Globicephala melas (long-finned pilot whale): 115859481
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Entry
115859481 CDS
T11080
Symbol
PSEN2
Name
(RefSeq) presenilin-2 isoform X5
KO
K04522
presenilin 2 [EC:3.4.23.-]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf04330
Notch signaling pathway
gmf04722
Neurotrophin signaling pathway
gmf05010
Alzheimer disease
gmf05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
115859481 (PSEN2)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
115859481 (PSEN2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
115859481 (PSEN2)
05022 Pathways of neurodegeneration - multiple diseases
115859481 (PSEN2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
gmf01002
]
115859481 (PSEN2)
Peptidases and inhibitors [BR:
gmf01002
]
Aspartic peptidases
Family A22: presenilin family
115859481 (PSEN2)
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Gene cluster
GFIT
Motif
Pfam:
Presenilin
Tmemb_55A
Motif
Other DBs
NCBI-GeneID:
115859481
NCBI-ProteinID:
XP_030724335
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All DBs
Position
1:23606131..23633189
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AA seq
460 aa
AA seq
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MLTFMASDSEEEVCDERTSLMSAESPMPRSCQEGRQGLENGEGAAQWVGSHQQSKASGQR
GQESEEDHEEDPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMVVVVATIKS
VRFYTEKNGQLIYTPFTEDTSSVGQRFLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFI
HGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQ
QAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPI
FPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSCDSLGEPSYPEVFAPPLPGYP
GEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAV
FKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atgctcacattcatggcctctgacagcgaggaagaagtgtgtgacgagcggacgtccctg
atgtcagccgagagccccatgccgcgctcctgccaggaaggcaggcagggcctggagaac
ggagagggtgccgcccagtgggtaggttcccaccagcagtccaaggcctccggacagaga
ggccaggagagcgaggaggaccatgaggaggaccctgaccgctacgtctgcagcggggtc
cccgggcggccaccaggcctggaggaggagctgaccctcaaatacggggcaaagcacgtg
atcatgctgtttgtgcctgtcacgctgtgcatggtcgtggtggtggccaccatcaagtcc
gtgcgtttctacacggagaagaatggacagctcatctacacacctttcaccgaggacaca
tcttcggtgggccagcgcttcctcaactccgtgctcaacaccctcatcatgatcagcgtc
attgtcgtcatgaccatcttcctggtcgtgctctacaagtaccgctgctacaagttcatc
cacggctggctgatcatgtcctccctgatgctgctgttccttttcacctacatctacctt
ggggaagtgctcaagacctacaatgtggccatggactaccccaccctgttcctgaccgtc
tggaacttcggggcggtgggcatggtgtgcatccactggaagggccccttggtgctgcag
caggcctatctcatcatgatcagcgcgctcatggccttggtgttcatcaagtacctccca
gagtggtctgcgtgggtcatcctgggcgccatctctgtgtacgatctcgtggctgtgctg
tgccccaaagggccgctgagaatgctggtagaaactgcccaggagagaaacgagcccata
ttccctgccctgatatattcatccgccatggtgtggacagtgggcatggccaagttggac
ccctcctctcagggagcccttcagctcccctacgacccagagatggaagaggactcctgt
gacagtttgggggagccctcgtaccctgaagtctttgcgccccccctgcctggctacccg
ggggaggagctggaggaggaggaggaaaggggcgtgaagctcggcctcggagacttcatc
ttctacagcgtgctggtgggcaaggcggcagccacgggcagtggggactggaacaccacg
ctggcctgctttgtggccatcctcatcggtttgtgtctgacccttctgctgctcgccgtg
ttcaagaaagcgttgcccgccctccccatctccatcacgttcgggctaatcttctacttc
tccacagacaacctggtacggcctttcatggacaccctggcctcccatcagctctacatc
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