KEGG   Garra rufa (doctor fish): 141348592
Entry
141348592         CDS       T11039                                 
Symbol
cad
Name
(RefSeq) multifunctional protein CAD isoform X1
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
grf  Garra rufa (doctor fish)
Pathway
grf00220  Arginine biosynthesis
grf00240  Pyrimidine metabolism
grf00250  Alanine, aspartate and glutamate metabolism
grf01100  Metabolic pathways
grf01240  Biosynthesis of cofactors
Module
grf_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:grf00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    141348592 (cad)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    141348592 (cad)
   00220 Arginine biosynthesis
    141348592 (cad)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:grf01002]
    141348592 (cad)
Enzymes [BR:grf01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     141348592 (cad)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     141348592 (cad)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     141348592 (cad)
Peptidases and inhibitors [BR:grf01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   141348592 (cad)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   141348592 (cad)
SSDB
Motif
Pfam: CPSase_L_D2 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 MGS ATP-grasp Dala_Dala_lig_C ATPgrasp_Ter Amidohydro_1 ATP-grasp_3 Peptidase_C26 RimK DJ-1_PfpI GSH-S_ATP
Other DBs
NCBI-GeneID: 141348592
NCBI-ProteinID: XP_073708967
LinkDB
Position
13:complement(34230933..34262558)
AA seq 2256 aa
MLLKMASLVLEDGTTFKGRLFGAVSSVSGEVVFQTGMVGYPEALTDPSYKSQILTLTYPL
IGNYGIPEDEDGEFGLSKWFESSKIHASALIVGELSENPSHWSSAKSLDQWLREQGIPGL
EGVDTRSLTQKIREKGTMLGKLVVEGTSANDIPFDNPDNRNLIKEVSMKEPKVFNPEGTV
RITAVDCGIKYNQIRCLCQRGARVTVVPWDHPLDSNDFDGLFISNGPGNPEYCKETVENI
RKVACVENPKPVFGICLGHQLLSLVIGAKTYKMKYGNRGHNQPCIHKGTNRCFITSQNHG
FAVDPKTLPEDWDVLFTNANDQTSEGIVHNHKPLFSVQFHPEHMAGPTDLVGLFDVFLET
VKDAKEGKAGKSVKQRLTEHLTYPGSPDPEAFVRPRKVLVLGSGGLSIGQAGEFDYSGSQ
AIKALKEENIQTVLINPNIATVQTSKGLADKVYFLPITPEYVTQVIKNERPDGVLLTFGG
QTALNCGVELTKQGVLEKYKVRVLGTPVASIEMTEDRKIFVEKMEEINEHVAPSEAAMSV
EQAVAAAERLGYPVLVRSAFALGGLGSGFANNREEMITLVTQAFAHTSQVLVDKSLKGWK
EIEYEVVRDAYDNCITVCNMENVDPLGIHTGESIVVAPSQTLNDYEYNMLRNTAIKVIRH
LGIVGECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLGLGIPLPKL
KNSVTNSTTANFEPSLDYCVVKVPRWDLSKFLRVSTKIGSSMKSVGEVMAIGRSFEEAFQ
KALRMVDENCVGFDHTIKPVSEEELQTPTDKRIFVLAGALRAGYTVERLYELTKIDHWFL
HKMKNIADHEKLLEAYNKDESAMPPEVMRKAKQLGFSDKQIAQAVQSTELAVRKMRRDWK
ILPVVKQIDTVAAEWPAHTNYLYLTYHGSESDVIFKQPHVMVIGSGVYRIGSSVEFDWCA
VGCIMELRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYEMENPEGIILSM
GGQLPNNIAMSLHRQQCRILGTSPEFIDSAENRFKFSRMLDTIGISQPRWKELSDTESAV
GFCETVGYPCLVRPSYVLSGAAMNVAFSDTDLERFLSSAVALSKEHPVVISKFIQEAKEI
