KEGG   Geobacter metallireducens: Gmet_0549
Entry
Gmet_0549         CDS       T00295                                 
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine S-methyltransferase, cobalamin-dependent
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
gme  Geobacter metallireducens
Pathway
gme00270  Cysteine and methionine metabolism
gme00450  Selenocompound metabolism
gme00670  One carbon pool by folate
gme01100  Metabolic pathways
gme01110  Biosynthesis of secondary metabolites
gme01230  Biosynthesis of amino acids
gme04980  Cobalamin transport and metabolism
gme04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:gme00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Gmet_0549 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Gmet_0549 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Gmet_0549 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Gmet_0549 (metH)
   04980 Cobalamin transport and metabolism
    Gmet_0549 (metH)
Enzymes [BR:gme01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Gmet_0549 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind B12-binding B12-binding_2 CdhD NAD_binding_10
Other DBs
NCBI-ProteinID: ABB30792
UniProt: Q39Y82
LinkDB
Position
585401..587815
AA seq 804 aa
MKTPFLQAIKERVLVLDGAMGTMLQERGLRPGQSPEELNLTMPDVVAGVHREYLEAGADI
IVTNTFGGTRPKLEHYGLEEKVREINARAVEIAREVCGDRAYVAASMGPTGLFVEPVGEA
TFDAMAAFFREQAAALIEAGADLITLETFLDIKEIRAAVIAIREVSPTIPVIAQLTFDNE
GRTVLGTPPEAAAVTLAAAGADIVGSNCGLGPDGICAVLGAMRGVTRLPLISQANAGLPK
LVDGKTVFPGTPDDMTAFHDRMLGLNVRVIGGCCGTTPTHIRAIKEALAGRDQSWRDCGP
PAGVTFLASRTSVVALGGGLPAAIIGERINPTGKKAFAQELREGKITTIRREAMEQTAAG
AHLLDVNVGTPGIDEPAAMERAVFCVTGSVAVPLVLDSSDPAALERGLKAADGKVLVNSV
NGETKSIERVLPLVKKYGAAVIGLALDETGIPETAEGRLAVAERIVAAAEGRGISRNDVV
IDCLTLTVSAEQKRAMETLRAVRLVKEIIGCPTVLGVSNISFGLPRRPLISSAFFAMALA
AGLDAAIVNPKEEEMMAAWRSAMVLLNRDPSAAAYIAAYAGTAAAAPEPAASGEALDIRE
RLKRAVITGDRENIVALVEEALGQGLEPLQVSNEGLLPGLEEVGRRFEKNLVFLPQVMQS
ADTMQAAFGRLREVMKGSPAASRGKILMATVEGDIHDIGKNIVCTLLENHGFEVIDLGKN
VPADRIVGKARELGVDAVGLSALMTTTMTEMENVIARLKEAGIRTFTMVGGAVVTQEYAD
EIGADLYARDAMEAVARIKALLEK
NT seq 2415 nt   +upstreamnt  +downstreamnt
atgaaaacaccctttctgcaggcgatcaaagaacgggtcctggtccttgacggggccatg
gggaccatgctccaggagcgggggctgcgccccggccagtcccccgaagagctgaacctc
accatgcccgacgtggtggccggggtccatcgggaatatctggaggctggggccgacatc
atcgtcaccaacaccttcggcggcacccgccccaagctggagcactacggcctggaggag
aaggtccgcgagatcaacgcccgggccgtggagatcgcccgggaggtttgcggcgaccgg
gcctacgtggccgcctccatggggcccacggggctcttcgtggagccggtgggggaggcg
accttcgacgccatggccgccttcttccgggaacaggccgcggccctcatcgaagccggc
gccgacctcatcaccctggagaccttcctcgacatcaaggagatccgggcagcggtcatc
gccatccgtgaggtctctcccacgatccccgtcatcgcccagctcaccttcgacaacgag
ggacgcactgtcctcggcaccccccccgaagcggcggccgtgaccctagcggcggccggg
gccgacatcgtcggctccaactgcggtctcggtcccgatggcatctgcgccgtcctggga
gccatgcgtggggtgacccggcttcccctcatttcccaggccaacgcggggctgccgaag
ctggtggacggcaagaccgtcttccccggcacccccgacgacatgaccgccttccacgac
cggatgctgggactgaacgtgcgggtcattggcggttgctgcggcaccaccccgacccac
atccgggccatcaaggaggccctggcggggcgcgaccagtcgtggcgcgactgcggcccc
ccggccggggtcacgttcctggcgagccgcacctcggtcgtcgccctcggcgggggcctt
cccgcggccatcatcggcgagcggatcaaccccaccggcaagaaggcctttgcccaggag
ctgcgggaggggaagattaccaccatccgccgcgaggccatggaacagacggctgccggc
gcccacctcctggacgtgaacgtggggaccccggggatcgacgagcctgccgccatggag
cgggcggtcttctgtgttaccggaagcgtcgccgtgccgctggtcctcgattcttccgat
ccggcggccctggaacggggactcaaggcggccgacggcaaggttctcgtgaactccgtg
aacggcgagacgaagagcatcgagcgggtcctccccctggtgaagaagtacggcgccgcc
gtcatcggcctggccctggacgagaccggtatccccgagaccgccgaggggcgcctggcc
gtggcggaacggatcgtggccgctgcggaagggcgcggcatctcccgcaacgacgtggtg
attgattgcctgaccctcaccgtgagcgctgagcagaagcgggccatggaaaccctgcgg
gcggtgcgcctcgtgaaggagatcattggctgccccacggtcctcggcgtcagcaacatc
tccttcggccttccccgccgtcccctcatctcttcggccttcttcgccatggccttggcc
gcggggctcgacgccgccatcgtcaacccgaaggaggaggagatgatggcggcctggcgt
tcggccatggtcctcctgaaccgggaccccagcgctgccgcgtacatcgctgcctacgcc
gggacggccgccgctgcccctgaaccggcagcgtccggcgaggccctcgacattcgggag
cgcttgaagcgtgccgtcatcaccggcgacagggagaatatcgttgcgttggttgaggag
gcgcttggccaggggctcgaaccgctccaggtgagcaacgaagggctcctccccggcctg
gaggaggtggggcggcgcttcgagaagaacctcgtcttccttccccaggtgatgcagtcg
gccgacacgatgcaggccgccttcggccgcctcagggaggtcatgaagggttctcccgcc
gccagccgggggaagatcctcatggccaccgtcgagggggacatccacgatatcggcaag
aatatcgtctgcacgctcctggagaaccacggcttcgaggtgatcgatctggggaagaac
gtccctgccgaccggatcgtgggaaaggcccgggaattgggcgtcgatgccgtggggctc
tcggccctcatgaccaccaccatgaccgagatggagaatgtgattgcgcggctgaaggag
gccggcatccggacgttcaccatggtggggggggcggtggtgacccaggagtacgccgac
gagattggcgccgatctctacgcccgggacgccatggaggcggtggcgcggatcaaggcg
ctgctggagaagtag

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