Garra rufa (doctor fish): 141348592
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Entry
141348592 CDS
T11039
Symbol
cad
Name
(RefSeq) multifunctional protein CAD isoform X1
KO
K11540
carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:
6.3.5.5
2.1.3.2
3.5.2.3
]
Organism
grf Garra rufa (doctor fish)
Pathway
grf00220
Arginine biosynthesis
grf00240
Pyrimidine metabolism
grf00250
Alanine, aspartate and glutamate metabolism
grf01100
Metabolic pathways
grf01240
Biosynthesis of cofactors
Module
grf_M00051
De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:
grf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
141348592 (cad)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
141348592 (cad)
00220 Arginine biosynthesis
141348592 (cad)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
grf01002
]
141348592 (cad)
Enzymes [BR:
grf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.2 aspartate carbamoyltransferase
141348592 (cad)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.2 In cyclic amides
3.5.2.3 dihydroorotase
141348592 (cad)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
141348592 (cad)
Peptidases and inhibitors [BR:
grf01002
]
Cysteine peptidases
Family C26: gamma-glutamyl hydrolase family
141348592 (cad)
Metallo peptidases
Family M38: beta-aspartyl dipeptidase family
141348592 (cad)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
GATase
CPSase_sm_chain
OTCace_N
OTCace
CPSase_L_D3
MGS
ATP-grasp
Dala_Dala_lig_C
ATPgrasp_Ter
Amidohydro_1
ATP-grasp_3
Peptidase_C26
RimK
DJ-1_PfpI
GSH-S_ATP
Motif
Other DBs
NCBI-GeneID:
141348592
NCBI-ProteinID:
XP_073708967
LinkDB
All DBs
Position
13:complement(34230933..34262558)
Genome browser
AA seq
2256 aa
AA seq
DB search
MLLKMASLVLEDGTTFKGRLFGAVSSVSGEVVFQTGMVGYPEALTDPSYKSQILTLTYPL
IGNYGIPEDEDGEFGLSKWFESSKIHASALIVGELSENPSHWSSAKSLDQWLREQGIPGL
EGVDTRSLTQKIREKGTMLGKLVVEGTSANDIPFDNPDNRNLIKEVSMKEPKVFNPEGTV
RITAVDCGIKYNQIRCLCQRGARVTVVPWDHPLDSNDFDGLFISNGPGNPEYCKETVENI
RKVACVENPKPVFGICLGHQLLSLVIGAKTYKMKYGNRGHNQPCIHKGTNRCFITSQNHG
FAVDPKTLPEDWDVLFTNANDQTSEGIVHNHKPLFSVQFHPEHMAGPTDLVGLFDVFLET
VKDAKEGKAGKSVKQRLTEHLTYPGSPDPEAFVRPRKVLVLGSGGLSIGQAGEFDYSGSQ
AIKALKEENIQTVLINPNIATVQTSKGLADKVYFLPITPEYVTQVIKNERPDGVLLTFGG
QTALNCGVELTKQGVLEKYKVRVLGTPVASIEMTEDRKIFVEKMEEINEHVAPSEAAMSV
EQAVAAAERLGYPVLVRSAFALGGLGSGFANNREEMITLVTQAFAHTSQVLVDKSLKGWK
EIEYEVVRDAYDNCITVCNMENVDPLGIHTGESIVVAPSQTLNDYEYNMLRNTAIKVIRH
LGIVGECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLGLGIPLPKL
KNSVTNSTTANFEPSLDYCVVKVPRWDLSKFLRVSTKIGSSMKSVGEVMAIGRSFEEAFQ
KALRMVDENCVGFDHTIKPVSEEELQTPTDKRIFVLAGALRAGYTVERLYELTKIDHWFL
HKMKNIADHEKLLEAYNKDESAMPPEVMRKAKQLGFSDKQIAQAVQSTELAVRKMRRDWK
ILPVVKQIDTVAAEWPAHTNYLYLTYHGSESDVIFKQPHVMVIGSGVYRIGSSVEFDWCA
VGCIMELRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYEMENPEGIILSM
GGQLPNNIAMSLHRQQCRILGTSPEFIDSAENRFKFSRMLDTIGISQPRWKELSDTESAV
GFCETVGYPCLVRPSYVLSGAAMNVAFSDTDLERFLSSAVALSKEHPVVISKFIQEAKEI
DVDAVACDGEVIAIAVSEHVENAGVHSGDATLVTPPQDINQKTMERIKIIVHAIGQELQV
TGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEDVGLMKG
NGIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPKKNI
LLSIGSYKNKSELLQTVQTLEVLGYNLYASLGTADFYTEHGVKVMAVDWPFEEESDCPNK
DKQRNIMDYLAENHFDLVINLSMRNSGGRRLSSFVTKGYRTRRMAIDYSVPLITDIKCTK
LFVQALRQIGQAPHVKTHVDSMTSQKLIRLPGLIDVHVHLREPGATHKEDFSSGTAAALA
GGITMVCSMPNTNPAIIDPSTFAMAQKLAKAGCRCDYALFVGASSDNATLLPSIASSAAG
LKMYLNDTYSTLKMDNVSLWMEHFEKWPKHLPIVAHAEKQTVAAILMVAQLYQRPVHICH
VAKKEEILIIRAAKQKGIQVTCEVAPHHLFLCDDNVSAIGNGRAQVRPMLGTREDMEALW
ENLDIIDCFATDHAPHSVEEKNSEKPPPGYPGLETMLPLLLTAVSDGRLTVDDIIKRLYE
NPSKIFSLPVQEDTYVEVDLEQEWTIPKHMQFTKSKWTPFGGMKVKGKVMRVVLRGEVAY
IDGQVLVPPGYGQDVRSWSPPPAVTTEVIKDAPKRLSETITPERPRQTAPADVVRSRAPS
PRRSAGDGRFILPPRIHRASDPGLPPGFKRSTIQPQKALAEEEVSLRAPYDAELAPPVDA
YAHPPPLARILSPQAGQQQILPHPQTSPLLHPLVGQHILSVRQFSKEQMSHLFNVAHTLR
LMVQKERPLDILKGKVMASMFYEVSTRTSSSFAAAMHRLGGSVVHFSESTSSTQKGESLA
DSVHTMSCYSDVIVLRHPVPGAVESAARHCRRPVINAGDGVGEHPTQALLDIFTIREELG
TVNGMTITMVGDLKHGRTVHSLARLLTQYRITLRYVAPKNLSMPAEIIDFVASKGIKQEE
FNSIEEALPDTDVLYMTRIQKERFASEEEYKACFGQFILTPHIMTGAKRKMVVMHPLPRV
NEISAEVDTDPRAAYFRQAENGMYIRMALLATVLGR
NT seq
6771 nt
NT seq
+upstream
nt +downstream
nt
atgctgctgaaaatggcatctttagtactggaggacgggacaacattcaaaggccgcctg
ttcggtgcggtatcctcagtgtctggtgaagttgttttccagacaggaatggtgggttat
ccagaggctcttacagatccttcttacaagtctcaaatactaacactcacatacccgctg
attggcaattatggtattcctgaagatgaagatggagagtttggactcagcaagtggttt
gaatcttccaaaatccatgcttcagctctcattgttggggagctctctgagaatcccagt
cactggagctccgccaagtctctggatcagtggctccgagagcaaggcatccctggactt
gaaggggttgacactcgaagcttgacccaaaagatcagagaaaagggaaccatgttgggg
aaactggtggtggaaggaacttcagccaatgacattccgtttgacaatccagacaaccgg
aatctcattaaagaagtttccatgaaagaaccaaaagtttttaatccagagggcacagtc
agaatcactgccgtagactgtggcatcaagtacaaccagatccgttgcctgtgccagaga
ggtgcccgggtaacagttgtcccctgggatcatcctctagacagtaacgactttgatggg
ttgttcatcagcaatggtcctggcaatcctgagtactgtaaggagactgtagagaatata
cggaaggtggcatgtgtggagaatcctaaacctgtctttgggatttgtctgggccatcag
ctgctgtctttggtcattggcgcaaagacatacaaaatgaaatatggtaatcgtggccat
aaccaaccctgcatccataaaggaacaaatcgctgtttcatcacctctcagaatcatggg
ttcgctgtggatcccaaaacactcccagaagactgggatgtgctcttcaccaacgccaat
gaccaaaccagtgaaggcatcgttcacaaccacaaaccactcttcagtgtccagtttcat
cctgaacacatggctggtccaacagaccttgttggtctctttgatgtgtttctggaaacc
gtcaaagatgctaaagagggcaaagctggaaaatcagttaagcaaagattaacagagcac
ctcacttaccctggatctcctgacccggaagcatttgttcgacctcgtaaagttctggtt
ttaggttcaggagggctttccattggacaggctggagagtttgactattctggatctcag
gctataaaagctctgaaagaagagaacatccaaacagtcctcatcaaccccaacattgcc
acagtacagacctcaaagggcctggcagataaagtctacttcctcccaatcacaccagag
tatgtcacacaggtgataaagaatgagcgtccagacggggtgttgctcacatttggcggt