DVDAVACDGEVIAIAVSEHVENAGVHSGDATLVTPPQDINQKTMERIKIIVHAIGQELQV
TGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEDVGLMKG
NGIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPKKNI
LLSIGSYKNKSELLQTVQTLEVLGYNLYASLGTADFYTEHGVKVMAVDWPFEEESDCPNK
DKQRNIMDYLAENHFDLVINLSMRNSGGRRLSSFVTKGYRTRRMAIDYSVPLITDIKCTK
LFVQALRQIGQAPHVKTHVDSMTSQKLIRLPGLIDVHVHLREPGATHKEDFSSGTAAALA
GGITMVCSMPNTNPAIIDPSTFAMAQKLAKAGCRCDYALFVGASSDNATLLPSIASSAAG
LKMYLNDTYSTLKMDNVSLWMEHFEKWPKHLPIVAHAEKQTVAAILMVAQLYQRPVHICH
VAKKEEILIIRAAKQKGIQVTCEVAPHHLFLCDDNVSAIGNGRAQVRPMLGTREDMEALW
ENLDIIDCFATDHAPHSVEEKNSEKPPPGYPGLETMLPLLLTAVSDGRLTVDDIIKRLYE
NPSKIFSLPVQEDTYVEVDLEQEWTIPKHMQFTKSKWTPFGGMKVKGKVMRVVLRGEVAY
IDGQVLVPPGYGQDVRSWSPPPAVTTEVIKDAPKRLSETITPERPRQTAPADVVRSRAPS
PRRSAGDGRFILPPRIHRASDPGLPPGFKRSTIQPQKALAEEEVSLRAPYDAELAPPVDA
YAHPPPLARILSPQAGQQQILPHPQTSPLLHPLVGQHILSVRQFSKEQMSHLFNVAHTLR
LMVQKERPLDILKGKVMASMFYEVSTRTSSSFAAAMHRLGGSVVHFSESTSSTQKGESLA
DSVHTMSCYSDVIVLRHPVPGAVESAARHCRRPVINAGDGVGEHPTQALLDIFTIREELG
TVNGMTITMVGDLKHGRTVHSLARLLTQYRITLRYVAPKNLSMPAEIIDFVASKGIKQEE
FNSIEEALPDTDVLYMTRIQKERFASEEEYKACFGQFILTPHIMTGAKRKMVVMHPLPRV
NEISAEVDTDPRAAYFRQAENGMYIRMALLATVLGR
NT seq 6771 nt   +upstreamnt  +downstreamnt
atgctgctgaaaatggcatctttagtactggaggacgggacaacattcaaaggccgcctg
ttcggtgcggtatcctcagtgtctggtgaagttgttttccagacaggaatggtgggttat
ccagaggctcttacagatccttcttacaagtctcaaatactaacactcacatacccgctg
attggcaattatggtattcctgaagatgaagatggagagtttggactcagcaagtggttt
gaatcttccaaaatccatgcttcagctctcattgttggggagctctctgagaatcccagt
cactggagctccgccaagtctctggatcagtggctccgagagcaaggcatccctggactt
gaaggggttgacactcgaagcttgacccaaaagatcagagaaaagggaaccatgttgggg
aaactggtggtggaaggaacttcagccaatgacattccgtttgacaatccagacaaccgg
aatctcattaaagaagtttccatgaaagaaccaaaagtttttaatccagagggcacagtc
agaatcactgccgtagactgtggcatcaagtacaaccagatccgttgcctgtgccagaga
ggtgcccgggtaacagttgtcccctgggatcatcctctagacagtaacgactttgatggg
ttgttcatcagcaatggtcctggcaatcctgagtactgtaaggagactgtagagaatata
cggaaggtggcatgtgtggagaatcctaaacctgtctttgggatttgtctgggccatcag
ctgctgtctttggtcattggcgcaaagacatacaaaatgaaatatggtaatcgtggccat
aaccaaccctgcatccataaaggaacaaatcgctgtttcatcacctctcagaatcatggg
ttcgctgtggatcccaaaacactcccagaagactgggatgtgctcttcaccaacgccaat
gaccaaaccagtgaaggcatcgttcacaaccacaaaccactcttcagtgtccagtttcat
cctgaacacatggctggtccaacagaccttgttggtctctttgatgtgtttctggaaacc
gtcaaagatgctaaagagggcaaagctggaaaatcagttaagcaaagattaacagagcac
ctcacttaccctggatctcctgacccggaagcatttgttcgacctcgtaaagttctggtt
ttaggttcaggagggctttccattggacaggctggagagtttgactattctggatctcag
gctataaaagctctgaaagaagagaacatccaaacagtcctcatcaaccccaacattgcc
acagtacagacctcaaagggcctggcagataaagtctacttcctcccaatcacaccagag
tatgtcacacaggtgataaagaatgagcgtccagacggggtgttgctcacatttggcggt
cagacggccctgaattgtggtgtggagctcactaaacaaggagtgctagaaaaatacaaa
