Gambusia affinis (western mosquitofish): 122839771
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Entry
122839771 CDS
T07758
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
gaf
Gambusia affinis (western mosquitofish)
Pathway
gaf00140
Steroid hormone biosynthesis
gaf01100
Metabolic pathways
Module
gaf_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
gaf_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
gaf_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
gaf00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
122839771 (hsd3b1)
Enzymes [BR:
gaf01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
122839771 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
122839771 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
NmrA
KR
RmlD_sub_bind
adh_short
Ldh_1_N
Motif
Other DBs
NCBI-GeneID:
122839771
NCBI-ProteinID:
XP_043987663
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Position
LG11:complement(5382836..5392990)
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AA seq
374 aa
AA seq
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MSLRGDVCVVTGACGFLGKRLVQLLLEEEKASEIRLLDRDVQKQVLESLEDCRGETTLSV
FEGDIRDGDFLKKALRGASTVFHIASLIDVTESMEYSEMYGVNVKGTQLLLEACIQENVA
SFIYTSTVEVMGPNPRGEPIINGTEDTVYDTTLKFNYSKTKKEAEDRTLQANGETLLNGG
RLSTCALRPTYIYGDGCRFLLYHMGDGIRNKNVLFRMSVPEAHVNPVYVGNVAFAHLQAA
RGLKDPLKRNVIGGRFYYLSDDTPPMSYSDFNHVLMSPLGFSIQDKLVLPLRLFYILCFL
LEALCTILRPFVRIVPPMNRQLLTLLNTSFTFSYEKAKKDLGYVPRYSWEEARRRTTEWL
ASQLPAEREKIMSS
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgagaggtgatgtttgcgtggtgacgggagcctgtggattcctggggaagagg
ctcgtccagctgcttctggaagaggagaaagcgtccgagatccggctgctggacagagac
gtgcagaagcaggttttggagagtctggaagactgcagaggcgagacaacgctgagcgtc
ttcgagggcgacatcagagacggggatttcttgaaaaaagccttgcgtggcgcatcgacc
gtcttccacatcgcttccctcatcgacgttaccgagtccatggagtacagcgagatgtac
ggagtcaacgtcaaaggaactcagctgcttttggaggcgtgtatccaagagaacgtggcc
tctttcatctacaccagcacggtggaagtgatgggcccaaacccccgaggggagccgata
atcaacggcaccgaggacacggtttacgacaccaccctgaagttcaactacagcaagacc
aaaaaggaggcagaggacagaacccttcaggccaacggcgagacgctcctaaacggaggc
cgcctctccacctgcgccctcaggcccacgtacatctacggggacggctgccgcttcctg
ctgtaccacatgggcgacggcatacgaaacaagaacgttctctttcgcatgtccgtgccg
gaggcccacgtgaacccggtctacgtgggcaacgtggccttcgctcacctccaggcagcc
cgtggccttaaagatccactaaaaagaaacgtgatcggagggaggttttactacctctcc
gacgacaccccacctatgagttactcggacttcaatcacgttttgatgtctcccctcggc
ttcagcattcaggacaaactcgtgctgccgctccgcctcttctacatcctgtgcttcctc
ctggaagcgctctgcacgatcctgcgaccgtttgtgcgcatcgtgccgccgatgaaccgg
cagctgctcaccttgttgaacacttcgtttaccttctcctacgagaaagccaagaaggac
ctgggctacgtcccccggtacagctgggaggaagcgcgcagacgcaccaccgaatggctc
gcctcgcagctgccagcggagagggaaaaaatcatgtccagctaa
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