatttagcttatgatattgatggtttagtttttaag
gttaataatattaaactacaagatacaattggctacactgctagaggacctaagtgggct
atagcatataagttcccagctgaagaggtggagtcagaagtgctaaatgtagaattccaa
gttggcagaaccggagcaattacgccagtagcaagacttaagccagtcgcagttggcggc
gtaatagtttcaaatgcaaccttgcacaatatcaatgaaattaaacgcaaagatatccga
gttggtgatagagtaatcgtacgtagagcaggagatgtaattccagaagtggtcaaaagc
ttaccacaatatcgtaagtctgatgcacagatggttgaaatgccaacaaattgtccagtt
tgtgattcaaagattgagaatgttaatgatcaggctatatatcgttgtacaggaggatgg
cattgtcaggcacaaactactgagcgcttgaagcacttcgtctcacgtaaagcaatggat
attgataagcttggagctaaactaattgaacaacttgttgctgcaaatttaattaagtat
cctgctgatatttacaaactcaattttgagcaattgacaggcttagaaagaatggctgct
aaatcatcacaaaatgtcttagactctatcacaaaaagtaaagagccaagtttagcaagg
tttatttttgcaatagggattaaagatatcggtgaagtatcatcagacgctttagcgaat
cattttggtagtctagagagcttccgtgatgctaagtttgaggagctaatagagattaat
gatattggtgagattatggctaataatattgtttcattttggcatgattctctaaatatt
aagattgtagaagagtttttagctattgggattaagatacaaaatccagtaaaagttgaa
cacgcctataacgagagcttcacaggtaaaactgttgttattactgggtcttttgagaac
tatggtcgtacagaacttacacagcttcttaagtcaatcggggcaaaagttacctcaagt
gtttctaaaaaaactgacatggttatttgtggcgataatgctggtagcaaacttacaaaa
gcccaagaattaggtgtagaagttattcttgaagataatctgaaagatttattatga

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