cagacggccctgaattgtggtgtggagctcactaaacaaggagtgctagaaaaatacaaa
gtacgtgtgcttggaaccccagtagcctctatagagatgactgaagacaggaagattttt
gtggagaagatggaggaaattaatgaacatgttgcccccagtgaagcagccatgtctgtt
gaacaggcagtagctgctgctgaaagacttggctatcccgtactggtccggtctgcgttt
gccctaggtggactgggttcaggctttgccaataatcgagaggagatgatcacattggtt
actcaggcctttgcccacacatcacaagtcctggttgacaaatctctcaaaggctggaag
gaaatagagtatgaagtggtgcgggacgcctatgataattgcattacggtttgtaacatg
gagaacgttgatcctctaggaatccacactggggagtccatagtggtggctcctagtcag
acgctgaatgactatgaatacaatatgctgagaaacacggccatcaaagttattcgccac
ttgggcattgtgggagagtgcaacattcagtatgccctaaatcctgaatctgagcagtac
tacatcattgaagtaaacgctcgtctctcacgaagctctgcgttggccagtaaggccaca
ggttacccgctggcttacgtggcagccaagcttggcttgggaatccctctgcccaagctc
aagaactcagtgactaattccacaacagccaactttgagccaagtctggattactgtgtg
gtgaaggttcctcgttgggatttgagcaagttcctcagagtcagcactaaaattggcagt
tccatgaagagcgttggagaagtgatggccattggccgcagctttgaagaggccttccag
aaagctttgagaatggtggatgagaactgcgttggttttgaccacaccatcaaaccagtg
tctgaagaggagctgcagacacccacagacaagcgcatctttgttctggcgggtgccctg
cgtgcaggctacaccgttgagcggctctatgagctgaccaaaatagaccactggtttctg
cacaagatgaagaacatcgcagaccatgagaaacttctagaggcatataataaggatgag
agtgccatgccacctgaggtcatgaggaaagccaagcagctgggtttctccgacaaacag
atcgctcaagctgtgcagagcactgagctggctgtgaggaagatgagacgtgactggaag
atccttccagtggtcaaacagattgacacagtggccgccgagtggcccgcccacaccaac
tatctgtatctgacctatcacggctcagaaagcgatgtgattttcaagcaaccccatgtc
atggtgatcggctctggggtttaccgaattggaagcagcgtggagttcgattggtgcgct
gttgggtgtattatggagctgaggaagatgggatacaaaacaattatggtgaactacaac
ccagaaacagttagcacagattatgatatgtgcgacagactgtattttgatgagatttca
tttgaggtagtgatggacatatatgagatggagaacccagagggaattattctgtccatg
ggtggacagctgcccaacaacattgccatgtccttgcatagacagcagtgcaggatcctg
ggcacctcacctgagttcattgactctgcggagaaccgcttcaaattctccaggatgctg
gacaccataggaatcagccagccccgatggaaagagctgtctgatactgagtctgctgtg
ggtttctgtgagacggtgggttatccctgcttagtgaggccgtcgtatgttctcagcggg
gctgctatgaatgttgccttctcagacactgacctggaaaggttcctaagcagtgcagtt
gctctgtcaaaggaacaccctgttgttatctccaaattcattcaggaggccaaggaaata
gatgtggacgctgtggcctgtgacggagaggtcattgccatagcggtgtctgagcatgtg
gagaacgcaggggtgcattctggagatgccacgctggtgaccccacctcaggatatcaac
cagaaaaccatggagcgcattaagataatcgttcacgcaattggccaggagcttcaggtc
accggccccttcaacctgcagctcattgccaaggatgatcaactgaaggtgatagaatgc
aatgtgcgagtctcacgctccttcccttttgtgtccaaaacacttggtgtcgatcttgtt
gccctagcaacaagagtcattatgggagaggaagtcgaggatgtcgggctgatgaaaggg
aatggcattgtgggagttaaggttcctcagttctccttctcacgccttgctggagcagat
gtggttttaggtgtggagatgaccagcactggagaagtggcctgcttcggggagaaccga
tacgaggcctaccttaaagccatgctcagcactggctttaaaatccctaaaaagaatatt
ctcctctctattggtagttacaagaataagagcgagctcctgcagacagtccagactttg
gaggttttaggttataacttgtatgccagtctaggcaccgctgacttctacactgaacat
ggagtcaaggtgatggcagtggactggccttttgaagaggagagtgactgcccaaataag
