Gracilinanus agilis (agile gracile opossum): 123242631
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Entry
123242631 CDS
T07702
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas04022
cGMP-PKG signaling pathway
gas04068
FoxO signaling pathway
gas04081
Hormone signaling
gas04140
Autophagy - animal
gas04152
AMPK signaling pathway
gas04211
Longevity regulating pathway
gas04213
Longevity regulating pathway - multiple species
gas04910
Insulin signaling pathway
gas04920
Adipocytokine signaling pathway
gas04923
Regulation of lipolysis in adipocytes
gas04930
Type II diabetes mellitus
gas04931
Insulin resistance
gas04932
Non-alcoholic fatty liver disease
gas04935
Growth hormone synthesis, secretion and action
gas05010
Alzheimer disease
gas05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
123242631 (IRS2)
04022 cGMP-PKG signaling pathway
123242631 (IRS2)
04152 AMPK signaling pathway
123242631 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
123242631 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
123242631 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123242631 (IRS2)
04923 Regulation of lipolysis in adipocytes
123242631 (IRS2)
04920 Adipocytokine signaling pathway
123242631 (IRS2)
04935 Growth hormone synthesis, secretion and action
123242631 (IRS2)
09149 Aging
04211 Longevity regulating pathway
123242631 (IRS2)
04213 Longevity regulating pathway - multiple species
123242631 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
123242631 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
123242631 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
123242631 (IRS2)
04932 Non-alcoholic fatty liver disease
123242631 (IRS2)
04931 Insulin resistance
123242631 (IRS2)
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GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Mcp5_PH
Motif
Other DBs
NCBI-GeneID:
123242631
NCBI-ProteinID:
XP_044526469
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All DBs
Position
3:510599379..510635491
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AA seq
1383 aa
AA seq
DB search
MASPPQNGLLTPANSSNGGGGGGGTNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGP
GSGSEEQGGGGAGGQPPLPARLEYYENEKKWKNKSGAPKRVIALDSCLNINKRADAKHKY
LIALYTKDEYFAVAAENEQEQEGWYRALTDLLNEGKAAYDSSSLYPHCLSGTSSASASSC
SASLPGSGGSGSFGAAAEDLHYGLITPASAAYREVWQVNLKPKGLGQSKNLTGVYRLCLS
ARTIGFVKLNCEVPSVTLQLMNIRRCGHSDSFFFIEVGRSASTGPGELWMQADDSVVAQN
IHETILEAMKALKELFEFRPRSKSQSSGSSSTHPISVPGTRRHHHHHLVNLPPSQTGLLR
RSRTDSLAATPPTAGAPISTQAPGSGKCNSCRVRTASEGDGSSSGGAGGVGCRPVSVAGS
PMSPGPVRTPLSRSHTLSSSCSASMRPNKMMLAPAGGPLQHSRSMSMPVSHSPPSATSPG
