Gracilinanus agilis (agile gracile opossum): 123245322
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Entry
123245322 CDS
T07702
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas01524
Platinum drug resistance
gas03440
Homologous recombination
gas03460
Fanconi anemia pathway
gas04120
Ubiquitin mediated proteolysis
gas04151
PI3K-Akt signaling pathway
gas05206
MicroRNAs in cancer
gas05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
123245322 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
123245322 (BRCA1)
03460 Fanconi anemia pathway
123245322 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
123245322 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
123245322 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
123245322 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
123245322 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
gas01009
]
123245322 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
gas04121
]
123245322 (BRCA1)
03036 Chromosome and associated proteins [BR:
gas03036
]
123245322 (BRCA1)
03400 DNA repair and recombination proteins [BR:
gas03400
]
123245322 (BRCA1)
Enzymes [BR:
gas01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
123245322 (BRCA1)
Protein phosphatases and associated proteins [BR:
gas01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
123245322 (BRCA1)
Ubiquitin system [BR:
gas04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
123245322 (BRCA1)
Multi subunit type E3
BRCC complex
123245322 (BRCA1)
Chromosome and associated proteins [BR:
gas03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
123245322 (BRCA1)
DNA repair and recombination proteins [BR:
gas03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
123245322 (BRCA1)
BRCA1-A complex
123245322 (BRCA1)
BRCA1-B complex
123245322 (BRCA1)
BRCA1-C complex
123245322 (BRCA1)
BRCA complex
123245322 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
123245322 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
BRCT_2
Motif
Other DBs
NCBI-GeneID:
123245322
NCBI-ProteinID:
XP_044530105
LinkDB
All DBs
Position
4:188656393..188710445
Genome browser
AA seq
1793 aa
AA seq
DB search
MLKLLSKKKGPSQCPLCKNNITKRSLRESTRFNQLVEGLLKTIRAFELDTGFQFSDTQDF
SKWEKRTPEPLKKEAATIQSVGYRNRSKRFRASESENSTLESSLGVQLFDLGIRKGSLKK
QKKCIKNNAVYIKLGSDSSEDSVKNAICNSVEDKELCQTSPQGTRLKVRLKPREKVEYEL
SEKAIKSLPQHQSDTENVIKENATEGHSEASRGVSSSDLNMEPWDTDMHASSLLPEITSV
LPNTDSMNIEKAELCDKSKRPGLARSQIRQIESKEKCSAGKTPDAEEPHELNAHHLYERQ
ELEEQPECPKYPRRNPQNCLSGTKLKSSIQKVNDWLSRSNDILASDYSSVKIHEQNAETA
SVLEDGHPDITDGNSSISGKTDLVADSTDGAWLHMSERSCPKQAESNNIEDKIFGKTYHR
KSVHTNLNYVTENLVVGAVASDSLIPSEPVKKTRLKRKRKTISGLQPEDFIKKTHTEFIH
KSSEKKIHAVDQILEQEQNGQVMNTVNGHPEQKALVDGHVEEVKDALASELLSVEKESTF
RTGTDSTAGSTNYGGLKLNGRDAKMTKKDKLRKKPSARIVCELELVVDKNPSSSNETELQ
IDSYPSSEEIRKENNSEQKQIRRSRRLQLLSEEIAMATNKAYEPDEQAEKSCVNEVFPDL
KMGNTPVCATTVSLTTDSDQMLASCSVTEEGNEKSLEAIQSSRDQEDLAVSGGEGSQGQR
AKGNLEILEVPDTDWDTQDSTSLFTANTPQNSKAGPSPHRSQCEVMETPKELLDGCSSEN
TGSTTEDLRSLIRQGVKNASETTTEIEDSELDTQYLQNTFRRSKRQTFALGSSPRRECMK
PCVISQALCQPDLDNATDYGGQEKEKLGKRESNKPVQAKSAVMSLAAVCQTEERKPSDCA
SVSRLCHIEPLYGGNDCEFIAGNNQEISQVPNQKQSVSLTGSSASKIIYTKNLLEERLDE
QATSPETAMGNESLAQSSLSPVSPNNSRDNISKVADLNRFIGIGSSGEGSQVEKHKTKKS
