KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101132059
Entry
101132059         CDS       T02442                                 
Symbol
PDGFA
Name
(RefSeq) platelet-derived growth factor subunit A isoform X1
  KO
K04359  platelet-derived growth factor subunit A
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo01521  EGFR tyrosine kinase inhibitor resistance
ggo04010  MAPK signaling pathway
ggo04014  Ras signaling pathway
ggo04015  Rap1 signaling pathway
ggo04020  Calcium signaling pathway
ggo04072  Phospholipase D signaling pathway
ggo04151  PI3K-Akt signaling pathway
ggo04510  Focal adhesion
ggo04540  Gap junction
ggo04630  JAK-STAT signaling pathway
ggo04810  Regulation of actin cytoskeleton
ggo05200  Pathways in cancer
ggo05202  Transcriptional misregulation in cancer
ggo05206  MicroRNAs in cancer
ggo05214  Glioma
ggo05215  Prostate cancer
ggo05218  Melanoma
ggo05231  Choline metabolism in cancer
ggo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101132059 (PDGFA)
   04014 Ras signaling pathway
    101132059 (PDGFA)
   04015 Rap1 signaling pathway
    101132059 (PDGFA)
   04630 JAK-STAT signaling pathway
    101132059 (PDGFA)
   04020 Calcium signaling pathway
    101132059 (PDGFA)
   04072 Phospholipase D signaling pathway
    101132059 (PDGFA)
   04151 PI3K-Akt signaling pathway
    101132059 (PDGFA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101132059 (PDGFA)
   04540 Gap junction
    101132059 (PDGFA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101132059 (PDGFA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101132059 (PDGFA)
   05202 Transcriptional misregulation in cancer
    101132059 (PDGFA)
   05206 MicroRNAs in cancer
    101132059 (PDGFA)
   05231 Choline metabolism in cancer
    101132059 (PDGFA)
  09162 Cancer: specific types
   05214 Glioma
    101132059 (PDGFA)
   05218 Melanoma
    101132059 (PDGFA)
   05215 Prostate cancer
    101132059 (PDGFA)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101132059 (PDGFA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101132059 (PDGFA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ggo04052]
    101132059 (PDGFA)
   00536 Glycosaminoglycan binding proteins [BR:ggo00536]
    101132059 (PDGFA)
Cytokines and neuropeptides [BR:ggo04052]
 Cytokines
  Growth factors (RTK binding)
   101132059 (PDGFA)
Glycosaminoglycan binding proteins [BR:ggo00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   101132059 (PDGFA)
SSDB
Motif
Pfam: PDGF PDGF_N
Other DBs
NCBI-GeneID: 101132059
NCBI-ProteinID: XP_030869280
LinkDB
Position
6:complement(join(7953790..7953999,7963447..7963634,7964856..7964960,7969942..7970034,7972903..7973164))
AA seq 285 aa
MREAQNPGDPHRWLLSPPSPRLPSSGRGPAFGAGVGDWGARGPRVGTRRAAGPSPDWSSL
PSGNVGGGSSFRCPRLRILGGGAWQPPGSRDPPRGDREAGPQSDPQHPGPPATPGDRLRS
EDSLDTSLRVHGVHATKHAPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSA
NFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHL
ECACATTSLNPDYREEDTGEWLPSSASVLENRSSEPCFWGVRWPP
NT seq 858 nt   +upstreamnt  +downstreamnt
atgcgggaggctcagaacccgggggaccctcaccggtggctcctttcccctccatcccct
cgacttcccagctcagggcgcggccctgccttcggcgcgggagtgggggactggggggcg
cggggtcccagggtggggacgaggcgggctgcaggcccttcccccgactggagctcgctc
ccaagtggaaatgtgggtggagggtcctcattcagatgccccaggcttcggatcctgggc
gggggcgcgtggcagccgccaggaagccgagatcccccgcgaggtgatcgagaggctggc
ccgcagtcagatccacagcatccgggacctccagcgactcctggagatagactccggagt
gaggattctttggataccagcctgagagttcacggggtccacgccactaagcatgcgccc
gagaagcggcccctgcccattcgaaggaagagaagcatcgaggaagctgtccccgctgtc
tgcaagaccaggacggtcatttacgagattcctcggagtcaggtcgaccccacatccgcc
aacttcctgatctggcccccgtgtgtggaggtgaaacgctgcactggctgctgcaacacg
agcagtgtcaagtgccagccctcccgcgtccaccaccgcagcgtcaaggtggccaaggtg
gaatacgtcaggaagaagccaaaattaaaagaagtccaggtgaggttagaggagcatttg
gagtgcgcctgcgcgaccaccagcctgaatccggattatcgggaagaggacacgggtgag
tggctgccttcatcggcatcggtgttggagaacaggtcttcagagccttgcttttggggt
gttaggtggcccccttga

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