Gorilla gorilla gorilla (western lowland gorilla): 109024862
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Entry
109024862 CDS
T02442
Symbol
IRS4
Name
(RefSeq) insulin receptor substrate 4 isoform X2
KO
K17446
insulin receptor substrate 4
Organism
ggo
Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04022
cGMP-PKG signaling pathway
ggo04068
FoxO signaling pathway
ggo04081
Hormone signaling
ggo04140
Autophagy - animal
ggo04152
AMPK signaling pathway
ggo04211
Longevity regulating pathway
ggo04213
Longevity regulating pathway - multiple species
ggo04910
Insulin signaling pathway
ggo04920
Adipocytokine signaling pathway
ggo04923
Regulation of lipolysis in adipocytes
ggo04930
Type II diabetes mellitus
ggo04935
Growth hormone synthesis, secretion and action
ggo05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
ggo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
109024862 (IRS4)
04022 cGMP-PKG signaling pathway
109024862 (IRS4)
04152 AMPK signaling pathway
109024862 (IRS4)
09133 Signaling molecules and interaction
04081 Hormone signaling
109024862 (IRS4)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
109024862 (IRS4)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
109024862 (IRS4)
04923 Regulation of lipolysis in adipocytes
109024862 (IRS4)
04920 Adipocytokine signaling pathway
109024862 (IRS4)
04935 Growth hormone synthesis, secretion and action
109024862 (IRS4)
09149 Aging
04211 Longevity regulating pathway
109024862 (IRS4)
04213 Longevity regulating pathway - multiple species
109024862 (IRS4)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
109024862 (IRS4)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
109024862 (IRS4)
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Motif
Pfam:
IRS
PH_11
PH_8
PH
Motif
Other DBs
NCBI-GeneID:
109024862
NCBI-ProteinID:
XP_030861776
Ensembl:
ENSGGOG00000038822
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Position
X:complement(join(120516014..120516018,120526090..120529855))
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AA seq
1256 aa
AA seq
DB search
MASCSFTRDQATRRLRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTAT
GSRSDSESEEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH
SVRAAAAAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV
AENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVK
PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST
VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRH
LGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLFTRRFVTPSEPVAHSRRGRLHLPRGR
RSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNSGEEGNPQGKEDQ
EGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGS
GGNHCSGDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGS
DGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGATGGKGKSGGRFRLYFCAD
RGATKERKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVPAPLVSSSDYMPM
APQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYM
FMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQSDNSEYVPMLPGKFLGRG
LDKEVSYNWDPKDAASKPLGEGSFSKPGDGGSPSKPSDDEPPKNKAKRPNRLSFITKGYK
IKPKPQKPTHEQREADSSSDYVNMDFTTRESNTPAPSTQGLPDSWGIIAEPRQSAFSNYV
NVEFGVPFPNPANDLSDLLRAIPRANPLSLDSARWPLPPLPLSATGSNAIEEEGDYIEVI
FNSAMTPAMALADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEEQ
GRRRPQNRSQSFFAAARAAVSAFPTDSLERDLSPSSAPAVASAAEPTLALSQVVAAASAL
AAAPGIGAAAAAAGFDSASARWFQPVANAADAEAIRGVQDVAGGSNTGAHNPSANLARGD
NQAGGAAAAAAAPEPPPRSRRVPRPPEREDSDNDDDTYVRMDFARRDNQFDSPKRE
NT seq
3771 nt
NT seq
+upstream
nt +downstream
nt
atggcgagttgctccttcactcgcgaccaagcgacaagaagactaagaggtgcagcagcg
gcagcagcggcagctctagcagcagtggtgaccaccccgcttctttcctcgggaaccccg
accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccacggccact
ggctcccggtcagactccgagtccgaggaggaggacctgcccgtcggggaggaagtctgc
aaacgcggctacctgcggaaacagaagcatgggcacaggcgctacttcgtgctcaaactc
gagactgctgacgccccagctcggctggaatactacgaaaatgccaggaagttccggcac
agtgtccgcgccgcggcggctgcagcagcggcggccgcctctggcgccgcgatccccccg
ctcattccaccgcggcgcgtgatcaccctataccagtgcttttccgtgagccagcgagca
gatgcaaggtaccgacacctcattgctcttttcacccaagacgaatacttcgcgatggtg
gccgagaacgagtcggagcaggaaagctggtacttgctgctcagccgcctcatcctcgag
agcaagcgccgccgctgcggcacgctcggcgcgcagccggacggagagccggccgcgctg
gcggcggcagcggcggcggagccacccttctataaagatgtgtggcaggtaatagtcaaa
cccagggggctggggcacagaaaagagctgagcggcgtgttccggctgtgtctaaccgac
gaggaggtcgtgtttgtgaggctgaacaccgaagtagccagcgtggtcgtccagctcctg
agcatccgtcgctgtggacactcggagcagtatttcttcttggaagtaggcaggtccact
gtcatcggtccgggagagctctggatgcaggtcgatgactgcgtggttgcccaaaacatg
catgagctgtttttggagaagatgagagccttgtgtgcagacgaatacagagcccgctgc
cgcagctacagcatcagcatcggcgcccacctgttaaccctgctgtccgctaggaggcac
ctgggcttggtgccgctcgagccgggaggctggctcagaaggtcccgctttgagcagttt
tgccacctcagggccatcggcgacggggaagacgagatgcttttcaccaggcgcttcgta
acacccagcgagcctgtggcccactccaggcgaggaagactgcacctgcccagagggcgc
aggtcaaggagagcggtttcagtgccggccagcttttttcgccgcttagcacccagccca
gcacgtccccggcaccctgcagaagccccgaacaatggagctcgcctgtcttctgaagtg
tctggctctggctctggcaactctggggaggaaggcaatccccagggcaaagaagatcag
gaaggaagcggaggtgactacatgcccatgaacaattggggctcaggaaatggccggggc
tcaggaggtggccagggctcaaatggacaaggctccagtagccatagctcgggaggaaac
cagtgttcaggcgagggacagggatcccgaggtggtcagggctcaaatggccagggctca
ggaggaaaccattgctctggagatggccagggcaccgcaggtgggcacggttcaggtggt
ggccagagacctggaggtgggcatggctcaggtggtggccagggacctggagatggccat
ggctcaggtggtggcaagaactctggagggggcaaaggctcaggaagtgggaaaggatcc
gatggtgatggtgaacgtggaaaatctctgaagaaaagatcctattttggcaaattaact
caaagcaagcaacagcaaatgccaccacctccaccacctcctcctccacccccaccagct
ggagcaactggtggaaaagggaagtctgggggaagattccgactttatttttgtgctgac
agaggagccacaaaagaacgcaaagaagccaaagaagtgaaagatgcagagatcccagaa
ggtgcagctcgaggtccccacagagccagagcttttgatgaagatgaggatgacccatac
gtgccaatgaggccaggggtgcccgcccctcttgtaagctccagtgattatatgccaatg
gctcctcaaaatgtctctgcttcaaaaaagcgccactctcgatccccttttgaagattca
agagggtacatgatgatgtttcccagagtgagcccaccacctgctccgagtcctccaaaa
gcacctgatactaataaagaggatgactcaaaggacaatgacagtgagagtgactacatg
tttatggctcctggagccggtgcaattccaaaaaaccccagaaatcctcagggtggctct
tcctccaaaagttggagctcctacttctctctaccgaacccttttcggagctcacctttg
ggacagagtgacaacagtgagtatgtgccaatgttacctggaaagttcctggggaggggc
ctagacaaagaagtctcctataactgggaccccaaagatgcagcttcaaagcctttaggt
gagggatcattctcaaagcctggagatgggggatcaccttcaaagccttcagatgatgag
cccccaaagaataaagctaagagacctaaccgactttcttttattacaaaaggatataaa
atcaagccaaaaccacaaaagcccacacatgagcagagagaagctgacagctctagtgac
tacgtcaacatggacttcactacaagagagagcaatacaccagctccctctactcaaggg
ctaccagattcgtggggcataattgctgaacccagacagtcagccttttctaattatgtg
aatgttgagtttggagtgccatttccaaatccagcaaacgacctctcagatcttttaaga
gctataccacgtgccaaccccttatctctggacagtgctaggtggccacttcctcccctt
cccctcagtgctacaggtagcaatgctattgaggaagagggtgactacattgaagtaatt
ttcaactcagcaatgacaccagccatggctcttgctgacagtgccattcgctatgatgct
gaaacaggtcgaatctatgtggtcgacccattttctgagtgctgtatggatatttctctc
tcccccagccgatgttctgaaccaccacctgtagctaggctgctgcaggaggaagagcag
gggagaagacgcccacaaaaccgttctcaaagtttctttgcagcagccagagccgctgtc
tctgcttttccaacagacagcctcgagagagacctttccccatcctcagccccggctgtc
gcttcggctgcagagccgactttagccctcagccaagttgtagctgcggcctccgcgctc
gccgcagccccgggcatcggcgcagcagccgcagctgctggatttgactccgcctctgcc
cgctggtttcaacctgttgctaatgctgctgatgccgaagcaataaggggagtccaagac
gttgccggtggctcgaacactggagcccacaacccatctgcaaaccttgccagaggtgat
aaccaggctggcggggctgccgctgcagctgccgctccggaaccaccacctcgcagtcgc
cgggtgccaagacccccggagagagaagattctgacaacgacgacgacacttacgtgaga
atggattttgccagacgtgataaccagttcgactctcccaaaagagagtga
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