gtacgtgtgcttggaaccccagtagcctctatagagatgactgaagacaggaagattttt
gtggagaagatggaggaaattaatgaacatgttgcccccagtgaagcagccatgtctgtt
gaacaggcagtagctgctgctgaaagacttggctatcccgtactggtccggtctgcgttt
gccctaggtggactgggttcaggctttgccaataatcgagaggagatgatcacattggtt
actcaggcctttgcccacacatcacaagtcctggttgacaaatctctcaaaggctggaag
gaaatagagtatgaagtggtgcgggacgcctatgataattgcattacggtttgtaacatg
gagaacgttgatcctctaggaatccacactggggagtccatagtggtggctcctagtcag
acgctgaatgactatgaatacaatatgctgagaaacacggccatcaaagttattcgccac
ttgggcattgtgggagagtgcaacattcagtatgccctaaatcctgaatctgagcagtac
tacatcattgaagtaaacgctcgtctctcacgaagctctgcgttggccagtaaggccaca
ggttacccgctggcttacgtggcagccaagcttggcttgggaatccctctgcccaagctc
aagaactcagtgactaattccacaacagccaactttgagccaagtctggattactgtgtg
gtgaaggttcctcgttgggatttgagcaagttcctcagagtcagcactaaaattggcagt
tccatgaagagcgttggagaagtgatggccattggccgcagctttgaagaggccttccag
aaagctttgagaatggtggatgagaactgcgttggttttgaccacaccatcaaaccagtg
tctgaagaggagctgcagacacccacagacaagcgcatctttgttctggcgggtgccctg
cgtgcaggctacaccgttgagcggctctatgagctgaccaaaatagaccactggtttctg
cacaagatgaagaacatcgcagaccatgagaaacttctagaggcatataataaggatgag
agtgccatgccacctgaggtcatgaggaaagccaagcagctgggtttctccgacaaacag
atcgctcaagctgtgcagagcactgagctggctgtgaggaagatgagacgtgactggaag
atccttccagtggtcaaacagattgacacagtggccgccgagtggcccgcccacaccaac
tatctgtatctgacctatcacggctcagaaagcgatgtgattttcaagcaaccccatgtc
atggtgatcggctctggggtttaccgaattggaagcagcgtggagttcgattggtgcgct
gttgggtgtattatggagctgaggaagatgggatacaaaacaattatggtgaactacaac
ccagaaacagttagcacagattatgatatgtgcgacagactgtattttgatgagatttca
tttgaggtagtgatggacatatatgagatggagaacccagagggaattattctgtccatg
ggtggacagctgcccaacaacattgccatgtccttgcatagacagcagtgcaggatcctg
ggcacctcacctgagttcattgactctgcggagaaccgcttcaaattctccaggatgctg
gacaccataggaatcagccagccccgatggaaagagctgtctgatactgagtctgctgtg
ggtttctgtgagacggtgggttatccctgcttagtgaggccgtcgtatgttctcagcggg
gctgctatgaatgttgccttctcagacactgacctggaaaggttcctaagcagtgcagtt
gctctgtcaaaggaacaccctgttgttatctccaaattcattcaggaggccaaggaaata
gatgtggacgctgtggcctgtgacggagaggtcattgccatagcggtgtctgagcatgtg
gagaacgcaggggtgcattctggagatgccacgctggtgaccccacctcaggatatcaac
cagaaaaccatggagcgcattaagataatcgttcacgcaattggccaggagcttcaggtc
accggccccttcaacctgcagctcattgccaaggatgatcaactgaaggtgatagaatgc
aatgtgcgagtctcacgctccttcccttttgtgtccaaaacacttggtgtcgatcttgtt
gccctagcaacaagagtcattatgggagaggaagtcgaggatgtcgggctgatgaaaggg
aatggcattgtgggagttaaggttcctcagttctccttctcacgccttgctggagcagat
gtggttttaggtgtggagatgaccagcactggagaagtggcctgcttcggggagaaccga
tacgaggcctaccttaaagccatgctcagcactggctttaaaatccctaaaaagaatatt
ctcctctctattggtagttacaagaataagagcgagctcctgcagacagtccagactttg
gaggttttaggttataacttgtatgccagtctaggcaccgctgacttctacactgaacat
ggagtcaaggtgatggcagtggactggccttttgaagaggagagtgactgcccaaataag
