Gracilinanus agilis (agile gracile opossum): 123233053
Help
Entry
123233053 CDS
T07702
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas00562
Inositol phosphate metabolism
gas01100
Metabolic pathways
gas01521
EGFR tyrosine kinase inhibitor resistance
gas04068
FoxO signaling pathway
gas04070
Phosphatidylinositol signaling system
gas04071
Sphingolipid signaling pathway
gas04115
p53 signaling pathway
gas04140
Autophagy - animal
gas04150
mTOR signaling pathway
gas04151
PI3K-Akt signaling pathway
gas04218
Cellular senescence
gas04510
Focal adhesion
gas04931
Insulin resistance
gas05165
Human papillomavirus infection
gas05166
Human T-cell leukemia virus 1 infection
gas05200
Pathways in cancer
gas05206
MicroRNAs in cancer
gas05208
Chemical carcinogenesis - reactive oxygen species
gas05213
Endometrial cancer
gas05214
Glioma
gas05215
Prostate cancer
gas05218
Melanoma
gas05222
Small cell lung cancer
gas05224
Breast cancer
gas05225
Hepatocellular carcinoma
gas05230
Central carbon metabolism in cancer
gas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
gas05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
123233053 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
123233053 (PTEN)
04070 Phosphatidylinositol signaling system
123233053 (PTEN)
04071 Sphingolipid signaling pathway
123233053 (PTEN)
04151 PI3K-Akt signaling pathway
123233053 (PTEN)
04150 mTOR signaling pathway
123233053 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
123233053 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
123233053 (PTEN)
04218 Cellular senescence
123233053 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
123233053 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123233053 (PTEN)
05206 MicroRNAs in cancer
123233053 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
123233053 (PTEN)
05230 Central carbon metabolism in cancer
123233053 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123233053 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
123233053 (PTEN)
05214 Glioma
123233053 (PTEN)
05218 Melanoma
123233053 (PTEN)
05215 Prostate cancer
123233053 (PTEN)
05213 Endometrial cancer
123233053 (PTEN)
05224 Breast cancer
123233053 (PTEN)
05222 Small cell lung cancer
123233053 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
123233053 (PTEN)
05165 Human papillomavirus infection
123233053 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
123233053 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
123233053 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123233053 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
gas01009
]
123233053 (PTEN)
Enzymes [BR:
gas01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
123233053 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
123233053 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
123233053 (PTEN)
Protein phosphatases and associated proteins [BR:
gas01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
123233053 (PTEN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PTEN_C2
Tc-R-P
DSPc
PTP-SAK
PTP-NADK
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
123233053
NCBI-ProteinID:
XP_044515163
LinkDB
All DBs
Position
2:718590372..718668424
Genome browser
AA seq
404 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDATKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSH
LLKHHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYTSPSGPTRREDKYMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEENSDKVENGSLCGDQE
IDSICSAERSDNDKEYLILTLSKNDLDKANKDKANRYFSPNFKVKLFFTKTVEEPSNPEA
SSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1215 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaggagatcgtgagcagaaacaaaaggagataccaggaggatgga
ttcgacttggacttgacctatatttatccaaacatcattgctatggggtttcctgcagaa
aggcttgaaggcgtgtacaggaacaacattgatgatgtagtcaggtttttggattcaaag
cataaaaatcattacaagatatacaatctatgtgctgaaagacattatgatgccaccaaa
tttaactgtagagttgcacagtatccttttgaagaccataacccgccccagctagagctc
atcaagcctttctgtgaggacctggaccagtggctaagtgaagatgacaatcatgttgca
gcaattcattgtaaagcaggaaagggacggactggggtcatgatctgtgcgtatttatta
catcgaggaaaatttttaaaggcccaagaggctctagatttctatggggaagtcaggacc
agagacaaaaagggagtaaccattcccagtcagaggcgctatgtctattattatagccac
ctgttaaagcatcacttggactacagaccggtggccctgctatttcacaagatgatgttt
gaaacgattccgatgttcagtggtggaacttgcaatcctcagtttgtggtctgccagctg
aaggtgaagatttacacatctccttcaggacccacaaggcgggaagacaagtatatgtac
ttcgagtttccccagcctttgccagtgtgtggtgacattaaagtggaattcttccataag
caaaacaagatgctcaagaaggacaaaatgtttcacttttgggtaaatacattcttcata
ccaggaccagaggaaaactcagacaaagtagaaaatggaagtctttgtggtgatcaagaa
attgatagtatttgcagtgccgagcggtcggataatgacaaggaatatctcatactcacg
ttatccaaaaatgatctagacaaagcaaataaagacaaggccaacagatacttctctcca
aactttaaggtgaagcttttcttcacaaaaactgtagaagagccgtcaaaccccgaggcc
agcagttccacttcggtcaccccggacgttagtgacaatgagcccgatcattaccgatac
tcggacaccactgactctgacccagagaatgagccttttgatgaagatcagcacacacag
atcacaaaagtctga
DBGET
integrated database retrieval system