KEGG   Geobacter metallireducens: Gmet_0810
Entry
Gmet_0810         CDS       T00295                                 
Symbol
acrB
Name
(GenBank) efflux pump, RND family, inner membrane protein
  KO
K18138  multidrug efflux pump
Organism
gme  Geobacter metallireducens
Pathway
gme01501  beta-Lactam resistance
gme01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:gme00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    Gmet_0810 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    Gmet_0810 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:gme02000]
    Gmet_0810 (acrB)
   01504 Antimicrobial resistance genes [BR:gme01504]
    Gmet_0810 (acrB)
Transporters [BR:gme02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   Gmet_0810 (acrB)
Antimicrobial resistance genes [BR:gme01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    Gmet_0810 (acrB)
SSDB
Motif
Pfam: ACR_tran MMPL SecD_SecF_C
Other DBs
NCBI-ProteinID: ABB31052
UniProt: Q39XH2
LinkDB
Position
889352..892513
AA seq 1053 aa
MSRFFINRPIFAWVIAIMVMLAGLLAIKTLPVSQYPPIAPPQITINAMYPGASAQTVQDT
VTQVIEQKLNGIDNLIYMSSTSDSAGAVAINLTFKAGTDPNIAQVQVQNKLQLATPLLPQ
IVQKQGIQVVKSTKNFLLIVGVVSEDGSMDRPALTDYLVANVQDVISRTEGVGEVTVFGS
QNAMRIWLNPAKLNNYHLTTNDVIAAVQAQNAQVSAGQFGGNPAPPGQQLNATITARTLL
QTPEQFNAIILRTNPDGSTVRLKDVAECKIGTENYDIEARYKGKPMGGMALRLAAGANAL
DTADRVKAKMAELSKYFPAGMEVVYPYDTTPFVKVSIEEVVQTLIEAVFLVFIIMFLFLQ
NIRATLIPTIAVPVVLLGTMGALSAAGFSINTLTMFALVIVIGLLVDDAIVVVENVERIM
SEEGLSPHDATVKSMGQITSALWGIATVLSAVFLPMAFFGGSTGVIYRQFSITIISAMIL
SVMTAQILTPALCSTLLKPVEKGHEACETGWFCGFFRWFNKCFNWCRGRYEGIVGRSFGK
PVRYLVIYGVIVAAMAFFFLRLPTAFLPDEDQGFIVCQVQLPAGAAQERTITVLEQLEHH
FLEKEKKSVETIITIAGFSFAGRGQNMGLAFVRLKDWKLRPTPDMKAPAVAGRAMKAFSQ
IRDGLAFAFSPPAVVELGQANGFDFQLQDRAGLGHEKLMEARNQLLGMAMKNPKLIAVRP
NGQDDSPQFKLDIDDVRAGALGVNLADVNSVLATAWGSSYVNDFIENGRVKKVYLQAEPR
SRMLPEDINSWYVNNRNGEMVPFSAFATAHWKYGSPRLERYNGIPSVEIMGQAAPGVSTG
EAMVEMEKMAAQLPPGIGYEWTGLSYEEKQAGKQAPALYAISLLVVFLSVAALYESWTIP
FVNLLMLPLGLVGAVTAVKLRMLPNDVYLQIGLLTTVGLSTKNAILIIQFIKDQMHQGHE
LVEATLTAVKIRLRPVIMTSLAFFFGTLPLALTKGAGAAAQNAIGTAVTGGLLSATFIDL
IFIPFFFVMVSKVFAKKKQPSVQPAAEAASEVN
NT seq 3162 nt   +upstreamnt  +downstreamnt
atgtcccgctttttcataaacagacccatctttgcctgggtaatcgccatcatggtcatg
ctggccggcctcctggcgatcaagaccctgccggtctcccaataccctcccatcgcacca
ccccagatcaccatcaacgccatgtatcccggcgcctcggcccagacggtgcaggatacg
gtaacccaggtgatcgagcagaagctgaacgggatcgacaacctgatctacatgtcctcc
accagcgattcggccggcgccgtggccatcaacctcaccttcaaggccggcaccgacccg
aacatcgcccaggtgcaggtgcagaacaagctgcagctcgccacgccgctcctcccccag
atcgtccagaaacaggggattcaggtggtcaagtccaccaagaacttcctcctgatcgtc
ggggtcgtgtcggaggacggctccatggaccgcccggccctgaccgactatctggttgcc
aacgtccaggacgtcatcagcaggacggaaggggtcggcgaggtaacggtcttcggctcc