SLSSSSGHGSASYSLPQGQHQHPHHLHHHQGQRPSSGSASASGSPSDPGFMSLDEYGSSP
GDLRAFCSNRSNTPESIAETPPARDGSGTELYGYMTMERPLSLCGRTYRRVSGEGALDLD
KGHRKRTYSLTTPARQRAVPQVSSASLDEYTLMRASFAGSSSRLYPASSPKVTYNPYPED
YGDIEIGSHRSSSSNLGADDGYMPMTPGVAPLAGGSIGSCKSDDYMPMSPTSVSAPKQIL
QPRMAAASLATGAASQTASSATSGRGSPLNGSSYKTSSPAESSPEDSGYMRMWCGSKLSV
ESSEGKLLPNGDYLNMSPSDAGASLTPPDFFYDSVPLPGGGEPPKGAPGCCYSSLPRSYK
TPCPRNGDSDQYVFMNSPVGRRIVEEEQEQPSLQPLPNTTTPCTQPTRPFVSNGGSHSQP
HHLVPSTVRQSGSSSGNNNRPESFLIQRCRAVRPTRLSLEGLRTLPSMHEYPLPPEPKSP
GEYINIDFSESGAHLSPPPPPLLTSAASSSSLLSASSPASSMGSGTPGTSGDSRRRSPLS
DYMNLGFGSPKSPKSGTEGGGSVGSLDALMSPEASSPCPPLPTPPASSSTSSSQQQQLPP
PPPGELYRLPPASSTCHPTPVSASSPSSPPETEDSGDYTEMAFGIAATPPQPIAAPPKPE
SARVTSPTSGVKRLSLMEQVSGVEAFLLASPPPDPHRGAKVIRADPQGGRRRHSSETFSS
TTTVTPVSPSFAHNPKRHNSASVENVSLRKSGEGPNGNGGESLGGGEEEPSTSPHLRQPS
LPLPPQSQQLRWTQNQPGALVGCPGSSGSPMCRETSAGFQNGLNYIAIDVRDEAGLLLQQ
QQQSGDKNSWALTRGLSGLINGGSGSSTGGCVGPGSGPLPTTNTYASIDFMTHHLKEATA
VKE
NT seq
4152 nt
NT seq
+upstream
nt +downstream
nt
atggccagcccgccacagaacgggctcctgacccccgcgaattcctccaacggaggagga
ggtggcggcggcaccaacctcaataacaacaacaacaacaacaaccacagcgtgcggaag
tgcggctacctgaggaagcaaaaacatgggcacaaacgctttttcgtgcttcggggccct
gggagcggcagcgaagagcagggcggtgggggagccgggggccagccacccctgcccgcg
aggctggagtactatgagaatgagaaaaagtggaagaacaagtcgggggccccgaaaagg
gtgatcgccttagactcttgcctcaacatcaacaagcgggcggatgccaagcacaagtat
ctgatcgccctctacaccaaggacgagtacttcgctgtggcagccgaaaatgaacaggag
caggagggctggtaccgagcgctcacggacctgctcaacgagggcaaagccgcctacgac
tcgagctctctctacccgcactgcctgtccggcacctcatcggccagcgcctcgtcctgc
agcgcctccctgcctggttcgggcggcagtggctctttcggggcagcagctgaagatctc
cactacggactgatcaccccggccagcgcggcgtaccgggaggtctggcaggtgaacctg
aaacccaaaggactggggcagagtaagaatctgaccggggtgtatcggctttgcctctct
gcgcgcactatcggttttgtaaagctcaactgtgaggtgccttcggtcaccctacagctg
atgaacatccggcgctgtggccactcggacagctttttcttcattgaagtgggacgctct
gcgtccaccggcccgggtgagctctggatgcaggcggatgactccgtggtggcccagaac
atccatgaaaccatcctggaggccatgaaagccctaaaggagctgttcgaattccgtccc
cgaagcaaaagtcagtcttcgggctcctcttccacccaccccatcagcgtccctggcacc
cggcgtcaccaccaccatcatctggtaaacctgccccccagccagactgggctcctgcgt
cgctcccgaaccgacagcctggccgccacgcctcccaccgccggcgcccccatttcgacc
caggctccaggatctgggaagtgcaactcctgtcgggtacgcacggccagtgagggcgat
ggcagtagcagcggcggtgcaggaggggtgggctgcaggccagtttcagtggccggcagc
cccatgagtcccggcccggtgaggactcccctgagtaggtcccatactctgagcagcagc
tgcagcgcctccatgcgacctaataagatgatgttagccccagcgggggggcccctgcaa
cacagccgatccatgtctatgccggtgtcccattcgcctccgtctgccaccagccctggc
agcctctcctccagcagcgggcatggctcagcttcttactccctgcctcaaggacagcat
caacatccacaccaccttcaccaccaccagggccagaggccctctagtggcagtgcttct
gcttctggctcccccagtgacccaggcttcatgtccttggatgagtacggctctagccct
