Globicephala melas (long-finned pilot whale): 115865389
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Entry
115865389 CDS
T11080
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf04062
Chemokine signaling pathway
gmf04151
PI3K-Akt signaling pathway
gmf04217
Necroptosis
gmf04550
Signaling pathways regulating pluripotency of stem cells
gmf04630
JAK-STAT signaling pathway
gmf04658
Th1 and Th2 cell differentiation
gmf04659
Th17 cell differentiation
gmf05161
Hepatitis B
gmf05162
Measles
gmf05166
Human T-cell leukemia virus 1 infection
gmf05169
Epstein-Barr virus infection
gmf05200
Pathways in cancer
gmf05203
Viral carcinogenesis
gmf05223
Non-small cell lung cancer
gmf05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
115865389 (JAK3)
04151 PI3K-Akt signaling pathway
115865389 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
115865389 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
115865389 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
115865389 (JAK3)
04659 Th17 cell differentiation
115865389 (JAK3)
04062 Chemokine signaling pathway
115865389 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
115865389 (JAK3)
05203 Viral carcinogenesis
115865389 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
115865389 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
115865389 (JAK3)
05161 Hepatitis B
115865389 (JAK3)
05162 Measles
115865389 (JAK3)
05169 Epstein-Barr virus infection
115865389 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
115865389 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gmf01001
]
115865389 (JAK3)
Enzymes [BR:
gmf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
115865389 (JAK3)
Protein kinases [BR:
gmf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
115865389 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
ABC1
FERM_C_FAK1
SH2
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
115865389
NCBI-ProteinID:
XP_030736021
LinkDB
All DBs
Position
3:complement(159324418..159340254)
Genome browser
AA seq
1104 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQCLSFSFGDHSAEELCVWAAKA
SGILPVYHSLFALALEDLSCWFPPSHIFSVEDAGTQVLVYRLRFYFPNWFGLEKVHRFGL
RKDVASAILDLPVLEHLFAQHRNDLVSGRLPMGLSLKEQGECLSLAVLDLAQMALEQGQR
PEELLKTISYKVCLPPGLRDLIQGLNFVTRRRIRRTVRRALRRLAACQADKHSLMAKYIM
DLERLDPDRATETFRVALPGAAGGQDAPGQLRVAGGSGIAWSPGEHEVLQPFCDFPEIVD
ISIKQAPRFGPAGEHRLVTITRTDNQILEAEFPGLPAALSFVALVDGYFRLTTDSGHYFC
KEVAPPRLLEQVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSYLLTVCVPTP
LGPDYKGCLIRCDPTGTFSLAGLGQPHSSLRELLAAYWGGGLHVDGVELNLTFCCTPRPK
EKSNLIVVRRDCNPPTSSPVQPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR
HEVVDGEARETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ
EFVYLGALDTYLRKCGQLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA
DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS
GVTMPISTLDPAKKLQFYQERQQLPAPKWMELALLIQQCMAYEPGQRPSFRAVIRDLNSL
ITSDYELLSDPTPGALAPHDGLWNSAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPEQQKDFQREIQILKALHSDFIVKYRGVSYGPGRLSLRL
VMEYLPSGCLRDFLQRHRARLDAGRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE
THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYSDKSCSPSAEFLRMMGCERDVPALCRLLELLADGQRLPAPPACPGEVHELMKLCWAP
SPQDRPPFSALGPQLDALWSGSQG
NT seq
3315 nt
NT seq
+upstream
nt +downstream
nt
atggcacctccaagtgaggagacgcccctgatccctcagcgctcctgcagcctctcctct