cagaacgccatgcggatctggctcaacccggccaagctcaacaactaccacctcaccacc
aacgacgtcatcgcggcggtgcaggcccagaacgcccaggtgtcagccggccagttcggc
gggaatccggcgcccccgggacagcagttgaacgccaccatcacggcccgcaccctcctc
cagacaccggagcagttcaacgccatcatcctgaggaccaaccccgacggttccacggtc
aggctgaaggatgtggccgaatgtaagatcggcaccgagaattacgatatcgaagcacgg
tacaagggaaaaccgatgggggggatggcgctgcgcctggccgcgggcgccaacgccctg
gacaccgccgaccgggtcaaggcgaagatggcggaactgtcgaaatacttccccgccggc
atggaggtggtctacccctacgacaccacccccttcgtcaaggtctccattgaagaggtg
gtccagaccctgatcgaggcggtcttcctcgtcttcatcatcatgttcctcttcctgcag
aatatccgggccaccctgatccccaccatcgccgttccggtcgtcctgctcggcaccatg
ggggcgttgtcggccgccggcttctccatcaacaccctgaccatgttcgccctggtcatc
gtcatcggcctcctggtggacgacgccatcgtcgtggtggagaacgtggaacggatcatg
tccgaggaggggctctcgccccacgacgccaccgtcaaatccatggggcagatcaccagt
gccctctgggggatcgccaccgtcctctcggcggtcttcctccccatggccttcttcggc
ggctccaccggcgtcatctaccgccagttctccatcaccatcatctccgccatgattctc
tcggtgatgacggcccagattctgacgccggccctctgctccaccctgctcaagccggtg
gagaaggggcatgaggcgtgcgagactggctggttctgcggtttcttccgctggttcaac
aaatgcttcaactggtgccggggcagatacgaagggatcgtcggccgttcattcggcaag
ccggtgcgctacctggtgatttacggggtcatcgtggcggccatggcgttcttcttcctg
cgccttcccaccgcattcctccccgacgaggaccaggggttcatcgtctgccaggtccag
ctccctgcaggggctgcccaggagcggactatcacagtgctcgagcagcttgaacaccac
ttcctggagaaggagaagaagtcggtggagacgatcattaccattgccggcttcagcttt
gccggccggggccagaacatggggcttgcctttgtcaggctcaaggactggaagctgcgc
ccgacccccgacatgaaggcgccggccgttgccggacgggccatgaaggctttctcgcag
atccgcgacggcctcgcctttgccttttcaccgccggcggtggtggagctggggcaggcc
aacggcttcgacttccagctgcaggaccgtgccggccttggccatgagaagctgatggag
gcccgcaaccagctcctcggcatggccatgaagaaccccaagctgatcgcggtgcgcccc
aacgggcaggatgattcgccccagttcaagctcgacattgacgacgtgcgggccggggcc
ctgggggtcaacctggccgatgtcaacagcgtactggccacggcctggggaagctcctac
gtcaacgacttcatcgagaacggtcgggtgaagaaggtctatctccaggctgaacccagg
tcccgcatgctgccggaggacatcaacagctggtacgtgaacaacagaaacggcgagatg
gtccccttctcggccttcgccaccgcccactggaagtacggctcgccccggcttgagcgt
tacaacggcattccgtccgtggagatcatgggacaggcggcgcccggggtgagcaccggc
gaggccatggtcgagatggagaagatggcggcccagcttccgccgggcatcggttacgag
tggaccggactctcctacgaggaaaaacaggccggcaagcaggcgcccgccctctacgcc
atctcgctcctggtggtgttcctctccgtggcggccctctacgaaagctggaccatcccc
ttcgtcaacctgctgatgcttcccctcggcctggtgggggcggtcacggcggtgaagctg
cggatgcttcccaacgacgtctatctccagatagggcttctcaccaccgtgggcctgtcg
acgaagaacgccatcctgatcatccagttcatcaaggaccagatgcaccaggggcatgaa
ctggtggaggcgaccctgacggcggtgaagatccgattgcggccggtcatcatgacctca
ctggccttcttcttcggcaccctgccgctggcactcaccaagggggccggggccgcggcc
cagaacgccatcggcaccgccgtgaccggggggctgctttcggctaccttcatcgacttg
atcttcatcccgttcttcttcgtgatggtgtcgaaggtgtttgccaagaaaaagcagcct
tccgttcagccggccgctgaagcagcgtcggaggtgaattga

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