Globicephala melas (long-finned pilot whale): 115843746
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Entry
115843746 CDS
T11080
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf01524
Platinum drug resistance
gmf03440
Homologous recombination
gmf03460
Fanconi anemia pathway
gmf04120
Ubiquitin mediated proteolysis
gmf04151
PI3K-Akt signaling pathway
gmf05206
MicroRNAs in cancer
gmf05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
115843746 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
115843746 (BRCA1)
03460 Fanconi anemia pathway
115843746 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
115843746 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
115843746 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
115843746 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
115843746 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
gmf01009
]
115843746 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
gmf04121
]
115843746 (BRCA1)
03036 Chromosome and associated proteins [BR:
gmf03036
]
115843746 (BRCA1)
03400 DNA repair and recombination proteins [BR:
gmf03400
]
115843746 (BRCA1)
Enzymes [BR:
gmf01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
115843746 (BRCA1)
Protein phosphatases and associated proteins [BR:
gmf01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
115843746 (BRCA1)
Ubiquitin system [BR:
gmf04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
115843746 (BRCA1)
Multi subunit type E3
BRCC complex
115843746 (BRCA1)
Chromosome and associated proteins [BR:
gmf03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
115843746 (BRCA1)
DNA repair and recombination proteins [BR:
gmf03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
115843746 (BRCA1)
BRCA1-A complex
115843746 (BRCA1)
BRCA1-B complex
115843746 (BRCA1)
BRCA1-C complex
115843746 (BRCA1)
BRCA complex
115843746 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
115843746 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-RING_6
zf-ANAPC11
zf-Nse
zf-RING_10
zf-rbx1
Motif
Other DBs
NCBI-GeneID:
115843746
NCBI-ProteinID:
XP_030695963
LinkDB
All DBs
Position
20:39658675..39722718
Genome browser
AA seq
1862 aa
AA seq
DB search
MDFSANHVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNHITKRSLQESTRFSQLVEELLKIIHAFELDTGLQIANSYNFSKKENNSSEHLKE
EVSIIQSMGYRNRAKKLQQSEPENPTLQETSLSVQLSNLGIVRSLRTKQQIQPQNKSVYI
ELGSDSSEDTVNEASYFSVGDHELLEITPQGAKAEASLNRAKKAACEFSEKDITKAEHHQ
FSNKDLTTTEKHETEKHPEKYQGIFVSNLHVEPCGTDTHASSLQHENSSLLLTKDRMNVE
KAEFCNKSKQLVLGKSQQSRWAESKDTCNDRQTPSTEKKVVLNADPLYGRKELNKQKPAS
SDSPRDSQEFPWITLNSSIQRVNEWFSRSDEMLTSYDSRDGAFESNTEVARAVEVPKEVD
GYLGSSEKIDLMASDPHGALIHERVHSKPVESNIEDKIFGKTYQRKTSLPNLSRIAEDLI
IGASTVEPQITQERPLTKKLKRKRRSTSGLHPEDFIKKVDLAVLPKTPEKIIEGTDQTEQ
NGHGINITSNGHETEMKGGYVQKEKNANLTESLEKESAFRTKAEPISSSISNMELELNIH
SSEAPKNRLRRKSSTRNIHALELAVSRNPSPPNHAELQIDSCSSSEEMKKKHSSQMPVRH
GKKLQFMGDKEPTTGAKKSDKPHKQITKRLASDTYPELNLTNIPVFFTHCSGSNKLQEFV
NPSLQREESLGTIQVSNNTKDPKDLTLSRGKGLQIERAVESTSISLVPDTDYGTQDSISL
LEADTLGKAKTAPNQHVSLCAAIESPKELIPGCSKDIRNDTEDFQDPLGHDVNHIQKASI
EMEESELDTQYLQNMFKVSKRQTFALFSNPEKECATVCAHSGSLREQSPRVPLECRQKEE
DQGKSESKIKHMQAINTTVDFPVAGQKDKKPSDHAKRSPERVTRLCQSSQFRGNKTELII
ANKHGISHNPYLIPSLSPIRSSVKTICKKNLSEEKFEEPVMSPERAMENESIVQSTVRTI
SQNNSRESTFKEVNSSSINEVGSSTNEVGSSINEVGSSGENIQAKLDRNRGPKLSASLRL