tcagaggctggtgccctgcacgtgctgctgcccccgcggggccctggacccccacagtgc
ctatccttctcctttggggaccactcagctgaagagctatgtgtttgggctgctaaggcc
agtggcatcctgcccgtgtaccactccctctttgctctggccttggaggacctgtcctgt
tggttccccccgagccacatcttctccgtggaggacgcgggcacccaggtccttgtctac
aggctccgcttttacttccccaactggtttgggctagagaaggtccaccgctttgggcta
cgaaaggacgtagccagtgccatccttgacctgccagtcctggagcacctctttgcccag
caccgcaatgacctggtcagcggccgcctcccgatgggcctcagcctcaaggagcagggt
gagtgtctcagcttggctgtgctggacctggcccagatggccctcgagcagggtcagcgg
cccgaggagctgctgaagaccatcagctacaaggtctgcctgcccccgggcctgcgcgac
ctgatccagggcctgaacttcgtgacgcggaggcgtatccgaaggacagtgcgccgggcc
ttgcgccgcttggccgcctgccaggctgataagcactcgctcatggccaagtacatcatg
gatctcgagcggctggacccagacagggccaccgagaccttccgcgtggccctccccgga
gctgctggtggtcaggatgcgccggggcagctccgcgtggctggcggcagtggcatcgcc
tggagcccgggagaacacgaggtcctccagcccttctgcgactttccagaaatcgtggat
atcagcatcaagcaggccccacgctttggccccgccggggagcaccgcctggtcaccatc
accaggacagacaaccagatcctggaggccgagttcccggggctgcccgcagcgttgtcc
ttcgtggcgctcgtggatggctacttccggctgaccactgactccgggcactacttctgc
aaggaggtggcgccgccgcggctgctggagcaggtggctgagcagtgccatggccccatc
accttggattttgccatcaacaaactcaagactgggggttcacttcccggctcctacgtt
ctccgccgcagtccccaggatttcgacagctacctcctaactgtctgtgtcccgaccccc
ctgggccctgattacaagggctgcctcatccggtgcgaccccacaggaaccttctccctg
gctggccttggccagccccacagcagtcttcgagagctcctggcagcctattggggtggt
gggttgcacgtggatggggttgagctgaacctcaccttctgctgcacccccagacccaaa
gaaaagtccaatctgattgtggtccggagagattgcaacccacccacatcatcccctgtt
cagccccaatcccaatgccagctgagtcagatgacatttcacaagatccctgctgacagc
ctggagtggcatgagaacctgggtcacgggtcctttaccaagatttaccggggctgtcgc
catgaggttgtggatggggaggcccgagagacagaggtgctgctcaaagtgatggatgcc
aagcacaagaactgcatggagtcattcctggaagcagcgtccttgatgagccaagtgtcg
taccagcatctcgtgttgctccatggcgtgtgcatggctggagacagcataatggtgcag
gaatttgtatacctgggagcgctggacacatatctgcgcaagtgtggccagctggtgccg
gccagctggaaactacaggtgatcaaacagctggcttatgccctcaactatctggaagac
aaaggtctccctcacggcaatgtctcagcccggaaggtgctcctggctcgggagggggct
gacgggaacctgcctttcatcaagctgagtgaccccggtgtcagccccactgtgctaagc
ctggagatgctcactgacaggatcccctgggtggcccctgagtgtctccaggaggcccga
acacttggcttggaagctgacaagtggggatttggtgccacagtctgggaggtgttcagc
ggtgtcacaatgcccatcagcaccctggatcctgccaagaagctccagttttaccaggaa
cggcagcaactgcctgcacccaagtggatggagctggccctgctgatccaacagtgcatg
gcctacgagccaggccagaggccctctttccgcgctgtcatccgtgacctgaacagcctc
atcacttcagattatgagctcctctcagaccccacacctggtgccctggctccccatgat
gggctttggaatagcgcccagctctatgcctgccaggaccctaccatctttgaggagaga
cacctcaagtacatctcacagctgggcaagggcaactttggcagcgtggaactgtgccgc
tatgacccgctgggcgacaacacaggcgccctggtggccgtgaagcagttgcagcacagc
gggccagaacagcagaaggacttccagcgggagatccagatcctcaaagccctgcacagt
gacttcattgtcaagtaccggggtgtcagctatggcccaggccgcctgagcctgcggctg
gtcatggagtacctgcccagcggctgcctgcgcgacttcctgcagcggcaccgcgcgcgc
cttgacgctggccgcctgctcctctacgcctcgcaaatctgcaagggcatggagtacctg
ggctcccgccgctgcgtgcaccgcgacctggcagcccgtaacatcctggtggagagcgag
acgcatgtcaaaatcgctgacttcggcctcgccaagctgctgccgctcgacaaagactac
tacgtggtccgcgagccaggccagagccccatcttctggtacgccccagagtccctctcg
gacaacatcttctcgcgccagtcggatgtctggagcttcggggtcgtcctgtacgagctc
ttcacctacagtgacaagagctgtagcccctcagccgagttcctgcggatgatgggatgt
gagagagatgtgccagccctctgccgcctcctggagctgctggccgacggccagaggctg
cccgcacctcctgcctgtcctggtgaggttcatgagctcatgaagctgtgctgggcccct
agcccacaagaccggccaccattcagcgccctgggcccccagctggatgcactgtggagt
ggaagccagggatag
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