KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101141389
Entry
101141389         CDS       T02442                                 
Symbol
ADCY2
Name
(RefSeq) adenylate cyclase type 2 isoform X2
  KO
K08042  adenylate cyclase 2 [EC:4.6.1.1]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00230  Purine metabolism
ggo01100  Metabolic pathways
ggo01522  Endocrine resistance
ggo04015  Rap1 signaling pathway
ggo04020  Calcium signaling pathway
ggo04022  cGMP-PKG signaling pathway
ggo04024  cAMP signaling pathway
ggo04062  Chemokine signaling pathway
ggo04072  Phospholipase D signaling pathway
ggo04081  Hormone signaling
ggo04082  Neuroactive ligand signaling
ggo04114  Oocyte meiosis
ggo04211  Longevity regulating pathway
ggo04213  Longevity regulating pathway - multiple species
ggo04261  Adrenergic signaling in cardiomyocytes
ggo04270  Vascular smooth muscle contraction
ggo04371  Apelin signaling pathway
ggo04540  Gap junction
ggo04611  Platelet activation
ggo04713  Circadian entrainment
ggo04714  Thermogenesis
ggo04723  Retrograde endocannabinoid signaling
ggo04724  Glutamatergic synapse
ggo04725  Cholinergic synapse
ggo04727  GABAergic synapse
ggo04750  Inflammatory mediator regulation of TRP channels
ggo04911  Insulin secretion
ggo04912  GnRH signaling pathway
ggo04913  Ovarian steroidogenesis
ggo04914  Progesterone-mediated oocyte maturation
ggo04915  Estrogen signaling pathway
ggo04916  Melanogenesis
ggo04918  Thyroid hormone synthesis
ggo04921  Oxytocin signaling pathway
ggo04922  Glucagon signaling pathway
ggo04923  Regulation of lipolysis in adipocytes
ggo04925  Aldosterone synthesis and secretion
ggo04926  Relaxin signaling pathway
ggo04927  Cortisol synthesis and secretion
ggo04928  Parathyroid hormone synthesis, secretion and action
ggo04934  Cushing syndrome
ggo04935  Growth hormone synthesis, secretion and action
ggo04970  Salivary secretion
ggo04971  Gastric acid secretion
ggo04972  Pancreatic secretion
ggo04976  Bile secretion
ggo05032  Morphine addiction
ggo05163  Human cytomegalovirus infection
ggo05166  Human T-cell leukemia virus 1 infection
ggo05200  Pathways in cancer
ggo05207  Chemical carcinogenesis - receptor activation
ggo05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    101141389 (ADCY2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101141389 (ADCY2)
   04371 Apelin signaling pathway
    101141389 (ADCY2)
   04020 Calcium signaling pathway
    101141389 (ADCY2)
   04072 Phospholipase D signaling pathway
    101141389 (ADCY2)
   04024 cAMP signaling pathway
    101141389 (ADCY2)
   04022 cGMP-PKG signaling pathway
    101141389 (ADCY2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    101141389 (ADCY2)
   04081 Hormone signaling
    101141389 (ADCY2)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101141389 (ADCY2)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101141389 (ADCY2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101141389 (ADCY2)
   04062 Chemokine signaling pathway
    101141389 (ADCY2)
  09152 Endocrine system
   04911 Insulin secretion
    101141389 (ADCY2)
   04922 Glucagon signaling pathway
    101141389 (ADCY2)
   04923 Regulation of lipolysis in adipocytes
    101141389 (ADCY2)
   04912 GnRH signaling pathway
    101141389 (ADCY2)
   04913 Ovarian steroidogenesis
    101141389 (ADCY2)
   04915 Estrogen signaling pathway
    101141389 (ADCY2)
   04914 Progesterone-mediated oocyte maturation
    101141389 (ADCY2)
   04921 Oxytocin signaling pathway
    101141389 (ADCY2)
   04926 Relaxin signaling pathway
    101141389 (ADCY2)
   04935 Growth hormone synthesis, secretion and action