GLMQPEVYKQSLPVSNCQLPEIKRQGENEGTLQAVNEDFSPCLNPDNLEQPMGRSHASQV
CSETPDELLNDDKIKESNFAESDIEERSAVFSKSVQKGEFRRSPGPLAHHTSLVQGHERG
AESSEENVSSEDEELPCFQHLFGKVTNTLSPSTRHNAVATEGLSKETEENLISLKNSLND
CSDHVTSAKASEEHHLHEEARCSDSLFSSRCSAVEDLTANTNTQDPFLMFDPLSKQVGHQ
SYNQEVLSDKELVSDDDERETGWEEDNHQEEQSVDSDLGEAASEYESETSLSEDCLGLSS
QSDILTTQQRDTMQDNLLKIQQEMAELEAVLEQHGSQPSHSSPSLIADSCASEDLLNLEQ
NTSEKAVLTSEKSSEYPISQNPESLSADKFQVSPDTSTSKNKEPGMERSSPSKSQLSDNS
WYMHSHSRSLQSRNCPPQKELEVVDVEEQQLTESEAQDLMEQSSLPRQDLEGTPYLESGI
SLFSDDPESDPSEDRAPEPAHVCSMPPSASALKLPQFQAEESARSPAAAHITNTAGYNVR
EESVSREKPELIPSTQRGNKRISMVASGLTSKEFVLVHKFARKHHITLTNLITEETTHVI
MKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLDEHDFEVRGDVVNGRNHQG
PKRARESQDRKIFKGLEICCYGPFTNMPTDQLEWMVHLCGASVVKEPSSFTLSQGTQPIV
VVQPDAWTEGGGFHVIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQVPRAAADSSLP
CI
NT seq
5589 nt
NT seq
+upstream
nt +downstream
nt
atggatttttctgcgaatcacgttgaagaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagagcctgtttccacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatcatataaccaaaagaagcctacaagaaagtacaagatttagt
cagcttgttgaagagctattgaagatcattcatgcttttgagcttgacacaggattgcag
attgcaaacagttataacttttcaaaaaaggaaaataactcttctgaacatctaaaggag
gaagtttctatcattcaaagtatgggctaccgaaaccgggccaaaaaacttcaacagagt
gaacctgaaaatcctaccttgcaggaaaccagtcttagtgtccagctctctaaccttgga
attgtgagatctctgaggacaaagcagcagatacaacctcagaataagtccgtctacatt
gaattgggatctgattcttctgaagatacagttaatgaggccagttatttcagtgtagga
gaccatgaattgttagaaatcacccctcaaggagccaaggctgaagccagtttgaatcgt
gcaaaaaaggctgcttgtgagttttctgagaaggacataacaaaggctgaacatcatcaa
ttcagtaataaagatttgaccaccactgagaagcatgaaactgagaagcatccagaaaag
tatcagggtatttttgtttcaaacttgcatgtggagccatgtggcacagatactcatgcc
agctcattacagcatgaaaacagcagtttattactcactaaagacagaatgaatgtagaa
aaggctgaattctgtaataaaagcaaacagcttgtcttaggaaagagccaacagagcaga
tgggctgaaagtaaggacacatgtaatgataggcagactcccagtacagagaaaaaggta
gttctgaatgctgatcccctatatgggagaaaagaactgaataagcagaaacctgcctcc
tctgacagtcctagagattcccaagagtttccttggataacactgaatagcagcatacag
agagttaatgaatggttttccagaagtgacgaaatgctaacttcttacgactcacgtgat
ggggcatttgaatcaaacactgaagtagctcgtgcagtggaagttccaaaggaagttgat
ggatatttgggttcttcagagaaaatagacttaatggccagtgatcctcatggtgcttta
atacatgaaagagtccactccaaaccagtagagagtaatattgaagataaaatatttggg
aaaacctatcagaggaagacaagcctccctaacttgagccgcatagctgaagatctaatt
ataggagcatctactgtagaacctcagataacacaagagcgccccctcacaaaaaaacta
aagcgtaaaaggagaagtacatcaggccttcatcctgaggattttatcaagaaagtcgat
ttggcagttcttccaaagactcctgaaaaaataattgagggaactgaccaaacagagcag
aatggtcatgggataaatattactagtaatggtcatgagactgaaatgaaaggtggttat
gttcagaaagagaaaaatgctaacctaacagaatcattggaaaaagaatctgctttcaga
actaaggctgaacctataagcagcagtataagcaatatggaactagaattgaatatccat
agttcagaagcacctaaaaataggctgaggaggaagtcctctaccaggaacattcatgca
cttgaactagcagtcagtagaaacccaagcccacctaatcatgctgaactacaaattgat
agttgttctagcagtgaagagatgaagaaaaaacattccagccaaatgccagtcaggcac
ggcaaaaagcttcaattcatgggagataaagaacctacaactggagccaagaagagtgac
aagccacacaaacaaataactaagagacttgccagtgacacttacccagaactaaattta
acaaacatacctgttttttttactcactgttctggttctaataaacttcaagagtttgtt
aatcctagccttcaaagagaggagagcctaggaacaattcaagtgtcaaataataccaaa
gaccccaaagatctgacattaagtagaggaaaaggtttgcaaattgaaagagctgtagag
agtaccagtatttccttggtacctgatactgattatggcactcaggatagtatctcatta
ctggaagctgacaccctagggaaggcaaagacagcaccaaatcaacatgtgagtctgtgt
gcagcaattgaaagccccaaggaacttatccctggttgttctaaagatattagaaacgac
