Gracilinanus agilis (agile gracile opossum): 123253748
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Entry
123253748 CDS
T07702
Name
(RefSeq) insulin receptor substrate 2-B-like
KO
K07187
insulin receptor substrate 2
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas04022
cGMP-PKG signaling pathway
gas04068
FoxO signaling pathway
gas04081
Hormone signaling
gas04140
Autophagy - animal
gas04152
AMPK signaling pathway
gas04211
Longevity regulating pathway
gas04213
Longevity regulating pathway - multiple species
gas04910
Insulin signaling pathway
gas04920
Adipocytokine signaling pathway
gas04923
Regulation of lipolysis in adipocytes
gas04930
Type II diabetes mellitus
gas04931
Insulin resistance
gas04932
Non-alcoholic fatty liver disease
gas04935
Growth hormone synthesis, secretion and action
gas05010
Alzheimer disease
gas05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
123253748
04022 cGMP-PKG signaling pathway
123253748
04152 AMPK signaling pathway
123253748
09133 Signaling molecules and interaction
04081 Hormone signaling
123253748
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
123253748
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123253748
04923 Regulation of lipolysis in adipocytes
123253748
04920 Adipocytokine signaling pathway
123253748
04935 Growth hormone synthesis, secretion and action
123253748
09149 Aging
04211 Longevity regulating pathway
123253748
04213 Longevity regulating pathway - multiple species
123253748
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
123253748
09164 Neurodegenerative disease
05010 Alzheimer disease
123253748
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
123253748
04932 Non-alcoholic fatty liver disease
123253748
04931 Insulin resistance
123253748
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Gene cluster
GFIT
Motif
Pfam:
IRS
Motif
Other DBs
NCBI-GeneID:
123253748
NCBI-ProteinID:
XP_044538827
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Position
X:70000646..70009606
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AA seq
939 aa
AA seq
DB search
MPEWSLLLTWRVCWVPEGTGSSGAAVVMVAAAPVPGIEKWALKARVAVGEVVDDDRAFRE
VWQVHVKPKGLGQSKNMSGIYRLCLSSKEVHLVRLNAEAPTVQLQLLSIRRCGHSEHFFF
LEVGRSSSIGPGEIWMQVDDSVVAQHMHETFLETMKALKAFADFRPRSKSHSSCTNPISF
LSTRRHLGYLQPCLGMSRRSRTDSMASSPPSCKGSTYRFRTSSEGEGTMDRPFRTVTGSL
MQLNPGRMNPARPESGRYVRAAFNGCCHSRSTSLPVSPFPSGSSPAPETSSRPSSSMCGT
PGDGSGVSSADYGPSSGGMRYFRVRNGTPDSVGNTPPIREERAFTKYVATNKQRAKESAS
GGHREPEKCCKKKTFSLARPPAVTTQQKTTQTSASDLEPAGTPRLLLCSSESVRSRETPK
LEHGENGSSRKQGRNHKAEDEGYMAMMPGVAGSLKSNSDYLPMAPKGASASKRPSSSQKD
SRGYMMMFPRASSVSPGRNSRGAFSKGASNKDEDNEYMDMSPGQPLAPRQSPEGSSLHPP
SFSKSLSSLFSLPKSFRTITEHSDDSDYVPMASPGRLLSTVSEKGRSGNLPPRDIPKAPP
TSRAPDGGFPPKKASRPTKLPLGTRGSSVPRVYPRGTGGESPAEYMNMDFSRKASSAARS
LSAECSPSSFGSCSDHPQSPFNDYMSFATDGNSPKAAKEFANTLKLSGSNPPPRNQLTLD
CARRPLGAAARIRTPTNDADDDYTEMNFNPALSTTTVPSAARSHERVHLDSPSSAVNRLR
IVDEFPEDGTFSLRGPRPEPVVIPRAVRAEPQGRRRHSSETFSRARAAATPSSLFLESEG
LTSASSDSIWSRAGDGAPDSEQGRMSRVTSAGFQNGLNFIATDGRDAAARAAPGRRGASS