ELNTLPKLKLVQPQVCQQSFPQDNFSKEPEREEKEDNVKLAQAISADSSPCFEQTKENTH
FTQVWSETPDLLDSDGEIKENTSFAESDIKEQSAVFGKNGKSSQVRKSRKNLSPLVHRNP
SLSWKSRRQARKLESSEEEASSEEGELPSFQDLIFGKAASTPSQPTKNKNTAKELSANEA
EENLAFLNRDSMSASNLQIPSGEASLDHDSSQESECSGSLFSSHSNSLEDLAGKANDKDS
ALVFGTSHPRTQEVQSGSEMPKVFQDKEERETDLDEDHHPKDQSMDSNLGESGSGYDSET
SHPGDISQLSFQSDILTTQQRDTMQDNLKKLQQEMAVLEAVLEQHGSQVASNSDSQDPGP
CPSMDQPDLKQTNSERGAEENVDHHKSQNMQIFSADKSQAFPGDSRSKNEEARVGGSSLS
KSQMPNRGWNPLGRSRIPREGDSPSKESGRVAAGKEEHKRQPKEQGVRKQNLETNSEPES
GIKVNPKNIKSNPRQNKEPALRDILNLPTSTSALRSCQLQTIEATNTTAPDAPTCNVRGQ
LKEDSASERVKKGGTGHRKITLVSSGLTPKEHMLVQKFARKTHSIVSHQITEGTTHVIMK
TDAEFVCERTLKYFLGIAGGKWVVSFLWVVQSFKEGKMLPEYDFEVRGDVINGRNHRGPE
RARESQGMKIFKGLEICCYGPFTDMSTDQLEWMVKLCGASVVKKPSSLRFRVGSFPVVVV
QPDAWEDDSSFQEIGLICEAPVVTREWVLDSVACYQRQELDTYLISQTSPSLC
NT seq
5382 nt
NT seq
+upstream
nt +downstream
nt
atgttgaagcttctcagcaagaagaaagggccctctcaatgtccactgtgcaagaataat
ataaccaaaagaagccttcgagaaagtacaagatttaatcagctggtggaaggactgctg
aaaaccattcgtgcttttgagcttgacacgggattccaattttcagatactcaggatttt
tcaaaatgggagaagaggactcctgagcctctaaagaaggaagctgctaccattcaaagt
gtgggctacagaaaccgctcaaaaagattcagagccagtgaatcagaaaattcaaccttg
gaatccagtcttggcgtccagctctttgaccttggcatcagaaaaggttccctgaagaag
caaaagaaatgcattaaaaataatgctgtctacatcaagttaggatctgattcttctgaa
gatagtgtgaaaaatgcaatctgtaacagtgttgaagacaaagaattgtgccagacctca
ccacaaggaaccagacttaaagtcagattaaagcccagggaaaaggttgaatatgagtta
tctgagaaggccataaagagcctaccacagcaccaatctgacactgaaaatgtcatcaag
gagaatgccactgaggggcattcagaggcgtctcggggtgtttcttcctcagacttgaat
atggagccatgggacacagacatgcatgccagctcattactacctgagatcaccagtgta
ttgcctaacacagacagcatgaacatagaaaaggctgaactctgtgataaaagcaaaagg
cctggtttagcaaggagccagatcaggcagattgagagtaaggaaaaatgtagtgctggg
aagaccccagatgcagaggagccacatgagctgaatgcccatcatctgtatgagaggcaa
gaactagaggagcagccagagtgccccaagtaccccagaagaaatcctcaaaactgcttg
tcaggaaccaaactgaaaagcagtattcagaaagttaatgactggttatccagaagtaat
gacattttagcctctgactactcctctgttaagatccatgaacagaatgcagagacagct
agtgtcttagaagatgggcatccagatattacagatggaaattctagtatttctgggaaa
actgacttggtggctgactctactgatggtgcctggctacatatgtctgaaagaagctgc
cccaagcaggcagagagcaacaatattgaagacaaaatatttgggaaaacctaccataga
aaatcagttcacactaatttgaattatgtaactgaaaacttggttgttggagctgttgct
tctgattctttgatcccttcagagcctgtcaaaaaaaccaggttaaagcgtaagagaaag
accatctctggcctacagcctgaagatttcatcaagaagacacacactgaatttattcac
aaatcctctgaaaagaaaattcatgctgttgaccaaattctagaacaagaacaaaatggc
caagtgatgaacacggttaatggtcatcccgaacagaaagcattagtagatggtcatgta
gaggaagtgaaagatgctctggcatcagaactgctctctgtggagaaagaatccactttc
agaactggaacagactccacagctggcagcacaaactacgggggactcaaattaaatggt
agagatgccaaaatgacaaaaaaggacaagctgaggaagaagccttcagccaggattgtc
tgtgagcttgagctcgtagttgataaaaacccaagctcttctaatgagactgaactacag
atcgatagctatcccagtagtgaagagataaggaaggaaaataattctgaacagaagcaa
atcagacgcagcagaaggcttcagctgctgtcagaagaaattgcaatggcaaccaacaag
gcctatgagccagatgaacaagcagaaaaaagttgtgtcaatgaagttttcccagatcta
aaaatgggaaatacacctgtctgtgctactactgtcagtctcactactgatagtgatcaa
atgttagctagctgcagtgtcactgaagaaggaaatgaaaagagcctggaagcaatccaa
agcagcagagaccaagaggatctagcagtaagtggaggggaaggatcacaaggccaaaga
gccaaaggaaacctggagatcttggaggttcctgatactgattgggacactcaggacagt
acctcattgtttacagctaatactccacaaaattcaaaagcaggacccagtcctcacaga