gacaaacaaaggaacatcatggactatctggcagagaaccattttgacttggtcatcaat
ctgtccatgagaaactctggtggaagacgcttgtcctcctttgtgaccaaaggttatcgc
actcgtcgaatggccattgattactccgtaccgctcatcactgacatcaagtgcaccaag
ttgtttgttcaggcactgaggcaaattggccaggctcctcatgtaaagactcatgtcgac
agcatgacctcacagaagctcatccgtttacctggtttgattgatgtccatgtgcatctg
cgggagcctggtgccacccataaagaagatttttcctcgggcacagctgctgccctggct
ggaggaatcactatggtgtgttccatgcccaataccaaccctgccatcattgaccccagc
accttcgctatggcacagaagcttgccaaggccggatgccgctgtgattatgctcttttt
gtgggggcgtcatcagacaacgctacactacttccgtccattgcaagctctgcagctggt
ctgaagatgtacttgaatgacacatactccactttgaaaatggacaatgtttctctgtgg
atggagcactttgaaaagtggccaaagcacttgcccattgtggcacatgcagagaagcag
acagtggctgcaatcttgatggtagcgcagctatatcagcgacccgttcatatttgccat
gttgccaagaaagaagagattctgataattcgagcagctaaacaaaagggcatccaggtg
acatgtgaagttgcacctcaccatctcttcctgtgtgacgataacgtgtctgcaattggg
aacggcagggcacaagtgcggcccatgcttggtactcgtgaggacatggaggcgttgtgg
gaaaatttagacatcattgactgtttcgcaacagaccacgcccctcattcggtcgaggag
aaaaactctgagaaaccacctccaggttacccgggtttggagactatgctgcctctgctg
ctcacggccgtcagcgatggtcgtcttaccgttgatgacatcatcaagaggctctatgaa
aaccccagtaaaatattctctcttcctgttcaagaggacacttatgtagaggtggacttg
gagcaagagtggactattccaaagcacatgcaattcaccaagtcaaagtggacaccattc
gggggcatgaaagtaaaggggaaagtcatgagggtggtgctcagaggagaggtggcctat
attgatggacaggtattggtacctccaggatatggtcaggatgtgaggtcatggtcacca
cccccggcagtaacaacagaggtgataaaggatgctcctaagcgtctaagtgagacaata
actcctgagcgcccccgccagacggcacctgctgatgtggtccgtagccgtgccccaagc
ccacgccgttcagctggagacggtcgcttcattcttccacctcgtatccaccgtgcatcc
gatcccggtctgcctccaggtttcaaaagatctaccatacaaccccaaaaggcattggct
gaagaggaggtgtcattaagagcaccgtatgatgcagaattggctcccccagtggatgca
tatgcacaccctcctcccctggccaggatcctgtcacctcaagctgggcagcagcagatc
ctgccccacccccagacctcccctttgctgcacccactggtgggccagcacatcttgtcc
gtgcgccagttcagcaaggaacagatgtcacacttgttcaatgtggcacatactcttcgt
ctgatggtgcagaaggaaagacccttggatattttgaagggtaaagtcatggcctccatg
ttctacgaggtgagcactcgcaccagcagttcattcgcagctgccatgcaccgtctagga
gggtcggtggtgcatttcagtgagtccacgtcctccacgcagaagggcgagtctctggct
gattctgttcacaccatgagctgctactctgatgtcattgttctgcgccaccccgtacct
ggagctgtagaaagtgcagcaaggcattgtcggcggccggtgatcaacgctggtgatggt
gttggagaacatcccactcaggcccttctggatatctttacgatcagagaggagctggga
acagtcaatggcatgactattaccatggtaggtgatctgaaacatggccgtactgtgcat
tctctggctagacttctcactcaatacaggatcaccttgcgctatgtggcccccaagaac
ctcagcatgcctgctgaaatcatcgatttcgtagcctccaaaggcattaaacaggaggag
tttaacagcattgaagaggcccttccagacactgacgtcctatacatgaccagaatacaa
aaggagcgattcgcctctgaagaagagtacaaagcgtgtttcggccagtttatcctaacc
ccacatatcatgacgggagccaaaagaaagatggtggtcatgcatcctcttcccagagtc
aatgagatcagtgcggaagtggacacggatcctcgggctgcttacttccgccaggcggag
aacgggatgtatattcggatggcgctgctggctactgtgctgggtcggtga

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