GAPNSQRGNGASDLDSGTYVTIDFSRDDIFRCTSSRKGR
NT seq
2820 nt
NT seq
+upstream
nt +downstream
nt
atgccggagtggagcttgctcttgacatggcgggtgtgctgggtacctgaaggtactggc
agcagtggggcagcagtggtgatggtagcagcggcaccagtaccagggatagaaaagtgg
gctttgaaagccagagtcgctgtgggtgaggtggtagacgacgacagagccttcagggag
gtgtggcaggtgcatgtgaaacccaaggggctgggccagagcaagaacatgagcggcatc
tatcgcctgtgcctgtccagcaaagaggtgcacctggtgcgcctgaacgcagaggcgccc
accgtccagctgcagctgctcagcatccgtcgctgcggccactcggagcacttcttcttc
ctcgaggtgggcaggtcatcgtccatcggccccggggagatctggatgcaggtggacgac
tccgtggtggctcagcacatgcacgagaccttcctggaaaccatgaaagccctcaaggcc
tttgccgacttcagacccaggagcaaaagccactcgtcctgcaccaaccccatctcgttc
ctctccaccaggaggcacctgggctacctgcagccctgcctgggtatgtcccgcaggtcc
cgcaccgacagcatggccagctccccgccctcctgcaagggcagcacttaccgattccgc
acctccagcgagggcgagggcaccatggacagacccttccgaacggtcaccggaagcctg
atgcagttgaaccccggccgcatgaacccggcccgcccggaaagtggcaggtacgttcgc
gccgcttttaatggctgctgtcactctcgctctacctccctgccagtgtctcccttcccc
tccgggtccagccccgccccagaaacctcgagcaggccttcgagctccatgtgtggcacc
ccgggtgacggcagcggtgtctcctccgctgattacggccccagctcgggaggcatgagg
tatttccgagtgcgaaacgggaccccggactccgtgggaaacaccccacccatccgagaa
gaacgcgccttcactaagtacgtggcgacgaacaaacagcgcgccaaagaaagtgccagc
ggcggtcatagggaacctgaaaagtgctgtaagaaaaaaactttctccctggccaggcca
ccggctgtaaccacgcaacaaaaaacaacacagacctccgcttcggacctcgagccggct
ggaacccccaggctgctgctctgctcctccgagtcggtgcgatcgagagagacccccaag
ctggagcatggtgagaacgggtccagtcggaagcagggcagaaaccacaaagctgaggat
gaaggctacatggccatgatgccaggagtggccggctctctcaagagcaacagcgattac
ctgcctatggctcctaaaggtgcttctgcctccaaacgcccctcctcctcgcagaaagac
tcccggggctacatgatgatgtttcccagagccagcagcgtctcgccgggccgaaattct
cgtggcgccttctccaagggggcgagtaataaggacgaagataacgaatacatggatatg
tcccccgggcagcccctggcgcccaggcagtctcccgaaggcagttctctgcaccccccc
tccttttccaaaagtttgagctcgctcttctccctgccaaaaagtttccggacgataacc
gaacacagcgacgacagcgactacgtcccgatggcatcacctggaagactgctgagcacc
gtctcggaaaagggccgaagcggaaacttgccccctcgggacattcccaaagcgcctcca
acttcaagagctccggacgggggattcccgccgaagaaggcttcgagacctaccaaactc
cctctgggcacaagaggaagcagcgttccgagagtctatccgcgcggcaccggaggggag
agccctgcggagtacatgaacatggacttcagcaggaaagcaagcagtgcagcccgctcc
ctctcggccgagtgctcgccctcttcattcggctcctgcagtgaccacccgcagtcaccc
tttaacgattacatgagttttgccactgatggtaactcgcccaaagctgccaaggagttc
gccaataccttaaagctgtcaggctccaacccgccgccgcgaaaccagctaactctggac
tgtgctagacgtccccttggtgctgctgcccgcatccgtaccccaactaacgacgcggat
gacgattacaccgaaatgaatttcaacccagcgctgtccacaacaaccgtgccttctgct
gcccggagccacgagcgggtccacctcgacagcccttcctccgctgtaaatcgcctccgc
attgtcgacgaattccccgaggacggcactttctccctccgcggccccaggccggagccc
gttgtaattcccagggcggtgcgagccgagccgcagggcagaagacgccacagttcggaa
actttctctcgcgcccgagccgcggccacaccttcctccctcttcttggagagcgaaggg
ctgacctcggcctcctctgacagcatctggtcccgggccggcgacggtgctcccgattcc
gagcaggggaggatgtcgcgcgtcacctcggctggctttcagaatggcctcaacttcatc
gccaccgacggccgcgatgccgccgcccgcgctgctcccggccgaagaggggccagctcc
ggcgctccgaattcccagcgggggaatggtgcttccgatttggacagtggcacttacgtg
accatcgacttctcccgagatgacatcttcaggtgtacgtcttcgagaaaaggtcggtaa
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