KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101135722
Entry
101135722         CDS       T02442                                 
Symbol
APAF1
Name
(RefSeq) apoptotic protease-activating factor 1 isoform X1
  KO
K02084  apoptotic protease-activating factor
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo01524  Platinum drug resistance
ggo04115  p53 signaling pathway
ggo04210  Apoptosis
ggo04215  Apoptosis - multiple species
ggo05010  Alzheimer disease
ggo05012  Parkinson disease
ggo05014  Amyotrophic lateral sclerosis
ggo05016  Huntington disease
ggo05020  Prion disease
ggo05022  Pathways of neurodegeneration - multiple diseases
ggo05134  Legionellosis
ggo05152  Tuberculosis
ggo05160  Hepatitis C
ggo05161  Hepatitis B
ggo05162  Measles
ggo05164  Influenza A
ggo05168  Herpes simplex virus 1 infection
ggo05169  Epstein-Barr virus infection
ggo05200  Pathways in cancer
ggo05222  Small cell lung cancer
ggo05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    101135722 (APAF1)
   04215 Apoptosis - multiple species
    101135722 (APAF1)
   04115 p53 signaling pathway
    101135722 (APAF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101135722 (APAF1)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    101135722 (APAF1)
  09172 Infectious disease: viral
   05161 Hepatitis B
    101135722 (APAF1)
   05160 Hepatitis C
    101135722 (APAF1)
   05164 Influenza A
    101135722 (APAF1)
   05162 Measles
    101135722 (APAF1)
   05168 Herpes simplex virus 1 infection
    101135722 (APAF1)
   05169 Epstein-Barr virus infection
    101135722 (APAF1)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    101135722 (APAF1)
   05152 Tuberculosis
    101135722 (APAF1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101135722 (APAF1)
   05012 Parkinson disease
    101135722 (APAF1)
   05014 Amyotrophic lateral sclerosis
    101135722 (APAF1)
   05016 Huntington disease
    101135722 (APAF1)
   05020 Prion disease
    101135722 (APAF1)
   05022 Pathways of neurodegeneration - multiple diseases
    101135722 (APAF1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101135722 (APAF1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101135722 (APAF1)
SSDB
Motif
Pfam: Beta-prop_WDR3_1st Beta-prop_WDR5 Beta-prop_THOC3 WD40 WD40_Prp19 WD40_WDHD1_1st APAF1_C WD40_CDC20-Fz Beta-prop_WDR3_2nd Beta-prop_EML_2 EIF3I Beta-prop_TEP1_2nd NB-ARC WDR55 Beta-prop_WDR36-Utp21_2nd WD40_Gbeta WHD_APAF1 WD40_MABP1-WDR62_2nd Beta-prop_CAF1B_HIR1 Beta-prop_WDR36-Utp21_1st Beta-prop_WDR90_POC16_2nd ANAPC4_WD40 Beta-prop_EML Beta-prop_WDR75_1st WDR90_beta-prop_4th CARD Beta-prop_IFT122_1st Beta-prop_RIG_2nd NBCH_WD40 Beta-prop_EIPR1 Beta-prop_WDR41 Beta-prop_TEP1_C Beta-prop_VPS8 Beta-prop_WDR19_1st WD40_MABP1-WDR62_1st Beta-prop_Vps41 Beta-prop_Aladin RMC1_N eIF2A Beta-prop_SCAP Beta-prop_HPS5 Beta-prop_WDR35_TULP_N Beta-prop_IFT140_1st WD40_like Beta-prop_NUP159_NUP214 WD40_RFWD3 CARD_2 Beta-prop_WDR11_2nd Beta-prop_DCAF4 Ge1_WD40 Beta-prop_ACSF4 Beta-prop_Nup120_160 Utp8_b_propeller AAA_16 Beta-prop_RSE1_2nd NPHP3_N AAA_22 Hira Beta-prop_SPT8 DUF2677 AAA_18 nSTAND6 NACHT
Other DBs
NCBI-GeneID: 101135722
NCBI-ProteinID: XP_018894404
Ensembl: ENSGGOG00000008401
UniProt: A0A2I2YKE3
LinkDB
Position
10:join(114072935..114073072,114073201..114073390,114074061..114074258,114083015..114083198,114086297..114086409,114086516..114086647,114089356..114089594,114089993..114090160,114091322..114091453,114094790..114094903,114095369..114095553,114101208..114101334,114104065..114104190,114106930..114107061,114110575..114110700,114123213..114123374,114127175..114127303,114130282..114130407,114132372..114132491,114136116..114136232,114139229..114139354,114147015..114147134,114147461..114147586,114149238..114149363,114150997..114151140,114156233..114156379)
AA seq 1248 aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMI
LKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVP
QRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
ILDDVWDSWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYD
YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDC
MYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAV
SENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINK
KNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEVKAHEDEV
LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS
SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDVTSANERKS
INVKQFFLNSEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHH
STIQYCDFSPQNHLAVVALSQYCVELWNIDSRSKVADCRGHLSWVHGVMFSPDGSSFLTS
SDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGKTGQIDYLT
EAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS
SSDDSEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKD
FVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDST
LLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLLSAGGYIK
WWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
NT seq 3747 nt   +upstreamnt  +downstreamnt
atggatgcaaaagctcgaaattgtttgcttcaacatagagaagctctggaaaaggacatc
aagacatcctacatcatggatcacatgattagtgatggatttttaacaatatcagaagag
gaaaaagtaagaaatgagcccactcaacagcaaagagcggctatgctaattaaaatgata
cttaaaaaagataatgattcctacgtatcattctacaatgctctactacatgaaggatat
aaagatcttgctgcccttctccatgatggcattcctgttgtctcttcttccagtggtaaa
gattcagttagtggaataacttcgtatgtaaggacagtcctgtgtgaaggtggagtacca
cagaggccagttgtttttgtcacaaggaagaagctggtgaatgcaattcagcagaagctc
tccaaattgaaaggtgaaccaggatgggtcaccatacatggaatggcaggctgtgggaag
tctgtattagctgcagaagctgttagagatcattcccttttagaaggttgtttcccaggg
ggagtgcattgggtttcagttgggaaacaagacaaatctgggcttctgatgaaactgcag
aatctttgcacacggttggatcaggatgagagtttttcccagaggcttccacttaatatt
gaagaggctaaagaccgtctccgcattctgatgcttcgcaaacacccaaggtctctgttg
atcttggatgatgtttgggactcttgggtgttgaaagcttttgacaatcagtgtcagatt
cttcttacaaccagagacaagagtgttacagattcagtaatgggtcctaaatatgtagtc
cctgtggagagttccttaggaaaggaaaaaggacttgaaattttatccctttttgttaat
atgaagaaggcagatttgccagaacaagctcatagtattataaaagaatgtaaaggctct
ccccttgtagtatctttaattggtgcacttttacgtgattttcccaatcgctgggagtac
tacctcaaacagcttcagaataagcagtttaagagaataaggaaatcttcgtcttatgat
tatgaggctctagatgaagccatgtctataagtgttgaaatgctcagagaagacatcaaa
gattattacacagatctttccatccttcagaaggacgttaaggtgcctacaaaggtgtta
tgtattctctgggacatggaaactgaagaagttgaagacatactgcaggagtttgtaaat
aagtctcttttattctgtgatcggaatggaaagtcgtttcgttattatttacatgatctt
caagtagattttcttacagagaagaattgcagccagcttcaggatctacataagaagata
atcactcagtttcagagatatcaccagccgcatactctttcaccagatcaggaagactgt
atgtattggtacaactttctggcctatcacatggccagcgccaagatgcacaaggaactt
tgtgctttaatgttttccctggattggattaaagcaaaaacagaacttgtaggccctgct
catctgattcatgaatttgtggaatacagacatatactagatgaaaaggattgtgcagtc
agtgagaattttcaggagtttttatctttaaatggacaccttcttggacgacagccattt
cctaatattgtacaactgggtctctgtgagccggaaacttcagaagtttatcagcaagct
aagctgcaggccaagcaggaggtcgataatggaatgctttacctggaatggataaacaaa
aaaaacatcacgaatctttcccgcttagttgtccgcccccacacagatgctgtttaccat
gcctgcttttctgaggatggtcagagaatagcttcttgtggagctgataaaaccttacag
gtgttcaaagctgaaacaggagagaaacttttagaagtcaaggctcatgaggatgaagtg
ctttgttgtgcattctctacagatgacagatttatagcaacctgctcagtggataaaaaa
gtgaagatttggaattctatgaccggggaactagtacacacctatgatgagcactcagag
caagtcaattgctgccatttcaccaacagtagtcatcatcttctcttagccactgggtca
agtgactgcttcctcaaactttgggatttgaatcaaaaagaatgtcgaaataccatgttt
ggtcatacaaattcagtcaatcactgcagattttcaccagatgataagcttttggctagt
tgttcagctgatggaaccttaaagctttgggatgtgacatcagcaaatgagaggaaaagc
attaatgtgaaacagttcttcctaaattcggaggaccctcaagaggatatggaagtgata
gtgaagtgttgttcgtggtctgctgatggtgcaaggataatggtggcagcaaaaaataaa
atctttctttttgacattcataccagtggcctattgggagaaatccacacgggccatcac
agcaccatccagtactgtgacttctccccacaaaaccatttggcagtggttgctttgtcc
cagtactgtgtagagttgtggaatatagactcacgttcaaaggtggctgattgcagagga
catttaagttgggttcatggtgtgatgttttcccctgatggatcatcatttttgacatct
tctgatgaccagacaatcaggctctgggagacaaagaaagtatgtaagaactctgctgta
atgttaaagcaagaagtagatgttgtgtttcaagaaaatgaagtgatggtccttgcagtt
gaccatataagacgtctgcaactcattaatggaaaaacaggtcagattgattatctgact
gaagctcaagttagctgctgttgcttaagtccacatcttcagtacattgcatttggagat
gaaaatggagccattgagattttagaacttgtaaacaatagaatcttccagtccaggttt
cagcacaagaaaactgtatggcacatccagttcacagccgatgagaagactcttatttca
agttctgatgattctgaaattcaggtatggaattggcaattggacaaatgtatctttcta
cgaggccatcaggaaacagtgaaagactttagactcttgaaaaattcaagactgctttct
tggtcatttgatggaacagtgaaggtatggaatattattactggaaataaagaaaaagac
tttgtctgtcaccagggtacagtactttcttgtgacatttctcacgatgctaccaagttt
tcgtctacctctgctgacaagactgcaaagatctggagttttgatctccttttgccactt
catgaattgaggggccacaacggctgtgtgcgctgctctgccttctctgtggacagtacc
ctgctggcaacgggagatgacaatggagaaatcaggatatggaatgtctcaaacggtgag
cttcttcatttgtgtgctccgctttcagaagaaggagctgctacccatggaggctgggtg
actgacctttgcttttctccagatggcaaaatgcttctctctgctggaggatatattaag
tggtggaacgttgtcactggggaatcctcacagaccttctacacaaatggaaccaatctt
aagaaaatacatgtgtcccctgacttcaaaacatatgtgactgtggataatcttggtatt
ttatatattttacagactttagaataa

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