KEGG T02442: 101138083

Gorilla gorilla gorilla (western lowland gorilla): 101138083

Entry

101138083         CDS       T02442

Symbol

HMGCS1

Name

(RefSeq) hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1

K01641

hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]

Organism

ggo Gorilla gorilla gorilla (western lowland gorilla)

Pathway

ggo00280

Valine, leucine and isoleucine degradation

ggo00650

Butanoate metabolism

ggo00900

Terpenoid backbone biosynthesis

ggo01100

Metabolic pathways

ggo03320

PPAR signaling pathway

Module

ggo_M00095

C5 isoprenoid biosynthesis, mevalonate pathway

Brite

KEGG Orthology (KO) [BR:ggo00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    101138083 (HMGCS1)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    101138083 (HMGCS1)
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    101138083 (HMGCS1)
09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    101138083 (HMGCS1)
Enzymes [BR:ggo01000]
2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.10  hydroxymethylglutaryl-CoA synthase
     101138083 (HMGCS1)

SSDB

Motif

Pfam:

HMG_CoA_synt_C HMG_CoA_synt_N Cullin PS_Dcarbxylase

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

19:join(68611594..68612041,68612425..68612550,68613387..68613551,68614633..68614798,68615631..68615801,68616326..68616432,68618222..68618347,68618558..68618721,68619972..68620061)

AA seq 520 aa
MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCT
DREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDI
EGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALL
IGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKI
RAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEA
FGDVKLEDTYFDRDVEKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQY
SPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAP
DVFTENMKLREDTHHLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARRPTPNDDTLDEG
VGLVHSNIATEHIPSPAKKVPRLPATAAEPEAAVISNGEH

NT seq 1563 nt +upstreamnt +downstreamnt
atgcctggatcacttcctttgaatgcagaagcttgctggccaaaagatgtgggaatcgtt
gcccttgagatctattttccttctcaatatgttgatcaagcagagttggaaaaatatgat
ggtgtagatgctggaaagtataccattggcttgggccaggccaagatgggcttctgcaca
gatagagaagatattaactctctttgcatgactgtggttcagaatcttatggagagaaat
aacctttcctatgattgcattgggcggctggaagttggaacagagacaatcatcgacaaa
tcaaagtctgtgaagactaatttgatgcagctgtttgaagagtctgggaatacagatata
gaaggaatcgacacaactaatgcatgctatggaggcacagctgctgtcttcaatgctgtt
aactggattgaatccagctcttgggatggacggtatgccctggtagttgcaggagatatt
gctgtatatgccacaggaaatgctagacctacaggtggagttggagcagtagctctgcta
attgggccaaatgctcctttaatttttgaacgagggcttcgtgggacacatatgcaacat
gcctatgatttttacaagcctgatatgctatctgaatatcctatagtagatggaaaactc
tccatacagtgctacctcagtgcattagaccgctgctattctgtctactgcaaaaagatc
cgtgcccagtggcagaaagagggaaatgataaagattttaccttgaatgattttggcttc
atgatctttcattcaccatattgtaaactggttcagaaatctctagctcggatgttgctg
aatgacttccttaatgaccagaatagagataaaaatagtatctatagtggcctggaagcc
tttggggatgttaaattagaagacacctactttgatagagatgtggagaaggcatttatg
aaggctagctctgaactcttcagtcagaaaacaaaggcatctttacttgtatcaaatcaa
aatggaaatatgtacacatcttcagtatatggttcccttgcatctgttctagcacagtac
tcacctcagcaattagcagggaagagaattggagtgttttcttatggttctggtttggct
gccactctgtactctcttaaagtcacacaagatgctacaccagggtctgctcttgataaa
ataacagcaagtttatgtgatcttaaatcaaggcttgattcaagaactggtgtggcacca
gatgtcttcactgaaaacatgaagctcagagaggacacccatcatttggtcaactatatt
ccccagggttcaatagattcactctttgaaggaacatggtacttagttagggtggatgaa
aagcacagaagaacttacgctcggcgtcccactccaaatgatgacactttggatgaagga
gtaggacttgtgcattcaaacatagcaactgagcatattccaagccctgccaagaaagta
ccaagactccctgccacagcagcagaacctgaagcagctgtcattagtaatggggaacat
taa

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