Globicephala melas (long-finned pilot whale): 115863277
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Entry
115863277 CDS
T11080
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf01522
Endocrine resistance
gmf04012
ErbB signaling pathway
gmf04062
Chemokine signaling pathway
gmf04148
Efferocytosis
gmf04151
PI3K-Akt signaling pathway
gmf04360
Axon guidance
gmf04370
VEGF signaling pathway
gmf04510
Focal adhesion
gmf04670
Leukocyte transendothelial migration
gmf04810
Regulation of actin cytoskeleton
gmf04935
Growth hormone synthesis, secretion and action
gmf05100
Bacterial invasion of epithelial cells
gmf05135
Yersinia infection
gmf05146
Amoebiasis
gmf05163
Human cytomegalovirus infection
gmf05165
Human papillomavirus infection
gmf05170
Human immunodeficiency virus 1 infection
gmf05200
Pathways in cancer
gmf05202
Transcriptional misregulation in cancer
gmf05205
Proteoglycans in cancer
gmf05208
Chemical carcinogenesis - reactive oxygen species
gmf05222
Small cell lung cancer
gmf05417
Lipid and atherosclerosis
gmf05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
115863277 (PTK2)
04370 VEGF signaling pathway
115863277 (PTK2)
04151 PI3K-Akt signaling pathway
115863277 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
115863277 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
115863277 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
115863277 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
115863277 (PTK2)
04062 Chemokine signaling pathway
115863277 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
115863277 (PTK2)
09158 Development and regeneration
04360 Axon guidance
115863277 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
115863277 (PTK2)
05202 Transcriptional misregulation in cancer
115863277 (PTK2)
05205 Proteoglycans in cancer
115863277 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
115863277 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
115863277 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
115863277 (PTK2)
05163 Human cytomegalovirus infection
115863277 (PTK2)
05165 Human papillomavirus infection
115863277 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
115863277 (PTK2)
05100 Bacterial invasion of epithelial cells
115863277 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
115863277 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
115863277 (PTK2)
05418 Fluid shear stress and atherosclerosis
115863277 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
115863277 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gmf01001
]
115863277 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
gmf01009
]
115863277 (PTK2)
Enzymes [BR:
gmf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
115863277 (PTK2)
Protein kinases [BR:
gmf01001
]
Non-receptor tyrosine kinases
FAK family
115863277 (PTK2)
Protein phosphatases and associated proteins [BR:
gmf01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
115863277 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_C_FAK1
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
115863277
NCBI-ProteinID:
XP_060143120
LinkDB
All DBs
Position
17:complement(77070890..77325200)
Genome browser
AA seq
1137 aa
AA seq
DB search
MLLEVTGRGALGPTGAVCMEKSGCSPFPVCWAKEYDRYLASSQIMAAAYLDPNLNHTPNS
STKTHLGTGVERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMLEIADQVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGTL
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVHGATQSFIIRPQKEGERALPSIPKL
ANSEKQGVRTHAVSVSGVSHCQHKVKKARRFLPLVFCSHEPPSADEISGDETDDYAEIID
EEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGAYTSPENPALAVAIKT
CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK
YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST
YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI
ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRMES
RRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFHPSPQHMVQTNHYQVSGYPGSHGITA
