Globicephala melas (long-finned pilot whale): 115864151
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Entry
115864151 CDS
T11080
Symbol
HK2
Name
(RefSeq) hexokinase-2
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf00010
Glycolysis / Gluconeogenesis
gmf00051
Fructose and mannose metabolism
gmf00052
Galactose metabolism
gmf00500
Starch and sucrose metabolism
gmf00520
Amino sugar and nucleotide sugar metabolism
gmf00524
Neomycin, kanamycin and gentamicin biosynthesis
gmf01100
Metabolic pathways
gmf01200
Carbon metabolism
gmf01250
Biosynthesis of nucleotide sugars
gmf04066
HIF-1 signaling pathway
gmf04910
Insulin signaling pathway
gmf04930
Type II diabetes mellitus
gmf04973
Carbohydrate digestion and absorption
gmf05230
Central carbon metabolism in cancer
Module
gmf_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
gmf_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
115864151 (HK2)
00051 Fructose and mannose metabolism
115864151 (HK2)
00052 Galactose metabolism
115864151 (HK2)
00500 Starch and sucrose metabolism
115864151 (HK2)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
115864151 (HK2)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
115864151 (HK2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
115864151 (HK2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
115864151 (HK2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
115864151 (HK2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
115864151 (HK2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
115864151 (HK2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
gmf04131
]
115864151 (HK2)
Enzymes [BR:
gmf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
115864151 (HK2)
Membrane trafficking [BR:
gmf04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
115864151 (HK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
FGGY_N
Motif
Other DBs
NCBI-GeneID:
115864151
NCBI-ProteinID:
XP_030733540
LinkDB
All DBs
Position
12:complement(25707103..25768559)
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AA seq
917 aa
AA seq
DB search
MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEIAKRFRKEMEKGLGATTHPTAS
VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMR
GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCLQTKLDESFLVSWTKGFKSSGV
EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME
EMRHIDMVEGDEGRMCINMEWGAFGDDGVLDDIRTEFDQEIDMGSLNPGKQLFEKMISGM
YMGELVRLILVKMAKEELLFGGKLSPELLATGHFETKDVSDIEGEKDGIRKAREILVRLG
LDPTQEDCVATHRVCQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKH
PHFAKRLHKTVRRLVPDCDIRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLS
REQLLEVKRRMKVEMERGLSKETHTIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV
LLVRVRNGKRRGVEMHNKIYSIPREVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF
TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG
TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD
FRTEFDAAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKHGLLFRGRISERLKTRG
IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA
VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG
AALITAVACRIREAGQR
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcctcgcatctgctcgcctacttctttacggagctcaaccatgaccaagtgcag
aaggttgaccagtatctctaccacatgcgtctttctgatgagaccctcctggagattgct
aagcggttccgcaaggagatggagaaagggcttggagctaccacccaccccactgcttca
gtaaaaatgctgcctacctttgtgaggtctactccagatgggacagaacatggagaattc
ctggctctggaccttggagggaccaacttccgtgtgctttgggtgaaagtaacagacaat
gggctccagaaggttgagatggagaaccagatctacgccattcccgaggacatcatgcga
ggcagtggcacccagctgtttgaccacattgctgaatgcctggccaacttcatggataag
ctacaaatcaaagacaagaagctcccgttgggttttaccttctcattcccctgtctccaa
acaaaactagacgagagtttcctggtctcatggaccaaggggttcaagtccagtggtgtg
gaagggaaagatgtggttactctgatccggaaagccatccagaggagaggggactttgat
attgacattgtggcagtggtgaatgacacagttgggaccatgatgacctgtggttatgat
gaccagaactgcgagattggtctcattgtgggcacgggcagcaatgcttgctacatggaa
gagatgcgccacatcgacatggtggagggtgatgagggccgtatgtgtatcaacatggag
tggggagcctttggggatgatggcgtgcttgatgacatccgcacggagtttgaccaggag
atcgacatgggctctctgaaccccgggaagcaactatttgagaagatgatcagtggaatg
tacatgggggagctcgtgaggcttatcctagtgaagatggccaaggaggagctgcttttc
ggggggaagctcagccctgaactcctcgccacgggccactttgagaccaaagatgtttca
gatattgaaggggagaaggatggcatccggaaggcccgtgagatcctggtgcggctgggc
ctggacccgacacaggaggactgtgtggccactcaccgggtctgccagatcgtgtccaca
cgctcagccagcctgtgcgcggctacgctggcagccgtcctgcggcgcatcaaggagaac
aagggcgaggagcggctgcgctccaccatcggggtggacggttctgtctacaagaagcat
ccccatttcgccaagcgtcttcacaagaccgtgcggcgcctggtgcccgactgcgacatc
cggttcctccgctctgaggacggcagtggcaagggggcagccatggtgacagcagtggcc
taccggctggccgatcaacaccgagcccgccagaagaccctggagtctctgaagctgagc
cgtgagcagctgctggaggtcaagaggaggatgaaggtagaaatggagcgaggtctgagc
aaggagactcacaccattgcccccgtcaagatgctgcccacctatgtgtgtgccacccct
gatggcacagagaaaggtgacttcctggccttggaccttgggggtaccaatttccgggtc
ctgctggtgcgcgtgcggaatgggaagcgacgtggagtggagatgcacaacaagatctac
tctatcccgcgggaggtcatgcatggcacaggggatgagctctttgaccacatcgtccag
tgcattgccgacttccttgagtacatgggcatgaagggcgtgtccctgcctctgggtttc
accttctccttcccctgccagcagaacagcctggacgagagcatcctcctcaagtggact
aaaggcttcaaggcatctggctgcgagggtgaggacgtggttacactgctgaaggaagcc
atccaccggcgagaggagtttgacctggatgtggttgctgtggtgaatgacacagttggg
actatgatgacctgtggctatgaagaccctcactgtgaagttggcctcattgttggcacg
ggcagcaatgcctgctacatggaggagatgcggaatgttgagctggtggaaggggaagag
gggcggatgtgtgtcaacatggagtggggggccttcggggacaatggatgcctagatgac
ttccgcacagaatttgatgcagctgtggatgaactttccctcaaccctggcaaacagagg
ttcgagaaaatgatcagtggcatgtacttgggcgaaattgttcgtaacatcctcatcgat
ttcaccaaacatgggctgctcttccgtggccgcatctcggagcggctcaagacacgggga
atctttgaaaccaagttcctgtctcagattgagagtgactgcctggccctgctgcaggtc
cgtgccatcctgcaccacttagggcttgagagcacctgtgatgacagcatcattgtcaag
gaggtgtgcactgtggtggcgcggcgggcagcccaactctgtggtgcaggcatggccgcc
gtggtggacaaaatacgagagaaccgtgggctggacaccctcaaagtgacagtgggcgtg
gatgggaccctctacaagctacatcctcactttgccaaagtcatgcatgagacggtgaag
gacttggctccaaaatgtgatgtgtccttcctggagtcggaggatggcagcgggaagggg
gcggctctcatcactgctgtggcctgccgcatccgagaggctggacagcggtag
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