Glycomyces sp. TRM65418: K3N28_04770
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Entry
K3N28_04770 CDS
T07425
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
gly
Glycomyces sp. TRM65418
Pathway
gly00020
Citrate cycle (TCA cycle)
gly00630
Glyoxylate and dicarboxylate metabolism
gly00785
Lipoic acid metabolism
gly01100
Metabolic pathways
gly01110
Biosynthesis of secondary metabolites
gly01120
Microbial metabolism in diverse environments
gly01200
Carbon metabolism
gly01210
2-Oxocarboxylic acid metabolism
Module
gly_M00009
Citrate cycle (TCA cycle, Krebs cycle)
gly_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
gly00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
K3N28_04770
00630 Glyoxylate and dicarboxylate metabolism
K3N28_04770
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K3N28_04770
Enzymes [BR:
gly01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
K3N28_04770
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
K3N28_04770
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
K3N28_04770
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
K3N28_04770
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GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QZD56434
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Position
1046453..1050160
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AA seq
1235 aa
AA seq
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MYERYRENPDSVSAGWREFFGGDPQHTSFADDGATRAAAEPAAAKPAEAAPARKPEPVAA
APATRSDEPEPAKPAAEPAAASPSSATRADRASDETEPAKKATPHVNEPAATDGSAGAVT
KPLKGVAAKVAQNMDASLEIPTATSVRAIPAKLLFDNRIVINNHLKRGQGGKVSFTHLIG
YALVQAVKAHPGMNASYKVVDGKPQLVTPEHINLGLAIDLSRPDGTRTLVVPSIKNCESM
DFREFFQAYEDLVRKARSNKLTMEDHAGATLTLTNPGGIGTVHSVPRLMKGQGLIVGVGA
MEVPAEFAGASDETLSDLGVSRIMTVTSTYDHRIIQGAESGQFLATLHRLLLGDAFFDEV
FRSLMIPYEPVRWVRDVSKTHEGQIDKNARVIELIHAYRVRGHLMADTNPLHYEIRRHPD
LDILSHGLTLWDLDRTFPVGGFAGQQRMKLRDILGVLRDSYCRRVGVEYMHIQDPEERSW
IQRRIEVPFEKPKVEEQKHILGRLNAAEAFETFLQTKFVGQKRFSLEGGESLIPLLDRVL
NEAATADIDEVVIGMPHRGRLNVLANIVGKKLSKIFTEFEGHIDPKSIGGSGDVKYHLGL
TGKFTSPDGRHETVVSVAANPSHLEAVNPVLEGIVRAKQDRLDLGEDGFTVMPVAIHGDA
AFAGQGVVAETLNLSQLRGYRTGGTVHVVVNNQVGFTTAPAYSRSSLYCTDVARMIQAPI
FHVNGDDPEAVCEVAKLAFAYRQQFRKDVVIDMVCYRRRGHNEGDDPKMTNPQMYQVIDG
KQSVRKLYTRALIGRGDITMEDAEEALADYQAQLERVFRETKEALAGQTGPLPWRHQPEP
VADIDTAVDAETIAMIGKAHTTLPEGFTPHKAVRKVLEKRSEMSTSGTVDWAFAETLAFG
SLLMQGKAVRLAGQDSRRGTFVQRHAVVVDQATGAEYTPLAHLGEQAAKFFVYDSLLSEF
AALGFEYGYSVENPEMLVLWEAQFGDFVDGAQTITDEFISSGEAKWGQHSGVTLLLPHGH
EGAGPDHTSGRIERFLQLCADENMRVVNSTSPANYFHLLRRQALDPVKKPLVVFTPKSLL
RHKAAVSPLEEFTSGGFRPVLTDPAVASGQIRPEDVKRVLLCAGKVYYDLAAARQSRGVT
DTAILRVEQLYPLPAEELKRALGAFPNAEDTAWVQEEPANQGAWSHIALNLLEQLGGVHL
RRISRPAAAAPSTGSPKVHEVEQQALVDVAVPQPQ
NT seq
3708 nt
NT seq
+upstream
nt +downstream
nt
atgtatgagcgttaccgcgaaaaccccgacagtgtcagcgccgggtggcgcgaattcttc
ggcggcgatccccagcacacgtcgttcgccgacgacggcgcgacccgggcggcggccgag
cccgcggcggcgaagcccgccgaagcggctcccgcccggaagcccgagccggtcgcggcg
gcgcccgcgacgcgatccgacgagcccgagccggcgaagcccgcggccgagcccgccgct
gcgtccccctcctcggcgacgcgcgccgaccgcgcgtcggacgagaccgaacctgcgaag
aaggcgactccacacgtgaacgaacccgccgcgaccgacggctccgcaggcgccgtgacc
aagccgctcaaaggcgtcgccgccaaggtcgcccagaacatggacgcgtccctggagatc
cccacggccacctcggtccgggcgatccccgcgaagctcctgttcgacaaccggatcgtc
atcaacaaccacctcaagcgcggccagggcgggaaggtctccttcacgcacctcatcggc
