Gracilinanus agilis (agile gracile opossum): 123237451
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Entry
123237451 CDS
T07702
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas04120
Ubiquitin mediated proteolysis
gas04144
Endocytosis
gas04330
Notch signaling pathway
gas04668
TNF signaling pathway
gas04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
123237451 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
123237451 (ITCH)
04668 TNF signaling pathway
123237451 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
123237451 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
123237451 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
gas04131
]
123237451 (ITCH)
04121 Ubiquitin system [BR:
gas04121
]
123237451 (ITCH)
Enzymes [BR:
gas01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
123237451 (ITCH)
Membrane trafficking [BR:
gas04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
123237451 (ITCH)
Ubiquitin system [BR:
gas04121
]
Ubiquitin ligases (E3)
HECT type E3
123237451 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
123237451
NCBI-ProteinID:
XP_044520316
LinkDB
All DBs
Position
2:complement(348317971..348427614)
Genome browser
AA seq
871 aa
AA seq
DB search
MSGSSSRSGSVGGLTMKSQLQIIVISAKLKENKKNWFGPSPYVEVSVDGQSKKTEKCSNT
NSPKWKQPLTVIVTPISKLNFRVWSHQTLKSDVLLGSAALDIHETLKSNNMKLDEVIVTL
QLVGDKEPTEIIGDLSVCLDGLQVDPEILTNGYATCSEGSSQSDDSRTRNDTRSNTNGPE
NAEEPGCSDNRKVNGSNSPSLTNGGFKPSRPPRPSRPPPPTPRRPASVNGSPAPSETPVS
STDSSPSTSMSVIPEGATAGTSVPTTVALTTPPTSRQVQSVNSASQQLNTVNQGPLPPGW
EQRVDQHGRVYYVDHVEKRTSWDRPEPLPPGWERRVDNMGRVYYVDHFTRTTTWQRPTLE
SVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFTSSQNKEFDPLGPLPPGWEKRTDSNG
RVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTG
KSALDNGPQIAYVRDFKAKVHYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQD
LRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINP
DHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVK
ENNIEECGLEMYFSVDKEILGEIKSHELKPNGSNILVTEENKEEYIRMVAEWRLSRGVEE
QTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWF
WQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCF
NRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2616 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtagttcacggtcagggtctgtggggggattgaccatgaaatcacaactt
cagatcattgtcatttcagcaaaacttaaagaaaataaaaagaactggtttggaccaagt
ccttatgtggaagtctcagtagatggacagtcaaagaagacagaaaagtgcagcaatacc
aacagtcccaagtggaagcaacctcttactgtaattgtcacacctatcagcaaattaaat
tttcgtgtatggagtcaccagacattaaaatccgatgttttactgggaagtgctgctcta
gatattcatgaaacattaaagtcaaataatatgaaacttgatgaagtgattgtgacatta
caactcgtgggtgacaaagagccaacagaaatcataggagacctgtcagtttgtcttgat
ggactacaagtagatcctgagattttaacgaatggctatgccacatgttcagaaggtagt
tcacagagtgatgattccagaaccagaaatgatacaagatcaaatacaaatggacctgaa
aatgctgaggaaccaggatgcagtgacaatagaaaggtcaatggcagcaactctccatca
ctcacaaatggaggttttaaaccttctaggcctccaagaccttcaaggccacctcctcct
actccccgccgaccagcatctgtcaatggttctcctgcaccctctgaaactcctgtatct
agtacagactcatcaccgtcaacaagtatgagtgtaattcctgaaggagcaacagctgga
acatcagttcctaccactgtggctttaacaacacctccaacttctagacaagtgcagtca
gtaaattctgcttctcaacaacttaatacagttaatcaaggtcctcttccacctggttgg
gaacagagagtggaccagcatggacgagtctactatgtagatcacgttgaaaaaagaaca
tcgtgggatagaccagaacctcttcctcctggctgggaacgtcgagttgacaacatggga
cgtgtttattatgttgaccactttacaagaactacaacgtggcagcgaccaactttggaa
tcagttagaaactatgagcaatggcaactacagcgaagtcaactccaaggagcaatgcaa
cagtttaaccagagattcatttatgggaatcaagacttgtttacttcatctcagaataaa
gaattcgatcctcttggacctctgccaccaggatgggaaaagcgaacagatagtaatggc
agagtgtattttgtcaatcacaacacacgtattacacagtgggaagatcccagaagtcag
ggtcaattaaatgagaagcctttaccagaaggctgggaaatgagatttacagtggatggg
attccatattttgtggatcacaataggagaacaacaacatatatagatcctcgaactgga
aaatctgctctagacaatgggccccaaatagcctatgttagagattttaaagcaaaggtt
cattatttccgtttctggtgtcagcaactggctatgccacagcacatcaagattacagtg
acaagaaaaactttgtttgaagattcctttcagcagataatgagtttcaatccccaggat
cttcgaagacgtttgtgggtgatttttccaggagaagaaggtttagattatggaggtgtg
gcaagagaatggttctttcttttgtcacatgaagtgctgaacccaatgtattgcctgttt
gaatatgcaggaaaggataactactgcttgcagataaatccagcttcttatattaatcca
gatcatctgaaatactttcgttttattggcaggtttattgccatggcattattccatggg
aaattcatagacacaggcttttctttgccattttataaacgtatcttgaataaaccagtt
ggactcaaggacttagaatctattgatccagaattttacaattctctcatctgggttaaa
gaaaacaacatagaagaatgtggtttagagatgtacttttcagttgataaggaaattctt
ggtgaaattaagagtcatgaactgaaacccaatggcagtaatatactagtaacagaagaa
aataaagaggaatatattagaatggtagctgaatggagattatctcgaggtgttgaagag
cagacacaagctttctttgaaggcttcaatgaaattctcccacagcagtacctgcaatac
tttgatgctaaagaactagaggtacttctgtgtggaatgcaagagattgacttaaatgac
tggcaaagacatgccatctaccgacattatactaggacaagcaaacaaatcatgtggttt
tggcagtttgtgaaagaaattgacaatgagaagagaatgagactgttgcagtttgttact
ggaacgtgcaggttgccagttgggggatttgctgacctcatggggagcaatggacctcaa
aagttttgcattgaaaaagttgggaaagaaaattggttacccagaagtcacacctgtttt
aaccgcttggatctgccaccctacaagagctatgaacaactgaaggaaaaattgttattt
gccattgaggaaacggaaggatttggacaagagtga
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