KEGG T02442: 101145831

Gorilla gorilla gorilla (western lowland gorilla): 101145831

Entry

101145831         CDS       T02442

Symbol

KDM6A

Name

(RefSeq) lysine-specific demethylase 6A isoform X15

K11447

lysine-specific demethylase 6A [EC:1.14.11.68]

Organism

ggo Gorilla gorilla gorilla (western lowland gorilla)

Pathway

ggo05202

Transcriptional misregulation in cancer

Brite

KEGG Orthology (KO) [BR:ggo00001]
09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    101145831 (KDM6A)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ggo03036]
    101145831 (KDM6A)
Enzymes [BR:ggo01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.68  [histone H3]-trimethyl-L-lysine27 demethylase
     101145831 (KDM6A)
Chromosome and associated proteins [BR:ggo03036]
Eukaryotic type
  Histone modification proteins
   HMT complexes
    MLL3/MLL4 complex
     101145831 (KDM6A)
   Histone demethylases
    101145831 (KDM6A)

SSDB

Motif

Pfam:

KDM6_C-hel JmjC TPR_1 KDM6_GATAL TPR_2 TPR_8 TPR_16 TPR_17 TPR_12 TPR_19 TPR_CcmH_CycH TPR_7 TPR_9 TPR_11 ARM_TT21_C ANAPC3

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

X:join(55263832..55263992,55264204..55264267,55350857..55350965,55364233..55364282,55400548..55400606,55410194..55410314,55424563..55424617,55427283..55427317,55438383..55438476,55440516..55440642,55445660..55445758,55445902..55446121,55447981..55448076,55449308..55449409,55450087..55450482,55456245..55457023,55464042..55464171,55465744..55465849,55466492..55466697,55469900..55469964,55470039..55470113,55470776..55470924,55473201..55473315,55477081..55477268,55478057..55478198,55494812..55494938,55496806..55496976,55498109..55498138)

AA seq 1356 aa
MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQNTSDNWSGGHAVSHPPVQQQAH
SWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVGQVRSTGIPN
GPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTL
GSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHK
GQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTAT
SGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHG
DSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAIST
ATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSM
SVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYL
ENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLL
QPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSES
TSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHT
ILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNN
LNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLT
ACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQT
LREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKT
SGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS

NT seq 4071 nt +upstreamnt +downstreamnt
atgaaatcctgcggagtgtcgctcgctaccgccgccgctgccgccgccgctttcggtgat
gaggaaaagaaaatggcggcgggaaaagcgagcggcgagagcgaggaggcgtcccccagc
ctgacagccgaggagagggaggcgctcggcggactggacagccgcctctttgggttcgtg
aggtttcatgaagatggcgccaggacgaaggccctactgggcaaggctgttcgctgctat
gaatctctaatcttaaaagctgaaggaaaagtggagtctgatttcttttgtcaattaggt
cacttcaacctcttattggaagattatccaaaagcattatctgcataccagaggtactac
agtttacagtctgactactggaagaatgctgcctttttatatggtcttggtttggtctac
ttccattataatgcatttcagtgggcaattaaagcatttcaggaggtgctttatgttgat
cccagcttttgtcgagccaaggaaattcatttacgacttgggcttatgttcaaagtgaac
acagactatgagtctagtttaaagcattttcagttagctttggttgactgtaatccctgc
actttgtccaatgctgaaattcaatttcacattgcccacttatatgaaacccagaggaaa
tatcattctgcaaaagaagcttatgaacaacttttgcagacagagaatctttctgcacaa
gtaaaagcaactgtcttacaacagttaggttggatgcatcacactgtagatctcctggga
gataaagccaccaaggaaagctatgctattcagtatctccaaaagtccttggaagcagat
cctaattctggccagtcctggtatttcctcggaaggtgctattcaagtattgggaaagtt
caggatgcctttatatcttataggcagtctattgataaatcagaagcaagtgcagataca
tggtgttcaataggtgtgctatatcagcagcaaaatcagcccatggatgctttacaggcc
tatatttgtgctgtacaattggaccatggccatgctgcagcctggatggacctaggcact
ctctatgaatcctgcaaccagcctcaggatgccattaaatgctacttaaatgcaactaga
agcaaaagttgtagtaatacctctgcacttgcagcacgaattaagtatttacagaatact
tctgacaattggagtggtggacatgctgtgtcacatcctccagtacagcaacaagctcat
tcatggtgtttgacaccacagaaattacagcatttggaacagctccgcgcaaatagaaat
aatttaaatccagcacagaaactgatgctggaacagctggaaagtcagtttgtcttaatg
caacaacaccaaatgagaccaacaggagttggacaggtacgatctactggaattcctaat
gggccaacagctgactcatcactgcctacaaactcagtctctggccagcagccacagctt
gctctgaccagagtgcctagcgtctctcagcctggagtccgtcctgcctgccctgggcag
cctttggccaatggacccttttctgcaggccatgttccctgtagcacatcaagaacgctg
ggaagtacagacactattttgataggcaataatcatataacaggaagtggaagtaatgga
aacgtgccttacctgcagcgaaacgcactcactctacctcataaccgcacaaacctgacc
agcagcgcagaggagccgtggaaaaaccaactatctaactccactcaggggcttcacaaa
ggtcagagttcacattcggcaggtcctaatggtgaacgacctctctcttccactgggcct
tcccagcatctccaggcagctggctctggtattcagaatcagaacggacatcccaccctg
cctagcaattcagtaacacagggggctgctctcaatcacctctcctctcacactgctacc
tcaggtggacaacaaggcattaccttaaccaaagagagcaagccttcaggaaacatattg
acggtgcctgaaacaagcaggcacactggagagacacctaacagcactgccagtgtcgag
ggacttcctaatcatgtccatcagatgacggcagatgctgtttgcagtcctagccatgga
gattctaagtcaccaggtttactaagttcagacaatcctcagctctctgccttgttgatg
ggaaaagccaataacaatgtgggtactggaacctgtgacaaagtcaataacatccaccca
gctgttcatacaaagactgataactctgttgcctcttcaccatcttcagccatttccaca
gcaacaccttctccaaaatccactgagcagacaaccacaaacagtgttaccagccttaac
agccctcacagtgggctacacacaattaatggagaagggatggaagaatctcagagcccc
atgaaaacagatctgcttctggttaaccacaaacctagtccacagatcataccatcaatg
tctgtgtctatataccccagctcagcagaagttctgaaggcatgcaggaatctaggtaaa
aatggcttatctaacagtagcattttgttggataaatgtccacctccaagaccaccatct
tcaccataccctcccttgccaaaggacaagttgaatccacctacacctagtatttacttg
gaaaataaacgtgatgctttctttcctccattacatcaattttgtacaaatccgaacaac
cctgttacagtaatacgtggccttgctggagctcttaagttagacctgggacttttctct
actaaaactttggtggaagctaacaatgaacatatggtagaagtgaggacacagttgttg
cagccagcagatgaaaactgggatcccactggaacaaagaaaatctggcattgtgaaagt
aatagatctcatactacaattgctaaatatgcacagtaccaggcctcctcattccaggaa
tcattgagagaagaaaatgaaaaaagaagtcatcataaagaccactcagatagtgaatct
acatcgtcagataattctgggaggaggaggaaaggaccctttaaaaccataaagtttggg
accaatattgacctatctgatgacaaaaagtggaagttgcagctacatgagctgactaaa
cttcctgcttttgtgcgtgtcgtatcagcaggaaatcttctaagccatgttggtcatacc
atattgggcatgaacacagttcaactatacatgaaagttccagggagcagaacaccaggt
catcaggaaaataacaacttctgttcagttaacataaatattggcccaggtgactgtgaa
tggtttgttgttcctgaaggttactggggtgttctgaatgacttctgtgaaaaaaataat
ttgaatttcctaatgggttcttggtggcccaatcttgaagatctttatgaagcaaatgtt
ccagtgtataggtttattcagcgacctggagatttggtctggataaatgcaggcactgtt
cattgggttcaggctattggctggtgcaacaacattgcttggaatgttggtccacttaca
gcctgccagtataaattggcagtggaacggtacgaatggaacaaattgcaaagtgtgaag
tcaatagtacccatggttcatctttcctggaatatggcacgaaatatcaaggtctcagat
ccaaagctttttgaaatgattaagtattgtcttctaagaactctgaagcaatgtcagaca
ttgagggaagctctcattgctgcaggaaaagagattatatggcatgggcggacaaaagaa
gaaccagctcattactgtagcatttgtgaagtggaggtttttgatctgctttttgtcact
aatgagagtaattcacgaaagacctacatagtacattgccaagattgtgcacgaaaaaca
agcggaaacttggaaaactttgtggtgctagaacagtacaaaatggaggacctgatgcaa
gtctatgaccaatttacattagctcctccattaccatccgcctcatcttga

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