ggggacctgcgggccttttgcagcaaccgaagcaacactcctgagtccattgctgagacc
ccaccagcgagagatggcagtgggactgaactatatggatacatgaccatggagagaccc
ctaagcctttgtggccgaacctaccgaagagtgtctggggaaggggccctagatttggac
aaaggtcacagaaagaggacttattctctgaccacacctgctcgacaacgtgcagtgccc
caagtctcctctgcctcccttgatgaatatactctgatgagggccagttttgcgggcagt
tcaagccgcctttatccagcctcttctcccaaagtgacctacaacccatacccagaggac
tatggggacattgagattggctcccatcggagctccagcagtaaccttggagcagatgat
ggctacatgcccatgactcctggagtggccccactggcagggggcagcattggaagctgc
aaaagtgatgactacatgcccatgagtcccaccagtgtctctgctcccaaacaaatactg
cagccacggatggcagcagcctctttggctacaggtgcagcatctcaaacagcctcatca
gcaacaagtggaagaggctccccgctgaatggtagcagctacaagaccagttctccagct
gaaagctctcctgaggatagtgggtacatgcggatgtggtgtggttccaagctctcagtg
gagagctctgaaggcaagctacttcccaatggagattaccttaacatgtcccctagtgat
gcgggagcttctcttaccccacctgacttcttctatgattcagtcccattgcctggtggt
ggagaaccaccaaagggagccccaggctgctgttatagttcactgccccgttcttataaa
actccctgtcctcgaaatggggatagtgaccagtatgtattcatgaattctccagtgggg
aggaggattgtggaagaggagcaagagcagccaagtctgcagccactgcccaacacaact
accccctgtacccagcctactaggccctttgtatctaatgggggcagccactcccaacct
caccacctagtgccttcaacagttaggcagagtggcagtagcagtggcaacaataaccgt
ccagaaagtttcctcattcagcgttgcagagcagtccggcccactcggctgtccctagag
gggcttagaacccttccaagcatgcatgaatatccactaccacctgagcccaaaagccca
ggtgagtacatcaacattgactttagtgaatctggagcccacctctcaccacctccacct
cccctgctaacttcagcagcctcatcttcatcactactctcagctagcagccctgcctct
tcaatgggttcaggtacccctggcaccagtggtgacagccggaggcgctctcccctctct
gattatatgaaccttggctttggctcacccaagtcacccaaatctggcactgagggtggt
ggctctgtgggctctttggatgccttgatgtcccctgaggcttcctcaccctgcccacca
ctgccaacaccacctgcctcctcctctacttcctcctcacagcagcagcaactaccacct
ccaccaccaggagagctgtaccgcctgcctccagcttcttctacctgccacccaacccct
gtctctgcctcctccccttcttctccccctgagacagaggatagtggtgactacaccgag
atggccttcggcatagccgccactccaccacaacccattgcagcacctccgaagccagaa
agtgcccgggtgaccagccctacatctggtgtgaagcgactgagtttgatggagcaggtg
tctggtgtagaggccttcctcctggccagcccacccccagatccacaccggggtgccaag
gtcatccgtgctgacccacagggtggccgcagacgccacagctcggaaaccttctcctcg
accactactgtgacccctgtgtccccatccttcgcgcacaatcctaagcgccacaattcg
gcctctgtggaaaatgtctctctcaggaaaagtggcgaagggcccaatggcaatggtggt
gagagtcttggaggaggtgaggaagagccatccacatctcctcaccttcggcaaccatca
ctccctctgccacctcagtctcagcagctgaggtggacacaaaaccaacctggagcatta
gttggttgccctgggagcagtggctctcctatgtgtcgggagacatcagcaggcttccag
aatggtctcaactacattgccattgatgttagagatgaagctggcttattgttacagcag
cagcagcagtctggagacaagaattcctgggccctgacccgtggcctcagtggcctcatc
aatggtggaagtggcagcagtacaggtggttgtgtggggccaggctctggacccttgccc
acaaccaacacctatgctagcattgacttcatgacccatcacctgaaggaggctacagct
gtgaaagagtga
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