Gambusia affinis (western mosquitofish): 122823917
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Entry
122823917 CDS
T07758
Symbol
itchb
Name
(RefSeq) itchy E3 ubiquitin protein ligase b
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
gaf
Gambusia affinis (western mosquitofish)
Pathway
gaf04120
Ubiquitin mediated proteolysis
gaf04144
Endocytosis
gaf04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
gaf00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
122823917 (itchb)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
122823917 (itchb)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122823917 (itchb)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
gaf04131
]
122823917 (itchb)
04121 Ubiquitin system [BR:
gaf04121
]
122823917 (itchb)
Enzymes [BR:
gaf01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
122823917 (itchb)
Membrane trafficking [BR:
gaf04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
122823917 (itchb)
Ubiquitin system [BR:
gaf04121
]
Ubiquitin ligases (E3)
HECT type E3
122823917 (itchb)
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Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
122823917
NCBI-ProteinID:
XP_043960302
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All DBs
Position
LG01:19999327..20022747
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AA seq
873 aa
AA seq
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MASGVTKSSTSNGYPLKAQLQITVLSAKLKENKKNWFAPSPYVEVTVDGQSKKTEKCNNT
HSPKWKQPLTVIVTPFSKLVFRVWSHQTLKSDVFLGMALLDISETLKSNDMKISDLVQSL
QLHTDREHSEMVGDLSVCLNGMTVDPEMFASAEADHCSTSNGESSQHNGDPAVRSSRDSS
PAVDTDHRSSPSTQSTVSSKGSPSVGGRPTRPPRPSRPPPPTPRRPTASPASSTNGMVPT
EANQSQAASDTPVRTPSPSSAPDSSPSTSSNRSSMPATRQPTTPSFPPRASPANVGLLPP
GWEQRVDQNGRLYYVDHIEKRTTWERPEPLPPGWERRFDQMGRVYFVDHITRTTTWQRPT
VETVRNYEQWQHQQSQLQGAMQQFNQRFIYGVQDQAAASQNKEYDPLGPLPAGWEKRTDG
NGRVYFVHHQTRSTQWEDPRTQGLLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPR
TGKSSLENGPRITYVRDFKAKVQYFKFWCQQLSLPQHVKITVTRKNLFEDSFQQIMSINP
QDLRRRLWIIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYGLQINPASNI
NPDHLKYFKFIGRFIAMALFHGKFIDTGFSLPFYKRMLNKPLTLNDLESIDPEFYNSLMW
IKDNDIEECGLEMFFSVDKEMLGEVSTHELKEGGGDIQVTEENKEEYIKLVAEWRLSRGV
EEQTQAFFEGFNEVLPQQYLQYFDAKELEVMLCGMQELDLGDWQNNTIYRHYTRTSKQIV
WFWQLMKEMDNEKRMRLLQFVTGTCRLPVGGFANLMGSNGPQKFCIEKVGKENWLPRSHT
CFNRLDLPPYKSYEQLKEKLMFAIEETEGFGQE
NT seq
2622 nt
NT seq
+upstream
nt +downstream
nt
atggctagtggagtcaccaaatcaagcacctccaatgggtatccactgaaggcacagcta
cagatcacagtgctatcagcaaaactgaaagaaaacaagaagaactggtttgctcccagt
ccttatgtggaagtgacagttgacgggcaatccaagaaaacagagaaatgcaacaacact
cacagccccaaatggaaacagccactcactgtgatcgtgactccattcagcaaactggtg
tttcgtgtgtggagccaccagaccttgaagtcagacgtgtttttaggtatggccttgctg
gacatcagcgagactctcaagtccaacgatatgaaaatttctgatctggtgcagtcactc
cagctgcacactgacagagagcactcagaaatggtgggggacctgtccgtctgtctgaac
ggaatgacggtggacccagaaatgttcgcctcagcagaagccgaccactgcagtacatct
aatggagaatcatcacagcacaatggggatcctgccgtaaggtcaagtcgagacagctct
ccagctgtggacactgatcacagatcctctcccagcacccagagtacagtgagcagcaaa
gggtctccatcagtgggaggacggcccacccgaccacccagaccctccaggcctcccccc
ccaacaccccgcagaccaactgcttcaccagcatcttctaccaatgggatggttcccacg
gaggctaaccagagccaggcagcctctgatacaccggtgcggaccccaagtccctcatct
gctccggactcaagcccatcgacgtcctcaaataggagctccatgccagcaaccagacag
ccgaccacgccttctttccctcccagagcatcacccgccaatgttggactattgcctcct
ggatgggagcagagggtggatcagaatggcaggttgtattacgtggatcacattgaaaag
agaacaacatgggaacgtcctgagccgctcccccctgggtgggagcgtcgttttgaccag
atgggccgtgtctactttgttgatcacatcacgcgaaccaccacatggcagcggcccacg
gtggagacggtgcgtaattacgaacagtggcaacaccagcagagccagctgcagggcgcc
atgcagcagttcaaccagaggttcatctatggggttcaagaccaggcagcagcttctcag
aataaagagtatgatcctctcggccctctgcctgctgggtgggaaaagaggacagatggc
aacggaagagtttattttgtccatcaccagacccgctcaactcagtgggaggaccctcga
acgcagggattactgaacgagaagccgcttcctgaaggctgggagatgagattcaccgtg
gatggcattccttattttgtagaccacaacaggagaacgaccacctatattgaccctcgc
acggggaaatcctctcttgaaaacggaccacggatcacttatgttcgagacttcaaagcc
aaagttcagtatttcaaattctggtgccagcaactgtctttgcctcagcatgttaaaatc
acagtaacgaggaaaaacctctttgaggattctttccagcagataatgagcattaaccct
caggatttgagaagaaggctttggatcatcttcccaggagaggaaggccttgactacgga
ggcgttgccagggagtggttcttcttgttgtctcatgaggttttgaaccccatgtactgc
ctgtttgaatacgctggtaaagataactacggtctccaaatcaaccctgcttcaaacatc
aaccccgaccacctcaagtatttcaagtttattggacgattcattgcaatggctcttttc
catggcaagttcatcgacactggtttctctctgccattttacaaacggatgctcaacaaa
cctttgacactcaacgatctggagtcaatagatcctgagttttataactccctcatgtgg
attaaggacaatgacattgaggagtgtgggttggaaatgttcttctcagttgataaagaa
atgctcggagaagtatccacccatgagcttaaagaaggtgggggagacatccaagttacc
gaggaaaacaaggaggagtacatcaagttggtagcagagtggcggctgtccagaggagta
gaagaacagacccaggcgttctttgagggcttcaatgaggtcctccctcagcagtacctg
cagtattttgatgctaaagagctcgaggtcatgctgtgtggcatgcaagaactggatctg
ggggactggcagaacaacaccatctacagacactacactcgtaccagcaaacagatcgtc
tggttctggcagttgatgaaagagatggacaacgagaagcggatgaggctgttgcagttt
gtaaccggcacttgtcgtctgcctgtgggaggcttcgccaaccttatggggagcaacggg
ccacagaagttctgcattgagaaagtgggaaaggaaaactggctgcccagaagtcacaca
tgcttcaacagattggacttgccgccctataagagctacgaacaactcaaggagaagctg
atgttcgctatcgaggagacggaaggattcggacaggagtga
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