VAGSIYPGQASLLDQTDSWNHRPQEIPMWQPNVEDSATLDLRGIGQVLPTHLMEERLIRQ
QQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGGPQGPTGNQHIYQPVGKPDPAAPPKK
PPRPGAPGHLSSLASLGSPGDNYNEGVKLQPQEISPPPTANLDRSNDRVYENVTGLVRAV
IEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPVLPASTHREIEMAQKLLNSDLG
ELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKALGQTRPH
NT seq
3414 nt
NT seq
+upstream
nt +downstream
nt
atgttgttggaagtgacgggccgaggggccctgggacccacaggtgctgtctgtatggag
aagagcggctgtagtccatttccagtgtgttgggctaaagaatatgacagatacctagca
tctagccaaataatggcagctgcctaccttgacccaaacttgaatcacacaccgaattca
agtaccaagactcacctgggtaccggtgtggaacgttcccctggggccatggagcgagtg
ttgaaggtctttcattattttgaaagcaacagtgagccaaccacttgggccagtattatc
aggcatggagacgctactgacgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgcctcagtcacctgcggtcagaggaggttcac
tggctccatttggatatgggtgtctccaatgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagacaagccaactctgaatttcttctatcaacaggtgaagagcgattatatg
ttggagatcgctgatcaagtggaccaggacattgctttgaagttgggttgtctagaaata
cggcggtcgtactgggagatgcggggcaacgccctggagaagaagtctaactatgaagta
ttagaaaaagatgttggtttgaagcgattttttcctaggagtttactggactcagtcaag
gccaaaacactaagaaaattgattcagcaaacatttagacagtttgccaaccttaataga
gaagaaagtattttgaaattctttgagatcctctccccagtgtacagatttgataaagaa
tgcttcaagtgtgcccttggttcgagctggattatttcggtggagctggcgattggcccc
gaagaagggatcagttacctcacagacaagggctgcaaccccacacacctggccgacttc
aatcaagtgcagaccattcagtattcaaacagcgaagacaaggacaggaaagggacgctg
cagctgaagattgcaggagcgcctgagcctctgacggtgacagcaccgtccctgaccatt
gccgagaacatggccgacctgatagatgggtactgccggctggtgcacggggccacgcag
tctttcatcatcaggcctcagaaagaaggtgaacgggctttgccatcgataccaaagctg
gccaacagcgagaagcagggcgttcggacccacgccgtctctgtgtcaggagtcagtcac
tgccaacataaagttaagaaagctaggcgctttctccctttggtcttctgttcccacgaa
cctccttctgcggatgaaattagtggggacgaaacagatgactatgctgagattatcgac
gaggaagatacctacaccatgccctcgaaaagctatggaatagatgaagccagggactat
gagattcagagagaaagaatagaactgggacggtgcatcggagagggccagttcggagac
gtgcaccaaggcgcttacacgagcccggagaatccagctttggcggttgcaattaaaaca
tgtaaaaactgtacttcggacagcgtgagagagaaattccttcaagaagccttaacaatg
cgtcagtttgaccaccctcacattgtgaagctgatcggagtcatcacagagaaccccgtc
tggatcatcatggagctgtgcacgctcggagagctgaggtcatttctgcaagtaaggaaa
tacagtttggatctagcatctctgatcctctatgcctatcagcttagcacagcccttgcg
tacctagagagcaaaagatttgtgcacagggacattgctgctcggaatgttctggtgtcc
tcaaacgactgtgtaaaattaggagacttcggcttatcccgatacatggaagacagcact
tactacaaagcttccaaaggaaaattgcctattaaatggatggctccagagtcaatcaat
tttcgccgttttacctcagctagtgacgtatggatgtttggtgtgtgtatgtgggagata
ctgatgcacggtgtgaagccctttcaaggcgtgaagaacaatgatgtgattggtcgcatt
gagaacggggagaggttgcccatgcctccgaactgccctcccaccctctacagcctcatg
accaagtgctgggcctacgaccccagccggcggccccgcttcactgagctcaaagctcag
ctcagcacaatcctggaggaagagaaggtccagcaagaagaacggatgaggatggagtcc
agaaggcaggtcacagtgtcctgggactctggagggtccgacgaagcaccacccaagccc
agcagacctggttatcctagtccgaggtccagcgaagggtttcatcccagcccacagcac
atggtacagaccaatcactaccaggtctctggctaccctggctcacatggaatcacagcc
gtggctggcagcatctacccaggtcaggcatctcttttggaccaaacggattcgtggaat
cacagaccacaggagataccgatgtggcagcccaacgtggaggactctgcaacactggac
ctgcgtggcatcgggcaggtgttgccgacccacctgatggaggagcggctgatccggcag
cagcaggagatggaagaggaccagcgctggctggagaaggaggagaggtttctgaaacct
gacgtgcggctctctcgaggcagcatcgacagggaggatggaggtcctcagggcccgact
ggaaaccagcacatatatcagcctgtgggcaaaccagatcctgcagctccaccaaagaaa
ccaccgcgtcccggagcccctgggcacctgagcagcctcgccagcctcggcagccccggg
gacaattacaacgagggtgtcaagcttcagccccaggaaatcagcccccctcccactgcc
aacctggaccggtccaatgacagggtgtacgagaacgtgacgggcctggtgagagcggtc
atcgagatgtccagcaagatccagccagccccgccagaggagtatgtccccatggtgaag
gaagtcggcttggccctgaggacgctgttggccaccgtggatgagaccattcccgtcctg
cccgccagcacccaccgagagattgagatggcccagaagctgctgaactccgacttgggg
gagctcatcaacaagatgaagctggcccagcagtatgtcatgaccagcctgcagcaggag
tacaagaagcagatgctgacggccgcacacgccctggccgtggacgccaagaacctgctc
gatgtcatcgaccaggccagactgaaggccctggggcagacgaggccacactga
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