tacgcgctggtgcaggccgtcaaggcccacccgggcatgaacgcctcctacaaggtcgtc
gacggcaagccgcagctggtcacgcccgagcacatcaacctcggcctcgcgatcgacctg
tcccggcccgacggcacccgcacgctcgtggtcccgtcgatcaagaactgcgagtccatg
gacttccgcgagttcttccaggcctacgaggacctggtccgcaaggcccggagcaacaag
ctcacgatggaggaccacgccggggcgacgctgacgctcaccaatcccggcggcatcggc
accgtccactccgtcccgcgcctgatgaagggccagggcctcatcgtcggcgtcggcgcc
atggaggtgcccgccgaattcgccggagcctccgacgagaccctgtccgacctgggcgtc
tcccggatcatgacggtgacgtcgacctatgaccaccggatcatccagggcgccgagtcc
ggccagttcctcgcgaccctgcaccggctgctgctcggcgacgcgttcttcgacgaggtc
ttccgctcgctgatgatcccctacgagccggtgcgctgggtccgcgacgtctcgaagacc
cacgagggccagatcgacaagaacgcccgggtcatcgagctcatccacgcctaccgggtc
cgcggccacctcatggccgacaccaacccgctgcactacgagatccgccgccaccccgac
ctcgacatcctgtcgcacggcctcaccctgtgggacctggaccggaccttccccgtgggc
ggcttcgcgggccagcagcgcatgaagctgcgcgacatcctcggcgtcctgcgcgactcc
tactgccgtcgcgtcggcgtggagtacatgcacatccaggaccccgaggagcgctcctgg
atccagcgccgcatcgaggtcccgttcgagaagccgaaggtcgaggagcagaagcacatc
ctcgggcggctcaacgccgccgaggccttcgagacgttcctgcagaccaagttcgtcggc
cagaagcgcttcagcctcgaaggcggcgagtcgctcatcccgctgctcgaccgcgtcctc
aacgaggccgcgaccgccgacatcgacgaggtcgtcatcggcatgccccaccgcgggcgc
ctgaacgtcctcgccaacatcgtcggcaagaagctctccaagatcttcaccgagttcgag
gggcacatcgaccccaagagcatcggcggctccggcgacgtcaagtaccacctgggcctc
accggcaagttcacctcccccgacgggaggcacgagaccgtcgtgtcggtcgcggcgaac
ccctcgcacctggaggccgtgaacccggtgctcgaagggatcgtgcgcgccaagcaggac
cggctcgacctcggcgaggacggcttcaccgtcatgcccgtggcgatccacggcgacgcg
gccttcgcgggccagggcgtggtggccgagacgctgaacctctcgcagctgcgcggctac
cgcaccggcggcaccgtgcacgtcgtcgtcaacaaccaggtcggcttcaccaccgccccg
gcgtactcgcgctcgagcctgtactgcaccgacgtcgcccgcatgatccaggcgccgatc
ttccacgtcaacggggacgaccccgaggccgtgtgcgaggtcgcgaagctcgcgttcgcc
taccgccagcagttccgcaaggacgtcgtcatcgacatggtctgctaccgccggcgcggc
cacaacgagggcgacgaccccaagatgaccaacccgcagatgtaccaggtcatcgacggc
aagcagtccgtgcgcaagctctacacccgcgcgctcatcggccgcggcgacatcaccatg
gaggacgccgaggaggcgctcgcggactaccaggcccagctcgaacgggtcttccgcgag
accaaggaggccctggccgggcagaccggcccgctgccgtggcgccaccagcccgagccc
gtggccgacatcgacaccgccgtcgacgccgagaccatcgcgatgatcggcaaggcccac
accacgctgccggagggcttcacgccgcacaaggccgtccgcaaggtcctcgagaagcgc
agcgagatgtccacgtccggcaccgtcgactgggcgttcgccgagaccctcgcgttcggg
tcgctcctcatgcagggcaaggccgtgcgcctcgccgggcaggactcgcggcgcggcacg
ttcgtgcagcgccacgcggtcgtcgtcgaccaggccaccggcgcggagtacacgccgctg
gcccacctgggcgagcaggccgcgaagttcttcgtctacgactcgctgctcagcgagttc
gccgcgctcggcttcgagtacggctactcggtggagaaccccgagatgctcgtcctgtgg
gaggcccagttcggcgacttcgtcgacggcgcccagaccatcaccgacgagttcatctcc
tcgggcgaggccaagtggggccagcactccggcgtcacgctgctgctgccgcacggccac
gagggcgcgggccccgaccacacctcgggccgcatcgagcggttcctgcagctgtgcgcc
gacgagaacatgcgcgtggtcaactccacgagcccggccaactacttccacctgctgcgc
cgccaggccctcgacccggtcaagaagcccctggtcgtcttcaccccgaagtcgctgctg
cgccacaaggccgcggtcagcccgctcgaggagttcaccagcggcggcttccggccggtc
ctcaccgacccggccgtcgcgagcggccagatccggccggaggacgtcaagcgggtcctg
ctgtgcgcgggcaaggtctactacgacctggccgccgcccgccagagccgcggcgtcacc
gacaccgcgatcctccgcgtcgagcagctctacccgctgccggccgaggagctgaagcgc
gccctcggcgccttcccgaacgcggaggacaccgcgtgggtccaggaggagccggcgaac
cagggcgcctggtcgcacatcgcgctcaacctgctggaacagctcggcggggtccacctg
cgccgcatctcgcgcccggccgccgccgcgccgtccaccggctcgccgaaggtccacgaa
gtcgagcagcaggcgctcgtcgacgtcgcggtgccgcagccgcagtag
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