Francisella tularensis subsp. tularensis WY96-3418: FTW_0808
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Entry
FTW_0808 CDS
T00495
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ftw
Francisella tularensis subsp. tularensis WY96-3418
Pathway
ftw00010
Glycolysis / Gluconeogenesis
ftw00020
Citrate cycle (TCA cycle)
ftw00620
Pyruvate metabolism
ftw00785
Lipoic acid metabolism
ftw01100
Metabolic pathways
ftw01110
Biosynthesis of secondary metabolites
ftw01120
Microbial metabolism in diverse environments
ftw01200
Carbon metabolism
ftw01210
2-Oxocarboxylic acid metabolism
Module
ftw_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ftw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
FTW_0808 (aceE)
00020 Citrate cycle (TCA cycle)
FTW_0808 (aceE)
00620 Pyruvate metabolism
FTW_0808 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FTW_0808 (aceE)
Enzymes [BR:
ftw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
FTW_0808 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ABO46680
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Position
784248..786929
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AA seq
893 aa
AA seq
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MSDFTKDIDVLETQEWLEAFEDVIKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNY
VNSIDVSEQPSYPGDIELEQKIEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEV
GFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITAEQLENFRKQAFNGQNAVSSY
PHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPE
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSD
WDKLLQDPRGGKKLAQRLSELNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDI
QALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYGLGEWGESKNIAHNVKKLDTD
ALEHIKNRFNVPASKEDIENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALEIP
SYKDFAKSLLDDSGDREFSTTTAFVRILSHLAKDKNLGKHIVPITVDESRTFGMEGLFRQ
LGIYNPHGQQYVPEDKQQVMFYKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIP
FMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLNGEGLQHEDGHSHIQAGLIPN
CISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYSHRAMPEGCEEGIIKGLYK
LDEEKKPASKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVARA
NMLHPTAEKKESYIEKCFKNEQGPVIASTDYIKLYTDQLREFIPHAFVNLGTDGFGRSDT
RAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEKYNIDPERMAPFYS
NT seq
2682 nt
NT seq
+upstream
nt +downstream
nt
atgtcggatttcactaaagatattgatgttttagaaacccaagaatggcttgaggctttt
gaagatgtcataaaaagagaaggtgctgatagagccaagtttttatttgaacaattactt
gctaaaggttccgagcttggtataaaaagtgcttactcaactgctaaagttaagaactat
gtcaactctatagatgtctctgaacaaccaagttatccaggagatatagagcttgaacaa
aagattgaagctatcaatagatggaactctacagttatagtagctgcagctaataagaaa
gatggttctataggtggacatattggtactggtgccggcgctatgacgctttatgaagta
ggtttcaaccatttttggaaagcacccaatgatgaacatgctggtgatttgatattctat
caaggacatctttctcctattgtttatgcgcgttcattcctagaaggtagaataactgca
gaacagttagaaaactttagaaagcaagcatttaatgggcaaaatgcggtatcttcatat
cctcatccttatctacaaccgacttattggcagttcccaactgtttctatggggttagga
ccacttcaagctatttatcaagctagatttatgaagtatctagaggctaggggtttagca
aaaacatctgatcgcaaagtttgggcattctgtggtgatggcgagatggatgagccagaa
tcaattggttctatcactagagcaggtcgtgaagggctggataaccttatatttgtagtt
aattgtaatctacaaaggctagatggtctggtaaatggtaatggtaatattgttgaagaa
ttagcagatgtatttgctggtgctggttggaatgttatcaaggtgttgtggagtagtgac
tgggataaattattacaagatccaagaggtggtaaaaaacttgctcaaaggttaagtgaa
ttaaatgatggacaattccatacaattaaagctcatggtggtgctgagtgtcgtagagtt
gtctttagcggtgatgaagatttagaagcgctagctaaggatatgacagatgatgatatt
caagcattacgtcgtggaggccatgatccattgaaaatttatgcagcatataagaaggcg
gtagagaatccaaatggtcgtccaacactaattcttcctatgactgttaagggctatggt
ttaggggagtggggtgagtcaaaaaatattgcccacaatgtcaaaaaacttgatactgat
gcacttgagcacatcaaaaatagattcaatgtcccggcttcaaaagaggatatcgaaaac
tatagactcatcaagctagatgaaaattcgcctgagatgaaatatctacactctaagaga
aaagacctaggtggttatattcctaagagattggagaataagcaagcattagagattcca
agctataaagattttgctaagagcttattggatgatagtggtgatagagaattttcaact
actaccgcatttgtaagaatattatcccacttggcaaaagataagaatctagggaagcat
attgtaccaatcacggtagacgagtcacgtacttttggtatggagggcttgtttaggcag
ttaggtatctataacccacatggtcagcaatatgtgccagaagataaacagcaagtaatg
ttctataaagagtctgtagatggtcagattttacaagaaggtattaatgagcaaggaggt
ttttgttcttggattgccgcagctacttcatatagcgtacacaaggttccaatgattcct
ttcatgatttactactcaatgtttggtttccaaagatttggtgatcttgcttgggcagct
ggcgattcgatggcaaaaggttttgtaattggtgggacttcaggacgtacaactctaaat
ggcgaaggtttgcagcatgaagatggtcatagccatatccaagctggtcttatacctaat
tgtatctcttatgatcctacatatgcttatgaattagctgtaatccttggcgaaggtatg
aagagaatgtatgttgatggtgatcatgtatattactatattacagtaatgaatgagaac
tactctcatagagcgatgccagagggctgtgaagaaggtatcatcaagggcttatataag
ttagatgaagagaaaaagccagcatctaagcatgtacagctattgggttctggttctatt
ctaagagaagttgaagctgcagctaagatgctaaaagaagagtatggaattacttctaat
gtttggagtatgacttcagcaaatgagctttatagagaagctaaagatgtagctagagct
aatatgcttcacccaacagcagagaaaaaagaaagctatatcgagaagtgctttaaaaat
gagcaaggtcctgtaatcgcttctacggactatattaagctttatactgatcagttaaga
gaatttataccgcatgcttttgtgaacttaggtacagacggctttggtagatctgatact
cgagcagcgctaagaagtttctttgaggttgatagatatcatgtcgttgttgcttcatta
tatgctctatatttagatggcaaagttgaggctagcgaagttaaagctgcgattgagaag
tacaatatagatccagagcgtatggcacctttttatagctaa
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