    101141389 (ADCY2)
   04918 Thyroid hormone synthesis
    101141389 (ADCY2)
   04928 Parathyroid hormone synthesis, secretion and action
    101141389 (ADCY2)
   04916 Melanogenesis
    101141389 (ADCY2)
   04925 Aldosterone synthesis and secretion
    101141389 (ADCY2)
   04927 Cortisol synthesis and secretion
    101141389 (ADCY2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101141389 (ADCY2)
   04270 Vascular smooth muscle contraction
    101141389 (ADCY2)
  09154 Digestive system
   04970 Salivary secretion
    101141389 (ADCY2)
   04971 Gastric acid secretion
    101141389 (ADCY2)
   04972 Pancreatic secretion
    101141389 (ADCY2)
   04976 Bile secretion
    101141389 (ADCY2)
  09156 Nervous system
   04724 Glutamatergic synapse
    101141389 (ADCY2)
   04727 GABAergic synapse
    101141389 (ADCY2)
   04725 Cholinergic synapse
    101141389 (ADCY2)
   04723 Retrograde endocannabinoid signaling
    101141389 (ADCY2)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101141389 (ADCY2)
  09149 Aging
   04211 Longevity regulating pathway
    101141389 (ADCY2)
   04213 Longevity regulating pathway - multiple species
    101141389 (ADCY2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101141389 (ADCY2)
   04714 Thermogenesis
    101141389 (ADCY2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101141389 (ADCY2)
   05207 Chemical carcinogenesis - receptor activation
    101141389 (ADCY2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101141389 (ADCY2)
   05163 Human cytomegalovirus infection
    101141389 (ADCY2)
  09165 Substance dependence
   05032 Morphine addiction
    101141389 (ADCY2)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    101141389 (ADCY2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101141389 (ADCY2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101141389 (ADCY2)
Enzymes [BR:ggo01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     101141389 (ADCY2)
SSDB
Motif
Pfam: Guanylate_cyc Adcy_cons_dom AC_N HNOBA
Other DBs
NCBI-GeneID: 101141389
NCBI-ProteinID: XP_030859316
Ensembl: ENSGGOG00000011188
LinkDB
Position
19:complement(join(104272026..104272178,104278252..104278376,104281972..104282086,104294160..104294267,104296528..104296674,104309113..104309271,104314450..104314534,104325803..104325972,104332092..104332211,104341370..104341507,104355220..104355304,104372074..104372171,104374720..104374789,104382077..104382157,104386426..104386469,104389942..104390118,104391488..104391620,104392442..104392600,104400675..104400802,104403185..104403296,104408202..104408350,104473052..104473201,104576561..104576722,104682249..104682446,104700216..104700425))
AA seq 1091 aa
MWQEAMRRRRYLRDRAEEAAGGGDGLPRSRDWLYESYYCMSQQHPLIVFLLLIVMGSCLA
LLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWICLVAM
GYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSAT
PGGKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQ
ERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFT
RLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVK
MGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGG
VPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPR
HTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTL
RTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKVLEKEYRATALPAF
KYYVTCACLIFFCIFIVQILVLPKTSVLGISFGAAFLLLAFILFVCFAGQLLQCSKKASP
LLMWLLKSSGIIANRPWPRISLTIITTAIILMMAVFNMFFLSDSEETIPPTANTTNTSFS
ASNNQVAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTILLHT
HARVLGDYSQVLFERPGIWKDLKTMGSVSLSIFFITLLVLGRQNEYYCRLDFLWKNKFKK
EREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFY
TESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHS
QEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDI
WGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFVNTEM
SRSLSQSNVAS
NT seq 3276 nt   +upstreamnt  +downstreamnt
atgtggcaggaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggaggcggcg
ggcggcggagacgggctgccgcggtcccgggactggctctacgagtcctactactgcatg
agccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggctcctgcctcgcc
ctgctcgccgtcttcttcgcgctcgggctggaagttgaagaccatgtggcgtttctaata
acagttccaactgccctggcgattttctttgcgatatttatcctggtctgcatcgagtct
gtgtttaagaagctgctgcgcctcttctcgttggtgatatggatatgccttgttgccatg
ggatacctgttcatgtgttttggaggcaccgtctctccctgggaccaggtatcattcttc
ctcttcatcatcttcgtggtgtacaccatgctgcccttcaacatgcgagacgccatcatt
gccagcgtcctcacctcctcctcccacaccatcgtgcttagcgtctgcctgtctgcaaca
ccgggaggcaaggagcacctggtctggcagatcctggccaatgtgatcattttcatctgt
gggaacctggcgggagcctaccataagcacctcatggaactcgctcttcagcaaacatat
caggacacctgtaattgcatcaagtcccggatcaagttggaatttgaaaaacgtcaacag
gagcggcttctgctctccctgctgccggcccacatcgccatggagatgaaagcggagatc
atccagaggctgcagggccccaaggcgggccagatggagaacacaaataacttccacaac
ctgtatgtgaagcggcataccaacgtgagcatcttatacgccgacatcgttggctttacc
cggctggcaagtgactgctccccgggagaactagtccacatgctgaatgagctctttgga
aagtttgatcaaattgcaaaggagaatgaatgcatgagaattaaaattttaggagactgc
tactactgtgtatctggactccctatatctctccctaaccatgccaagaactgtgtgaaa
atggggctggacatgtgtgaagccataaagaaagtgagggatgctactggagttgatatc
aacatgcgcgtgggcgtgcattctgggaatgtcctgtgcggcgtgattggtctgcagaag
tggcaatatgatgtgtggtcacatgatgtgaccttggccaaccacatggaagctggaggg
gtccctggacgtgttcacatttcttctgtcaccctggagcacttgaatggcgcttataaa
gtggaggagggagatggtgacattagggacccatatttaaaacagcacctggtgaaaacc
tactttgtgatcaaccccaagggagaacgacggagcccccagcatctcttcagacctcgc
cacacccttgatggagccaaaatgagggcctcggtccgcatgacccggtacttggagtcc
tggggggcagccaagccctttgcacacctacatcacagggacagcatgaccacagagaac
ggcaagatcagcaccacggatgtacccatgggtcagcataattttcaaaatcgcacctta
agaaccaagtcacaaaagaagagatttgaagaagaattgaatgaaaggatgattcaagca
attgatgggattaatgcacagaagcaatggctcaagtctgaagacattcagagaatctca
ctgcttttctataacaaagtactagaaaaagagtaccgggccacggcactgccagcgttc
aagtattatgtgacttgtgcctgtctcatattcttctgcatcttcattgtgcagattctt
gtgctgccaaaaacgtccgtcctgggcatctcctttggggctgcgtttctcttgctggcc
ttcatcctcttcgtctgctttgctggacagcttctgcaatgcagcaaaaaagcctctccc
ctgctcatgtggcttttgaagtcctcgggcatcattgccaaccgcccctggccacggatc
tctctcacgatcatcaccacagccatcatattaatgatggccgtgttcaacatgtttttc
ctgagtgactcagaggaaacaatccctccaactgccaacacaacaaacacaagcttttca
gcctcaaataatcaggtggcgattctgcgtgcgcaaaatttatttttcctcccgtacttt
atctacagctgcattctgggactgatatcctgttccgtgttcctgcgggtaaactatgag
ctgaagatgttgatcatgatggtggccttggtgggctacaacaccatcctactccacacc
cacgcccgcgtcctgggcgactacagccaggtcttatttgagagaccaggcatttggaaa
gacctgaagaccatgggctctgtgtctctctctatattcttcatcacactgcttgttctg
ggtagacagaatgaatattactgtaggttagacttcttatggaagaacaaattcaaaaaa
gagcgggaggagatagagaccatggagaacctgaaccgcgtgctgctggagaacgtgctt
cccgcgcacgtggctgagcacttcctggccaggagcctgaagaatgaggagctataccac
cagtcctatgactgcgtctgcgtcatgtttgcctccattccggatttcaaagaattttat
acagaatccgacgtgaacaaggagggcttggaatgccttcggctcctgaacgagatcatc
gctgactttgatgatcttctttccaagccaaaattcagtggagttgaaaagattaagacc
attggcagcacatacatggcagcaacaggtctgagcgctgtgcccagccaggagcactcc
caggagcccgagcggcagtacatgcacattggcaccatggtggagtttgcttttgccctg
gtagggaagctggatgccatcaacaagcactccttcaacgacttcaaattgcgagtgggt
attaaccatggacctgtgatagctggtgtgattggagctcagaagccacaatatgatatc
tggggcaacactgtcaatgtggccagtaggatggacagcaccggagtcctggacaaaata
caggttaccgaggagacgagcctcgtcctgcagaccctcggatacacgtgcacctgtcga
ggaataatcaacgtgaaaggaaagggggacctgaagacgtactttgtaaacacagaaatg
tcaaggtccctttcccagagcaacgtggcatcctga

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