Gracilinanus agilis (agile gracile opossum): 123243232
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Entry
123243232 CDS
T07702
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas04064
NF-kappa B signaling pathway
gas04380
Osteoclast differentiation
gas04650
Natural killer cell mediated cytotoxicity
gas04658
Th1 and Th2 cell differentiation
gas04659
Th17 cell differentiation
gas04660
T cell receptor signaling pathway
gas05135
Yersinia infection
gas05166
Human T-cell leukemia virus 1 infection
gas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
gas05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
123243232 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
123243232 (LCK)
04660 T cell receptor signaling pathway
123243232 (LCK)
04658 Th1 and Th2 cell differentiation
123243232 (LCK)
04659 Th17 cell differentiation
123243232 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
123243232 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123243232 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
123243232 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
123243232 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
123243232 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gas01001
]
123243232 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
gas03036
]
123243232 (LCK)
Enzymes [BR:
gas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123243232 (LCK)
Protein kinases [BR:
gas01001
]
Non-receptor tyrosine kinases
SRC family
123243232 (LCK)
Chromosome and associated proteins [BR:
gas03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
123243232 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
Kdo
SH2_1
DUF4390
SH3_3
SH3_16
RIO1
Motif
Other DBs
NCBI-GeneID:
123243232
NCBI-ProteinID:
XP_044527381
LinkDB
All DBs
Position
3:complement(75090070..75111092)
Genome browser
AA seq
458 aa
AA seq
DB search
MGCCCSSSLDEDWMENIDVCERCHYPIVPLDAKDTLPMRNGSDVRDPLVTYDGLDPPVSP
LQDNLVIALHSYKPSHDGDLGFEKGEQLKILEQNGEWWKAQSLTTGQEGFIPFNFVAKVN
SLEPEPWFFKDLSRKDAERQLLAPGNTHGSFLIRESETTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFPGLHELVQHYSRYYNGHTKVAVKSLKAGSMSPDAFLAEANL
MKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTSTGVKLTIHKLLDMAAQIAEG
MAFIEERNYIHRDLRAANILVSDTLNCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEA
INYGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTNPEVIQNLEQGYRMVRPDNCPEELYK
LMMLCWKERPEERPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgggctgctgctgcagctccagcctcgatgaggactggatggaaaatattgatgtgtgc
gaacgatgccactaccctattgttccattggatgctaaggacacgctcccaatgaggaat
gggtctgatgtgcgggatcccttggtcacctatgatggcttggacccacctgtgtctccg
ttacaagataacctggtcatcgccctgcacagttataaaccctcccatgatggggacctg
ggctttgagaagggggagcagctaaagatcctggagcagaacggagaatggtggaaggca
cagtccctgaccactggccaggagggcttcattcccttcaactttgtggccaaagttaac
agcctggagcctgagccttggtttttcaaggacctgagccggaaggatgctgagagacaa
cttctggcccctgggaacacccatggatccttcctgatcagagagagtgagacaacagca
ggttccttctcactctcagtgcgagactttgaccagaaccagggggaagtggtgaaacat
tacaagatccgcaatctggacaatggtggcttctacatttccccccgaatcacctttcct
ggtctgcatgagctggtccagcattactctaggtactataatggacacaccaaggttgca
gtgaaaagcctaaaagcgggcagcatgtcccctgatgccttcctggctgaggccaacctg
atgaaacagttgcagcaccaacggctggtccgcctatatgcagtggtcacgcaggagccc
atctacatcatcacagaatacatggagaacgggagcctggtagacttcctcaaaacctca
actggggtcaaactaaccatccataaattgctggatatggctgcacagattgctgagggc
atggccttcattgaggagcggaattacatccaccgagaccttcgggcggccaacatccta
gtgtcagacacactcaactgtaagattgctgactttggcttggcccggctaattgaggac
aatgagtacacagccagggagggagcaaaatttcccatcaagtggacagctcctgaagcc
atcaactatgggacattcaccatcaagtcagatgtctggtcttttggcatcctgctcaca
gaaattgtcacctatgggaggattccctacccaggaatgaccaaccccgaggtgatccag
aacctggagcaaggttatcggatggtgaggccggacaactgcccagaggagctgtacaaa
ctgatgatgctgtgctggaaggaaagacccgaggagcgacctacctttgactacctgagg
agtgtattagaggacttcttcactgccacagagggccagtaccagccccagccatga
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