gacaaacaaaggaacatcatggactatctggcagagaaccattttgacttggtcatcaat
ctgtccatgagaaactctggtggaagacgcttgtcctcctttgtgaccaaaggttatcgc
actcgtcgaatggccattgattactccgtaccgctcatcactgacatcaagtgcaccaag
ttgtttgttcaggcactgaggcaaattggccaggctcctcatgtaaagactcatgtcgac
agcatgacctcacagaagctcatccgtttacctggtttgattgatgtccatgtgcatctg
cgggagcctggtgccacccataaagaagatttttcctcgggcacagctgctgccctggct
ggaggaatcactatggtgtgttccatgcccaataccaaccctgccatcattgaccccagc
accttcgctatggcacagaagcttgccaaggccggatgccgctgtgattatgctcttttt
gtgggggcgtcatcagacaacgctacactacttccgtccattgcaagctctgcagctggt
ctgaagatgtacttgaatgacacatactccactttgaaaatggacaatgtttctctgtgg
atggagcactttgaaaagtggccaaagcacttgcccattgtggcacatgcagagaagcag
acagtggctgcaatcttgatggtagcgcagctatatcagcgacccgttcatatttgccat
gttgccaagaaagaagagattctgataattcgagcagctaaacaaaagggcatccaggtg
acatgtgaagttgcacctcaccatctcttcctgtgtgacgataacgtgtctgcaattggg
aacggcagggcacaagtgcggcccatgcttggtactcgtgaggacatggaggcgttgtgg
gaaaatttagacatcattgactgtttcgcaacagaccacgcccctcattcggtcgaggag
aaaaactctgagaaaccacctccaggttacccgggtttggagactatgctgcctctgctg
ctcacggccgtcagcgatggtcgtcttaccgttgatgacatcatcaagaggctctatgaa
aaccccagtaaaatattctctcttcctgttcaagaggacacttatgtagaggtggacttg
gagcaagagtggactattccaaagcacatgcaattcaccaagtcaaagtggacaccattc
gggggcatgaaagtaaaggggaaagtcatgagggtggtgctcagaggagaggtggcctat
attgatggacaggtattggtacctccaggatatggtcaggatgtgaggtcatggtcacca
cccccggcagtaacaacagaggtgataaaggatgctcctaagcgtctaagtgagacaata
actcctgagcgcccccgccagacggcacctgctgatgtggtccgtagccgtgccccaagc
ccacgccgttcagctggagacggtcgcttcattcttccacctcgtatccaccgtgcatcc
gatcccggtctgcctccaggtttcaaaagatctaccatacaaccccaaaaggcattggct
gaagaggaggtgtcattaagagcaccgtatgatgcagaattggctcccccagtggatgca
tatgcacaccctcctcccctggccaggatcctgtcacctcaagctgggcagcagcagatc
ctgccccacccccagacctcccctttgctgcacccactggtgggccagcacatcttgtcc
gtgcgccagttcagcaaggaacagatgtcacacttgttcaatgtggcacatactcttcgt
ctgatggtgcagaaggaaagacccttggatattttgaagggtaaagtcatggcctccatg
ttctacgaggtgagcactcgcaccagcagttcattcgcagctgccatgcaccgtctagga
gggtcggtggtgcatttcagtgagtccacgtcctccacgcagaagggcgagtctctggct
gattctgttcacaccatgagctgctactctgatgtcattgttctgcgccaccccgtacct
ggagctgtagaaagtgcagcaaggcattgtcggcggccggtgatcaacgctggtgatggt
gttggagaacatcccactcaggcccttctggatatctttacgatcagagaggagctggga
acagtcaatggcatgactattaccatggtaggtgatctgaaacatggccgtactgtgcat
tctctggctagacttctcactcaatacaggatcaccttgcgctatgtggcccccaagaac
ctcagcatgcctgctgaaatcatcgatttcgtagcctccaaaggcattaaacaggaggag
tttaacagcattgaagaggcccttccagacactgacgtcctatacatgaccagaatacaa
aaggagcgattcgcctctgaagaagagtacaaagcgtgtttcggccagtttatcctaacc
ccacatatcatgacgggagccaaaagaaagatggtggtcatgcatcctcttcccagagtc
aatgagatcagtgcggaagtggacacggatcctcgggctgcttacttccgccaggcggag
aacgggatgtatattcggatggcgctgctggctactgtgctgggtcggtga
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integrated database retrieval system