KEGG   Gracilinanus agilis (agile gracile opossum): 123236570
Entry
123236570         CDS       T07702                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
gas  Gracilinanus agilis (agile gracile opossum)
Pathway
gas00670  One carbon pool by folate
gas00790  Folate biosynthesis
gas01100  Metabolic pathways
gas01240  Biosynthesis of cofactors
gas01523  Antifolate resistance
gas04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:gas00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    123236570 (DHFR)
   00670 One carbon pool by folate
    123236570 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    123236570 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    123236570 (DHFR)
Enzymes [BR:gas01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     123236570 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 123236570
NCBI-ProteinID: XP_044518915
LinkDB
Position
1:333310842..333342826
AA seq 187 aa
MVRTINCIVAVSQNMGIGRHGDLPWPMLRNEFKYFQKMTTTPSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRELKEPPHGAHYLASSLDDALNLLELPELADKVDMVWIVGGSS
VYQEAMKKPGHQRLFITRVLQEFECDTFFPEIDLQKYKLLQNYPGVNTDVQEEKGIQYKF
EVYEKHD
NT seq 564 nt   +upstreamnt  +downstreamnt
atggtccgtacaatcaactgcatcgtcgcggtgtcccagaacatgggcattgggaggcat
ggagacctgccctggcccatgctcaggaatgagttcaagtacttccaaaaaatgaccaca
actccttcagtagaaggcaaacagaatcttgtgataatggggaggaagacctggttctcc
attcctgagaagaatcgaccgctgaaagacagaattaatatagttcttagcagagaactg
aaggaacctcctcatggagctcattatctggccagcagtctggatgatgcattaaacctt
ctcgaacttccagaactagcagataaggtagacatggtttggatagttggaggcagctct
gtttatcaggaagcaatgaagaaacctggccatcagcgcctgtttataacaagagttttg
caagaatttgagtgtgacacatttttcccagaaattgatctacagaaatataaacttctc
caaaattatccaggtgttaatactgatgtccaagaagaaaaaggcattcagtataaattt
gaagtatatgaaaaacatgattaa

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