KEGG T02442: 101132108

Gorilla gorilla gorilla (western lowland gorilla): 101132108

Entry

101132108         CDS       T02442

Symbol

TPH1

Name

(RefSeq) tryptophan 5-hydroxylase 1

K00502

tryptophan 5-monooxygenase [EC:1.14.16.4]

Organism

ggo Gorilla gorilla gorilla (western lowland gorilla)

Pathway

ggo00380

Tryptophan metabolism

ggo00790

Folate biosynthesis

ggo01100

Metabolic pathways

ggo04726

Serotonergic synapse

Module

ggo_M00037

Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin

Brite

KEGG Orthology (KO) [BR:ggo00001]
09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    101132108 (TPH1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    101132108 (TPH1)
09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    101132108 (TPH1)
Enzymes [BR:ggo01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     101132108 (TPH1)

SSDB

Motif

Pfam:

Biopterin_H ACT TH_ACT ACT_4 zf-C2HE

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

9:complement(join(24403871..24404045,24405677..24405810,24406767..24406862,24408465..24408591,24409374..24409509,24412039..24412235,24412386..24412453,24416136..24416236,24418807..24418990,24423471..24423587))

AA seq 444 aa
MIEDNKENKDNSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEF
EIFVDCDINREQLNDIFHLLKSHTNVLSVNPPDNFTLKEDGMETVPWFPKKISDLDHCAN
RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDLIPKVEFTEEEIKTWGTVFQE
LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD
FLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA
SEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITC
KQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSA
MNELQHDLDVVSDALAKVSRKPSI

NT seq 1335 nt +upstreamnt +downstreamnt
atgattgaagacaataaggagaacaaagacaattccttagaaaggggaagagcaagtctc
attttttccttaaagaatgaagttggaggacttataaaagccctgaaaatctttcaggag
aagcatgtgaatctgttacatatcgagtcccgaaaatcaaaaagaagaaactcagaattt
gagatttttgttgactgtgacatcaacagagaacaattgaatgatattttccatctgctg
aagtctcataccaatgttctctctgtgaatccaccagataattttactttgaaggaagat
ggtatggaaactgttccttggtttccaaagaagatttctgacctggaccattgtgccaac
agggttctgatgtatggatctgaactagatgcagaccatcctggcttcaaagacaatgtc
taccgtaaacgtcgaaagtattttgcggacttggctatgaattataaacatggagacctc
attccaaaggttgaattcactgaagaggagattaagacctggggaaccgtattccaagag
ctcaacaaactctacccaacccatgcttgcagagagtatctcaaaaacttacctttgctt
tctaaatattgtgggtatcgggaggataatatcccacaattggaagatgtctccaacttt
ttaaaagagcgtacaggtttttccatccgtcctgtggctggttacttatcaccaagagat
ttcttatcaggtttagcctttcgagtttttcactgcactcaatatgtgagacacagttca
gatcccttctataccccagagccagatacctgccatgaactcttaggtcatgtcccgctt
ttggctgaacctagttttgcccaattctcccaagaaattggcttggcttctcttggcgct
tcagaggaggctgttcaaaaactggcaacgtgctactttttcactgtggagtttggtcta
tgtaaacaagatggacagctaagagtctttggtgctggcttactttcttctatcagtgaa
ctcaaacatgcactttctggacatgccaaagtaaagccctttgatcccaagattacctgc
aaacaggaatgtcttatcacaacttttcaagatgtctactttgtatctgaaagttttgaa
gatgcaaaggagaagatgagagaatttaccaaaacaattaagcgtccatttggagtgaag
tataatccatatacacggagtattcagatcctgaaagacaccaagagcataaccagtgcc
atgaacgagctgcagcatgatctcgatgttgtcagtgatgcccttgctaaggtcagcagg
aagccgagtatctaa

DBGET integrated database retrieval system