agtcaatgtgaagtaatggaaacccccaaggaactcttagatggttgttcatctgaaaac
actggaagcaccacagaagatttgaggagcctgataagacagggagttaaaaatgcctca
gagacaaccacagaaatagaggatagtgaacttgacacccagtatttacagaataccttc
agacgttcaaaacgccagacatttgctctgggttccagtccaagacgggaatgtatgaaa
ccctgtgttatctctcaggctttatgtcagccggatctagataatgccacagattatggg
ggccaggaaaaagaaaaactgggaaaaagagaatccaacaagcccgtgcaagcaaagtct
gcagtcatgagcttagctgcagtttgtcagacagaggagaggaagccaagtgattgtgcc
agtgtctccaggctttgtcacatagaaccattgtatggtggcaatgactgtgaattcatt
gctggaaacaaccaggaaatttcacaagttcctaatcaaaagcaatcagtttctctaaca
ggatcatctgctagtaaaattatatatacaaaaaatctcttggaggaaaggcttgatgaa
caggccacatcccctgaaacagctatgggaaatgaaagcttagcccaaagtagcttaagt
ccagttagcccaaataacagcagagacaatatttctaaagtagctgacttaaacagattt
attggcataggctctagtggagaaggcagtcaagtagaaaaacataaaaccaaaaaatct
gaattaaatacactacctaaattaaagcttgtgcaacctcaagtctgtcaacaaagcttt
cctcaggataactttagcaaagagcctgaaagagaagagaaagaagataatgtaaaatta
gctcaggctattagtgcagattcatctccatgttttgaacaaactaaagagaatacacat
tttactcaggtttggtctgagactcctgacttgttggacagtgatggtgaaattaaagaa
aacactagctttgctgaaagtgatatcaaagaacaatctgctgtttttggcaaaaatggt
aaaagttctcaagtaagaaaatctagaaaaaacctcagccctttagtacatagaaatccc
agtttgagttggaagtcccgaagacaagcccggaaactagagtcctcagaagaagaagcc
tccagtgaggagggagagcttccaagttttcaagacttaatatttggtaaagcagcaagt
acaccttctcagcctaccaaaaataaaaacactgccaaagagctttcagcgaatgaggca
gaagagaatctagccttcctaaacagagatagtatgagtgctagcaatcttcagatacca
tctggggaggcatccctagatcatgattcaagccaagaatctgaatgttctggtagctta
ttttcttcacactctaattcattagaagacttagctgggaaagcaaatgacaaggattct
gctttggtgtttggaacaagtcatcccagaacccaagaagtccagagtgggagtgaaatg
cccaaggttttccaagataaggaagaaagggaaactgacctagatgaagaccatcaccct
aaggaccagagcatggattcaaatttaggtgaatctgggtctgggtatgacagtgaaaca
agccatcctggagacatttcacagctctcgtttcagagtgatattttaaccactcagcaa
agggataccatgcaagacaacctgaaaaaactccaacaggaaatggctgtcctagaggct
gtcttggagcaacacggtagtcaagttgccagcaactctgattctcaggatcctgggccg
tgcccttccatggaccagccagacttgaaacagaccaattcagaaagaggagcagaggaa
aatgttgaccatcacaaaagtcaaaatatgcagatcttttcagcagacaaatcccaagca
tttccaggtgattccagaagcaaaaatgaagaagcaagagttggaggatcttctctttcc
aagtcccaaatgccgaataggggttggaacccactcggccgctccaggattcctcgggaa
ggagactccccttctaaagagagtggtagggtggctgccggaaaggaagaacacaagcgg
caacccaaggaacagggtgtgcggaagcaaaacctagaaacaaactctgagccagaatct
ggaatcaaagtaaaccctaagaacatcaaatccaatccacgtcaaaataaggaacctgcc
ctaagagatatcctcaacctgcccacctcaacttctgcactgaggtcatgccagcttcag
accatagaagctaccaacaccactgctcctgatgcccccacttgcaatgtgaggggccag
ctgaaggaggattctgcctcagagagggttaaaaaaggagggacaggccaccgaaagata
acccttgtgtcatcgggtttgactcccaaagaacatatgctagtgcagaagtttgccagg
aaaacccacagcattgtatctcatcaaattactgaagggaccactcatgtcataatgaaa
acagatgctgagtttgtgtgtgagcggaccctgaagtacttcttgggcattgcaggaggg
aaatgggtagtcagttttctgtgggtggtgcaatcttttaaagaaggaaagatgctgcct
gagtatgactttgaagtcagaggagatgtcatcaatgggagaaatcaccgaggcccagaa
agagcaagagaatctcaggggatgaagatcttcaagggcctggaaatctgttgctatgga
ccatttacagacatgtcaacagatcagttggagtggatggtgaagctgtgtggggcctcg
gtagtgaagaaaccttcctctttgaggttcagagtgggttcttttccagtcgtggttgtg
cagcctgatgcctgggaagatgacagcagttttcaggaaatcgggctgatttgtgaagcg
cctgtagtgacccgggagtgggtgctggacagtgttgcctgttatcagcgccaggagctg
gacacctacttgatatcccagacctccccgagcctctgctga
DBGET
integrated database retrieval system
