Gavialis gangeticus (Gharial): 109304596
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Entry
109304596 CDS
T07453
Symbol
HSD3B1
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 isoform X1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
ggn
Gavialis gangeticus (Gharial)
Pathway
ggn00140
Steroid hormone biosynthesis
ggn01100
Metabolic pathways
Module
ggn_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
ggn_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ggn00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
109304596 (HSD3B1)
Enzymes [BR:
ggn01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
109304596 (HSD3B1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
109304596 (HSD3B1)
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Paralog
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
KR
NmrA
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
109304596
NCBI-ProteinID:
XP_019382831
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All DBs
Position
Unknown
AA seq
377 aa
AA seq
DB search
MSLAGMTCLVTGAGGFLGQRIVHLLLEEEEALAEIRLLDKVFSSETLLNFARHRGKAEVK
ILEGDIRDAAFLHRACQGVSLIIHTASIIDILGHVEKQLLWEVNVTGTQLLLEACVHSNV
QYFIYTSSIEVTGPNCRGDPICNGDEETAYETSQTFPYAQTKRQAEKHVLEADGQALKAG
GILLTCALRSMYIFGEGSQFLQNHLDQSLLNKNIHPRTSRKEALVNPVYVGNIAWAHIQI
AKALKDPEKAKQIRGQFYYISDDTPPMSYADLDYELTKDLGFGIEPQLPMPLVMLYYFAL
LLESLSFLFRPFFRYIPSTNRHLVNLMNTQFTFSYKKAQRDFGYVPRYTWDEAKQHTGQW
IASLIPQRRVYLKNKTA
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgtctttggctggaatgacctgtctggtcacgggagcagggggatttcttggccagaga
attgtccatttactgctggaggaggaggaggcactggctgagatccgacttctggacaaa
gtctttagctctgagacactcctgaactttgcaaggcacaggggtaaggctgaggtgaaa
atcctggagggggacatccgagatgctgccttcttgcatcgcgcgtgccagggcgtttcc
ctgatcatccacacagcttccatcattgatatcttgggtcatgtagaaaagcagctgctc
tgggaagtcaatgttacaggtactcagctactgctggaggcgtgtgtccacagtaacgtc
caatacttcatttataccagctccatagaagtgacaggcccaaactgcagaggtgatccc
atctgcaatggtgatgaagaaacagcctatgagacttcacaaacatttccatatgcccag
acaaagagacaagcagagaaacatgtcctggaggcagatggtcaggcactaaaggcaggt
ggcatcctgctgacgtgcgccctacggtctatgtacatctttggagaaggaagtcaattt
ctccagaatcacctggatcaaagcctcttgaacaaaaatatccacccgcgtacttccagg
aaagaagctttagtgaatcctgtatatgtgggaaacattgcctgggctcacattcaaatc
gccaaagccctgaaggatccagaaaaagctaaacagatcagagggcaattttactatatt
tcagatgacactccccccatgagctatgcagacctagattatgagctgacaaaggacctg
ggctttgggattgagccccagctgcccatgccactggtaatgctgtactattttgcattg
ctactggagagcttgagtttcttgttcaggccctttttcagatacatcccctctaccaac
cgtcaccttgtgaatctgatgaacacacagtttaccttctcctacaagaaagcacagagg
gattttggctatgtaccccgctacacatgggatgaggctaagcagcacactggtcagtgg
attgcctcactgattccacagaggagagtgtacctgaaaaataaaactgcctga
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