Garra rufa (doctor fish): 141347044 Help Entry 141347044         CDS       T11039                                  Symbol casp8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism grf  Garra rufa (doctor fish) Pathway grf04115   p53 signaling pathway grf04210   Apoptosis grf04217   Necroptosis grf04620   Toll-like receptor signaling pathway grf04621   NOD-like receptor signaling pathway grf04622   RIG-I-like receptor signaling pathway grf04623   Cytosolic DNA-sensing pathway grf04625   C-type lectin receptor signaling pathway grf05132   Salmonella infection grf05168   Herpes simplex virus 1 infection Brite KEGG Orthology (KO) [BR:grf00001]  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     141347044 (casp8)    04217 Necroptosis     141347044 (casp8)    04115 p53 signaling pathway     141347044 (casp8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     141347044 (casp8)    04621 NOD-like receptor signaling pathway     141347044 (casp8)    04622 RIG-I-like receptor signaling pathway     141347044 (casp8)    04623 Cytosolic DNA-sensing pathway     141347044 (casp8)    04625 C-type lectin receptor signaling pathway     141347044 (casp8)  09160 Human Diseases   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     141347044 (casp8)   09171 Infectious disease: bacterial    05132 Salmonella infection     141347044 (casp8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:grf01002]     141347044 (casp8) Enzymes [BR:grf01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      141347044 (casp8) Peptidases and inhibitors [BR:grf01002]  Cysteine peptidases   Family C14: caspase family    141347044 (casp8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED Motif Other DBs NCBI-GeneID:  141347044 NCBI-ProteinID:  XP_073708119 LinkDB All DBs Position 12:12552234..12560977 Genome browser AA seq 470 aa AA seqDB search MDLQKFHEIDENLTSSEVAQLKFLCVDLIPKKRLETVNDAKELFMRLDEQTLLDDRLLVP ELLTTIGRLDLLGILDMTKEDVERNLLQRDASSKGVSAYRKMLFGISEDMTEENFHAVKF LVQLPKAKLGTSATFLDVMTEMEKLQKLGEDKLDELYNILDKCDKQLACRIQEYRAQQQG GRLPLRQVSLPDESMQRNVSMPNLWRRDSLVPDSDTEPISGEYYNITQRPLGHCLIINNY NFKETSSLSDRAGTNKDKDDLSRVFHRMHFKVKVHDDLTASNMKNVIKQFAESDHTRMGA FVCCVLSHGEKGTVLGVDGKEVEIRELTMPIAKCLTLLSKPKLFFIQACQGHEGQNGVWT SDAPEANPTEDDPYEDDAYNPALRSIPIEADMLIGMATVEHYLSFRHTRQGSVYIQELCH QLEKCCPRKEDILSVLTKVNREVSLKTLKGRKQMPEPRYTLTKKLVLPMD NT seq 1413 nt NT seq  +upstreamnt  +downstreamnt atggatcttcagaagtttcacgagattgatgagaacctgacgagcagtgaagtggcccag ctgaagttcctgtgcgtggacctaattcccaagaaacgtttggagacagtgaatgatgcc aaagaactcttcatgcgactggatgagcaaacactgcttgatgataggctactcgtccct gagctgctgaccacaattggccgccttgacttgcttggcattctggatatgaccaaagaa gatgtggaaagaaatctgctacaacgtgacgcgtctagtaaaggtgtctcagcctacaga aaaatgctatttggaatatctgaggacatgacagaagaaaactttcacgcagtgaagttc cttgtgcagcttccaaaagcaaaactaggaacgtctgctacatttctagatgtaatgact gagatggaaaagctacaaaagctaggggaagacaagctggatgaactttacaatattcta gacaaatgtgacaaacagctggcctgcaggatacaggagtacagggcccagcaacaagga ggcagacttcctctacggcaagtttccttacctgatgaaagtatgcaaagaaatgtaagt atgccaaatctttggaggagagactcacttgttcccgattcagacactgaacccatatcg ggagaatattacaatattactcagcggcctcttggacactgtctaatcattaacaactac aactttaaggaaacatcctcattgtccgatcgggccggcacgaacaaggacaaagatgac cttagcagagtgtttcacagaatgcatttcaaggttaaggttcatgatgatctgacagct tccaatatgaagaatgtgataaagcaatttgcagaaagcgatcatactcgaatgggtgct tttgtctgctgtgtcctttcgcatggagagaagggaacagtgttgggtgtagatggcaaa gaggttgaaatccgtgaactcaccatgcccattgctaaatgccttacattattatccaag cccaagcttttcttcattcaagcctgccaaggacatgagggccagaatggtgtatggaca tcagatgcaccagaagcaaaccccacagaggacgacccatatgaggatgatgcttataat cctgcgttacgctctattcctatagaagccgatatgctaattggaatggccacagtagag cactacctgtctttccgccacactagacaagggtctgtctatatccaggagctctgtcat cagttggagaaatgctgccccagaaaagaggatatcttgtccgtcctgacgaaggtaaac cgtgaagtcagcttgaaaacgttaaaaggccgcaagcagatgcctgaacctcgatatacc ctcaccaagaagctggtcctgcccatggactag

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