acagaggactttcaggatccactgggacatgacgttaaccacattcagaaggcgagcata
gaaatggaagagagtgaacttgatacacagtatttgcagaatatgttcaaggtttcaaag
cgtcagacgtttgctctgttttcaaatccagaaaaggaatgtgcaacagtctgtgcccac
tctgggtccttaagggaacaaagtccaagagtccctcttgaatgcagacaaaaagaagaa
gatcagggaaagagtgagtctaaaatcaagcatatgcaggcaattaatacaactgtggac
ttccctgtcgctggtcaaaaagataagaagccgagcgatcatgccaaacgtagcccagaa
agagtaactaggctttgtcagtcatcacagttcagaggcaacaaaactgagctcattatt
gcaaataaacatgggatttcacacaacccatatcttataccatcactttctcccatcagg
tcatctgttaaaactatatgtaagaaaaacctgtcagaggaaaagtttgaggaacctgta
atgtcacctgaaagagcaatggaaaacgagagcatcgttcaaagtacagtacgcacaatt
agccaaaataacagtcgagaaagcacttttaaagaagtcaactcaagcagtattaatgaa
gtaggttccagtactaatgaagtaggctctagtattaatgaagtaggttccagtggtgaa
aacattcaagcaaaactagatagaaacagaggacctaaattaagtgcttcgctcagatta
ggtcttatgcaacccgaagtctataagcaaagtcttcctgtaagtaactgtcaacttcct
gaaataaaaaggcaaggagaaaatgaaggcacacttcaggctgttaatgaagatttctcc
ccatgtctaaatccagataacctagaacaacctatgggaagaagccatgcttctcaggtt
tgttctgagacacctgatgagttgttaaatgatgacaaaataaaggaaagcaactttgct
gaaagtgacattgaggaaagatctgctgtttttagcaaaagtgtccaaaaaggagaattc
agaaggagccctggccctttagcccatcatacatctttggttcagggtcacgaaagaggg
gctgagtcctcagaagagaatgtgtctagtgaggatgaagagcttccttgcttccaacac
ttatttggtaaagtaaccaatacactgtctccatctaccagacataatgctgttgccaca
gagggtctatctaaggaaacagaggagaacctaatatcattgaagaatagtttaaatgac
tgtagtgaccacgtaacatcggcaaaggcatccgaggaacatcaccttcatgaggaagcg
agatgttctgatagcttattttcttcacggtgcagtgcagtggaagacttgaccgctaat
acaaacacccaggatcctttcttgatgtttgatcctctttccaaacaagtggggcatcag
tcttacaaccaggaagttctgagtgacaaggaattggtttcagatgatgacgaaagggaa
actggctgggaagaggataatcaccaagaagagcagagtgtggattcagacttaggtgaa
gcagcatccgagtatgagagtgaaacaagcctctctgaagactgtttggggctgtcctct
cagagcgatatcttaaccactcagcagagggataccatgcaagataacctgctaaagatc
cagcaggaaatggccgaactggaagctgtgttagagcagcacgggagccagccttctcac
agctccccttccctcatagccgattcttgtgcctctgaggacctgctaaatctggaacaa
aacacatcagaaaaagcagtattaacttcagagaaaagtagtgaatatcctataagccag
aatccagaaagcctttctgctgacaagtttcaagtatctccggatacttccaccagtaaa
aataaagaaccaggaatggaaaggtcttccccttctaaatcgcagttgtcagataatagt
tggtatatgcacagccactcaaggagtcttcagagcagaaactgcccacctcaaaaggag
cttgaggttgttgatgtggaggagcaacagctgacggagtctgaggcccaggatttaatg
gagcagtcttctttgccaagacaagatctagagggaaccccttacctagaatctggaatc
agcctcttctctgatgaccctgagtctgatccctctgaagacagagccccagagccagct
catgtctgcagcatgccaccctcagcctctgcactgaaattaccccaatttcaagcagaa
gaatctgccaggagtccggctgcagctcatattactaatactgcagggtataatgtgagg
gaagaaagtgtgagcagggagaagccagagttgataccttcaacacaaagaggcaacaaa
agaatttctatggtggcatcaggcttgacctcaaaagaatttgtgcttgtgcacaagttt
gccagaaaacatcacatcactttaactaatctaattactgaagagactactcatgtcatt
atgaaaacagatgctgagtttgtgtgtgaacggacactgaaatattttctgggaattgca
ggaggaaaatgggtagttagctatttctgggtgacccagtctattaaagaaagaaagatg
ctggatgagcatgattttgaagtcagaggcgatgttgtcaatggaagaaaccatcaaggc
ccaaagcgagcaagagaatcccaggacaggaagatcttcaagggcttagaaatctgttgc
tatggaccgtttaccaatatgcccacagatcaactagagtggatggtgcatctgtgtggg
gcttctgtggtgaaggagccctcatcattcaccctcagccagggtactcaaccaattgtg
gtcgtgcagccggatgcctggacagagggcggtggcttccatgtcatcgggcagatgtgt
gaagcacctgtggtgacccgagagtgggtattggacagcgtagccctctaccagtgccag
gagctggacacctacctgataccccaggtccccagagctgctgctgattccagcctgcca
tgtatatag
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integrated database retrieval system
